Protein: MED29
Mediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29)

Gene: MED29
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q9NX70

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1431401

MED28
Mediator of RNA polymerase II transcription subunit 28

6

1

Small-scale

0.949

High

1393384

MED30
Mediator of RNA polymerase II transcription subunit 30

5

1

Small-scale

0.927

High

1401572

MED15
Mediator of RNA polymerase II transcription subunit 15

4

2

High-throughput

0.903

High

1451899

MED16
Mediator of RNA polymerase II transcription subunit 16

4

1

High-throughput

0.903

High

1451886

MED29
Mediator of RNA polymerase II transcription subunit 29

4

0

Small-scale

0.862

High

881616

CDK8
Cyclin-dependent kinase 8

11

3

High-throughput

0.759

High

1414148

MED18
Mediator of RNA polymerase II transcription subunit 18

9

1

Small-scale

0.756

High

1436782

MED20
Mediator of RNA polymerase II transcription subunit 20

8

1

Small-scale

0.754

High

1450381

MED17
Mediator of RNA polymerase II transcription subunit 17

8

1

Small-scale

0.752

High

1391342

MED8
Mediator of RNA polymerase II transcription subunit 8

7

1

Small-scale

0.750

High

1451888

MED11
Mediator of RNA polymerase II transcription subunit 11

7

1

Small-scale

0.750

High

1446526

MED4
Mediator of RNA polymerase II transcription subunit 4

7

1

Small-scale

0.749

High

1372206

MED12
Mediator of RNA polymerase II transcription subunit 12

7

2

Small-scale

0.749

High

1416407

CDK19
Cyclin-dependent kinase 19

7

3

High-throughput

0.748

High

666920

CCNC
Cyclin-C

7

2

High-throughput

0.745

High

219523

MED7
Mediator of RNA polymerase II transcription subunit 7

6

1

High-throughput

0.738

High

1413636

MED10
Mediator of RNA polymerase II transcription subunit 10

6

1

Small-scale

0.738

High

1451891

MED13
Mediator of RNA polymerase II transcription subunit 13

6

2

Small-scale

0.736

High

287825

MED6
Mediator of RNA polymerase II transcription subunit 6

6

2

Small-scale

0.736

High

49026

MED19
Mediator of RNA polymerase II transcription subunit 19

10

0

Small-scale

0.726

High

1451901

MED31
Mediator of RNA polymerase II transcription subunit 31

5

1

Small-scale

0.722

High

1151300

MED1
Mediator of RNA polymerase II transcription subunit 1

8

0

Small-scale

0.721

High

1108409

MED21
Mediator of RNA polymerase II transcription subunit 21

7

0

Small-scale

0.718

High

1149716

MED22
Mediator of RNA polymerase II transcription subunit 22

6

0

Small-scale

0.702

High

239624

MED14
Mediator of RNA polymerase II transcription subunit 14

4

2

High-throughput

0.699

High

282425

MED24
Mediator of RNA polymerase II transcription subunit 24

4

1

High-throughput

0.699

High

1241419

MED27
Mediator of RNA polymerase II transcription subunit 27

4

1

High-throughput

0.699

High

1259074

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

4

2

High-throughput

0.699

High

1451893

MED23
Mediator of RNA polymerase II transcription subunit 23

4

1

High-throughput

0.699

High

336035

MED26
Mediator of RNA polymerase II transcription subunit 26

5

0

High-throughput

0.691

High

1451133

MED9
Mediator of RNA polymerase II transcription subunit 9

5

0

Small-scale

0.691

High

1259287

MED25
Mediator of RNA polymerase II transcription subunit 25

3

1

High-throughput

0.675

High

1295680

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

3

2

High-throughput

0.667

High

912251

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

4

0

High-throughput

0.661

High

217212

MS18B
Protein Mis18-beta

3

0

High-throughput

0.638

High

1451887

ABI2
Abl interactor 2

2

1

High-throughput

0.606

High

188723

BIRC5
Baculoviral IAP repeat-containing protein 5

2

0

High-throughput

0.602

High

192874

RPB4
DNA-directed RNA polymerase II subunit RPB4

2

0

High-throughput

0.602

High

621773

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

High-throughput

0.602

High

621995

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

2

0

High-throughput

0.602

High

667484

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

0

High-throughput

0.602

High

723122

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

0

High-throughput

0.602

High

976166

RPB7
DNA-directed RNA polymerase II subunit RPB7

2

0

High-throughput

0.602

High

1243782

FXL19
F-box/LRR-repeat protein 19

2

0

High-throughput

0.602

High

260535

BRD4
Bromodomain-containing protein 4

2

1

High-throughput

0.584

High

298103

SPF27
Pre-mRNA-splicing factor SPF27

2

0

High-throughput

0.580

High

1435946

NRDE2
Nuclear exosome regulator NRDE2

2

0

High-throughput

0.580

High

1385308

ZBTB9
Zinc finger and BTB domain-containing protein 9

2

0

High-throughput

0.576

High

1451889

ABI3
ABI gene family member 3

2

1

High-throughput

0.553

High

1287329

TAD2B
Transcriptional adapter 2-beta

1

2

High-throughput

0.536

High

225173

TRIA1
TP53-regulated inhibitor of apoptosis 1

1

0

High-throughput

0.513

High

228048

SSNA1
Microtubule nucleation factor SSNA1

1

0

High-throughput

0.513

High

317424

KPCD3
Serine/threonine-protein kinase D3

1

0

High-throughput

0.513

High

659614

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.513

High

787803

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.513

High

912143

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.513

High

923558

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

959077

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

983723

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.513

High

1211478

BEND6
BEN domain-containing protein 6

1

0

High-throughput

0.513

High

1361171

PIBF1
Progesterone-induced-blocking factor 1

1

0

