Protein: MBTP1
Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1)

Gene: MBTP1, MBTPS1
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q14703

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004252 - serine-type endopeptidase activity
GO:0005788 - endoplasmic reticulum lumen
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1131489

SPRNG
SREBP regulating gene protein

2

0

Small-scale

0.748

High

698661

CALX
Calnexin

4

2

High-throughput

0.691

High

168405

NCTR3
Natural cytotoxicity triggering receptor 3

1

3

High-throughput

0.618

High

731846

CEAM8
Cell adhesion molecule CEACAM8

1

1

High-throughput

0.618

High

1042619

UPAR
Urokinase plasminogen activator surface receptor

2

1

High-throughput

0.611

High

1131467

TAZ
Tafazzin

3

1

High-throughput

0.609

High

170765

CLGN
Calmegin

2

2

High-throughput

0.601

High

1131495

BTNL2
Butyrophilin-like protein 2

1

0

High-throughput

0.578

High

1131472

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

2

2

High-throughput

0.549

High

1131477

CA054
Uncharacterized protein C1orf54

2

2

High-throughput

0.549

High

1131498

CLC11
C-type lectin domain family 11 member A

2

3

High-throughput

0.549

High

593370

PGFRA
Platelet-derived growth factor receptor alpha

1

1

High-throughput

0.536

High

607372

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

3

High-throughput

0.536

High

1116201

PTC1
Protein patched homolog 1

1

2

High-throughput

0.536

High

1131491

SDF2L
Stromal cell-derived factor 2-like protein 1

1

3

High-throughput

0.536

High

1131494

DNJB9
DnaJ homolog subfamily B member 9

1

9

High-throughput

0.536

High

399443

TRGV3
T cell receptor gamma variable 3

1

2

High-throughput

0.514

High

341309

ECEL1
Endothelin-converting enzyme-like 1

1

0

High-throughput

0.513

High

519612

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.513

High

535062

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

548017

PSPC
Surfactant protein C

1

0

High-throughput

0.513

High

1131469

P3H1
Prolyl 3-hydroxylase 1

1

0

High-throughput

0.513

High

1131487

JMJD8
JmjC domain-containing protein 8

1

0

High-throughput

0.513

High

1106873

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

Small-scale

0.512

High

1109725

HDAC1
Histone deacetylase 1

1

3

Small-scale

0.512

High

154823

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

1

High-throughput

0.489

High

567864

PRG2
Bone marrow proteoglycan

1

6

High-throughput

0.489

High

935733

MFAP4
Microfibril-associated glycoprotein 4

1

3

High-throughput

0.489

High

1030164

IL5RA
Interleukin-5 receptor subunit alpha

1

5

High-throughput

0.489

High

1034730

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

1

High-throughput

0.489

High

1131468

CL12B
C-type lectin domain family 12 member B

1

2

High-throughput

0.489

High

1131481

GGH
Gamma-glutamyl hydrolase

1

2

High-throughput

0.489

High

1131482

TANK
TRAF family member-associated NF-kappa-B activator

1

1

High-throughput

0.489

High

1131484

T106A
Transmembrane protein 106A

1

1

High-throughput

0.489

High

1131466

CD226
CD226 antigen

1

0

High-throughput

0.481

High

218188

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

1131485

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1131492

SPHK1
Sphingosine kinase 1

1

1

Small-scale

0.457

High

142002

FCN1
Ficolin-1

1

3

Small-scale

0.457

High

1098397

DNJC3
DnaJ homolog subfamily C member 3

1

6

High-throughput

0.445

High

1131475

ZNT7
Zinc transporter 7

1

3

High-throughput

0.445

High

1131476

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

3

High-throughput

0.445

High

1131478

S39A7
Zinc transporter SLC39A7

1

4

High-throughput

0.445

High

1131479

SL9A6
Sodium/hydrogen exchanger 6

1

1

High-throughput

0.445

High

1131496

FBX2
F-box only protein 2

1

1

High-throughput

0.445

High

297607

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

High-throughput

0.437

High

714859

EF1D
Elongation factor 1-delta

1

1

High-throughput

0.437

High

1131480

HDAC2
Histone deacetylase 2

1

3

Small-scale

0.437

High

73806

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

3

High-throughput

0.407

High

1131470

SL9A4
Sodium/hydrogen exchanger 4

1

1

High-throughput

0.407

High

1131471

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

1

High-throughput

0.407

High

1131490

SIAE
Sialate O-acetylesterase

2

0

High-throughput

0.318

High

231044

VEGFD
Vascular endothelial growth factor D

1

0

High-throughput

0.279

Low

282520

PAGE1
P antigen family member 1

1

0

High-throughput

0.279

Low

1036878

SP3
Transcription factor Sp3

1

0

High-throughput

0.279

Low

1101335

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

1131486

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

1131488

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

1

0

High-throughput

0.279

Low

1131497

DKKL1
Dickkopf-like protein 1

1

0

High-throughput

0.279

Low

125950

SMAP
Small acidic protein

1

0

High-throughput

0.265

Low

164687

TNF11
Tumor necrosis factor ligand superfamily member 11

1

0

High-throughput

0.265

Low

299476

CDKA2
Cyclin-dependent kinase 2-associated protein 2

1

0

High-throughput

0.265

Low

1131474

F200C
Protein FAM200C

1

0

High-throughput

0.265

Low

1131483

TNR14
Tumor necrosis factor receptor superfamily member 14

1

0

High-throughput

0.265

Low

828364

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.249

Low

1131473

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.232

Low

1131493

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025