Protein: SPRNG
SREBP regulating gene protein (SREBF pathway regulator in Golgi 1)

Gene: SPRNG, SPRING1
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q9H741

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:2000640 - positive regulation of SREBP signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1131489

MBTP1
Membrane-bound transcription factor site-1 protease

2

0

Small-scale

0.748

High

1337957

ZNT7
Zinc transporter 7

3

0

High-throughput

0.634

High

699135

CALX
Calnexin

3

1

High-throughput

0.616

High

170967

CLGN
Calmegin

1

1

High-throughput

0.489

High

1105243

S39A6
Zinc transporter ZIP6

1

2

High-throughput

0.489

High

1105567

OS9
Protein OS-9

1

1

High-throughput

0.489

High

1363451

S39A7
Zinc transporter SLC39A7

1

2

High-throughput

0.489

High

1388099

ERLEC
Endoplasmic reticulum lectin 1

1

1

High-throughput

0.489

High

1435544

S39AA
Zinc transporter ZIP10

1

2

High-throughput

0.489

High

787895

SRBP1
Sterol regulatory element-binding protein 1

1

1

Small-scale

0.479

High

1085384

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

1

Small-scale

0.479

High

1085475

SRBP2
Sterol regulatory element-binding protein 2

1

1

Small-scale

0.479

High

178398

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.437

High

180593

PLS1
Phospholipid scramblase 1

2

0

High-throughput

0.328

High

828447

PEX19
Peroxisomal biogenesis factor 19

2

0

High-throughput

0.328

High

897606

KNTC1
Kinetochore-associated protein 1

2

0

High-throughput

0.328

High

1032660

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

0

High-throughput

0.328

High

1234003

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

2

0

High-throughput

0.328

High

1334324

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

2

0

High-throughput

0.328

High

1367860

HTRA1
Serine protease HTRA1

2

0

High-throughput

0.328

High

1430879

METL9
Protein-L-histidine N-pros-methyltransferase

2

0

High-throughput

0.328

High

1431685

ARV1
Protein ARV1

2

0

High-throughput

0.328

High

1203796

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.316

High

1146166

K1H1
Keratin, type I cuticular Ha1

1

0

High-throughput

0.299

High

1419223

TRI54
Tripartite motif-containing protein 54

1

0

High-throughput

0.299

High

215653

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.279

Low

231519

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.279

Low

536291

PPAL
Lysosomal acid phosphatase

1

0

High-throughput

0.279

Low

571252

PERF
Perforin-1

1

0

High-throughput

0.279

Low

922505

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.279

Low

992335

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.279

Low

1136367

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.279

Low

1238688

TM214
Transmembrane protein 214

1

0

High-throughput

0.279

Low

1287446

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

0

High-throughput

0.279

Low

1402118

LMF1
Lipase maturation factor 1

1

0

High-throughput

0.279

Low

1421134

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.279

Low

1435539

ZWILC
Protein zwilch homolog

1

0

High-throughput

0.279

Low

1435540

AT131
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.279

Low

1435541

FA8A1
Protein FAM8A1

1

0

High-throughput

0.279

Low

1435542

SE1L1
Protein sel-1 homolog 1

1

0

High-throughput

0.279

Low

1435543

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

1398264

TEAN2
Transcription elongation factor A N-terminal and central domain-containing protein 2

1

0

High-throughput

0.269

Low

1246112

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025