High-throughput

0.513

High

1390135

ADAT3
Probable inactive tRNA-specific adenosine deaminase-like protein 3

1

0

High-throughput

0.513

High

1451897

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.513

High

578557

BRAF
Serine/threonine-protein kinase B-raf

1

0

High-throughput

0.484

High

181949

SMAD9
Mothers against decapentaplegic homolog 9

1

1

Small-scale

0.479

High

283560

TAD2A
Transcriptional adapter 2-alpha

1

2

High-throughput

0.479

High

674353

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.479

High

1406698

SMAD5
Mothers against decapentaplegic homolog 5

1

1

Small-scale

0.479

High

278985

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

569142

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.458

High

980440

H4
Histone H4

1

0

High-throughput

0.458

High

1143560

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.458

High

1212049

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

0

High-throughput

0.458

High

1257831

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

1380204

FBXW7
F-box/WD repeat-containing protein 7

1

0

Small-scale

0.458

High

1400084

QKI
KH domain-containing RNA-binding protein QKI

1

0

High-throughput

0.458

High

1407426

EPAS1
Endothelial PAS domain-containing protein 1

1

0

Small-scale

0.458

High

1434836

STN1
CST complex subunit STN1

1

0

High-throughput

0.458

High

95762

E5RFK5
Cyclin-C

1

2

High-throughput

0.445

High

533308

THA
Thyroid hormone receptor alpha

1

1

Small-scale

0.445

High

1436292

DDX31
ATP-dependent DNA helicase DDX31

1

1

High-throughput

0.445

High

1451890

DDX20
Probable ATP-dependent RNA helicase DDX20

1

1

High-throughput

0.445

High

1451894

PRP19
Pre-mRNA-processing factor 19

1

2

High-throughput

0.445

High

1451898

DDX52
Probable ATP-dependent RNA helicase DDX52

1

1

High-throughput

0.445

High

1227570

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.437

High

141680

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

High-throughput

0.426

High

160017

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.426

High

175793

SR140
U2 snRNP-associated SURP motif-containing protein

1

0

High-throughput

0.426

High

330519

LC7L3
Luc7-like protein 3

1

0

High-throughput

0.426

High

348772

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.426

High

447509

NPM
Nucleophosmin

1

0

High-throughput

0.426

High

507392

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

0

High-throughput

0.426

High

687527

PTBP1
Polypyrimidine tract-binding protein 1

1

0

High-throughput

0.426

High

727994

DNJA1
DnaJ homolog subfamily A member 1

1

0

High-throughput

0.426

High

761525

HS71L
Heat shock 70 kDa protein 1-like

1

0

High-throughput

0.426

High

837421

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

0

High-throughput

0.426

High

910709

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.426

High

974485

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.426

High

996367

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.426

High

1016647

SRSF3
Serine/arginine-rich splicing factor 3

1

0

High-throughput

0.426

High

1096246

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.426

High

1127197

RBM39
RNA-binding protein 39

1

0

High-throughput

0.426

High

1144489

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.426

High

1410755

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.426

High

1451892

TR112
Multifunctional methyltransferase subunit TRM112-like protein

1

0

High-throughput

0.426

High

1451895

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.426

High

1451896

DICER
Endoribonuclease Dicer

1

0

High-throughput

0.426

High

1451900

NOP58
Nucleolar protein 58

1

0

High-throughput

0.426

High

76443

B4DUB1
cyclin-dependent kinase

1

3

High-throughput

0.407

High

887267

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

352647

TCL1B
T-cell leukemia/lymphoma protein 1B

3

0

High-throughput

0.347

High

1326749

MIA40
Mitochondrial intermembrane space import and assembly protein 40

3

0

Small-scale

0.335

High

51372

SRCRL
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

2

0

High-throughput

0.316

High

1124237

EI2BA
Translation initiation factor eIF2B subunit alpha

2

0

High-throughput

0.316

High

1208760

CL12A
C-type lectin domain family 12 member A

2

0

High-throughput

0.313

High

1239065

NIPA3
Magnesium transporter NIPA3

2

0

High-throughput

0.313

High

706334

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

984309

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.279

Low

1225922

STEA3
Metalloreductase STEAP3

1

0

High-throughput

0.279

Low

1313710

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.279

Low

1340039

O13G1
Olfactory receptor 13G1

1

0

High-throughput

0.279

Low

1348978

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

1395966

DNJC1
DnaJ homolog subfamily C member 1

1

0

High-throughput

0.279

Low

1397809

ODAD1
Outer dynein arm-docking complex subunit 1

1

0

High-throughput

0.279

Low

1110744

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.249

Low

347370

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.232

Low

882192

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low

896904

DYN2
Dynamin-2

1

0

High-throughput

0.232

Low

1361923

TITIN
Titin

1

0

High-throughput

0.232

Low

1365778

GCN1
Stalled ribosome sensor GCN1

1

0

High-throughput

0.232

Low

1382594

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.232

Low

1407822

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.232

Low

1410218

CMS1
Protein CMSS1

1

0

High-throughput

0.232

Low

1450537

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025