Protein: GEMI8
Gem-associated protein 8 (Gemin-8) (Protein FAM51A1)

Gene: GEMI8, GEMIN8
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q9NWZ8

Gene Ontology (top 5):
GO:0000387 - spliceosomal snRNP assembly
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1436076

GEMI7
Gem-associated protein 7

4

0

High-throughput

0.857

High

1360307

GEMI6
Gem-associated protein 6

3

0

High-throughput

0.816

High

1160594

SMN
Survival motor neuron protein

7

0

Small-scale

0.718

High

974065

RUXF
Small nuclear ribonucleoprotein F

5

3

High-throughput

0.716

High

167128

GEMI2
Gem-associated protein 2

5

0

Small-scale

0.684

High

473131

RU17
U1 small nuclear ribonucleoprotein 70 kDa

5

0

High-throughput

0.682

High

1451588

DDX20
Probable ATP-dependent RNA helicase DDX20

4

0

High-throughput

0.664

High

1451593

STRAP
Serine-threonine kinase receptor-associated protein

4

0

High-throughput

0.664

High

973831

RUXE
Small nuclear ribonucleoprotein E

4

0

High-throughput

0.661

High

1451585

SPN90
NCK-interacting protein with SH3 domain

4

0

High-throughput

0.661

High

574492

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

1

High-throughput

0.628

High

991262

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

1

High-throughput

0.628

High

974207

RUXG
Small nuclear ribonucleoprotein G

2

6

High-throughput

0.611

High

1431466

P2Y12
P2Y purinoceptor 12

3

1

High-throughput

0.609

High

1353055

GEMI5
Gem-associated protein 5

2

0

High-throughput

0.602

High

1451586

KLHL8
Kelch-like protein 8

2

0

High-throughput

0.602

High

1451587

CPNE7
Copine-7

2

0

High-throughput

0.602

High

944574

GEMI4
Gem-associated protein 4

2

0

High-throughput

0.585

High

974678

SMD2
Small nuclear ribonucleoprotein Sm D2

2

0

High-throughput

0.585

High

478230

SNRPA
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.536

High

974855

SMD3
Small nuclear ribonucleoprotein Sm D3

1

3

High-throughput

0.536

High

1451589

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

5

High-throughput

0.536

High

1116056

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.518

High

1365010

TSC1
Hamartin

1

0

High-throughput

0.518

High

480325

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

775341

FUS
RNA-binding protein FUS

1

0

High-throughput

0.513

High

1216411

FAXC
Failed axon connections homolog

1

0

High-throughput

0.513

High

1370603

FGF14
Fibroblast growth factor 14

1

0

High-throughput

0.513

High

1436030

PHAX
Phosphorylated adapter RNA export protein

1

0

High-throughput

0.513

High

1393050

PDLI5
PDZ and LIM domain protein 5

1

0

High-throughput

0.493

High

423313

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1209723

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.480

High

178049

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

5

High-throughput

0.479

High

948175

DJB13
DnaJ homolog subfamily B member 13

1

1

High-throughput

0.479

High

1340521

DNJB8
DnaJ homolog subfamily B member 8

1

1

High-throughput

0.479

High

1451592

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

3

High-throughput

0.479

High

1451594

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

3

High-throughput

0.479

High

129482

MEN1
Menin

1

0

High-throughput

0.458

High

259140

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.458

High

762500

PROF2
Profilin-2

1

0

High-throughput

0.458

High

849042

PTN9
Tyrosine-protein phosphatase non-receptor type 9

1

0

High-throughput

0.458

High

1178424

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1352788

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1364625

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1367416

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1371550

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

0

Small-scale

0.458

High

1393758

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1394627

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

0

Small-scale

0.458

High

1403593

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1451590

MYO6
Unconventional myosin-VI

1

0

High-throughput

0.458

High

71621

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

6

High-throughput

0.445

High

166431

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

1

High-throughput

0.445

High

171598

S27A2
Long-chain fatty acid transport protein 2

1

1

High-throughput

0.445

High

1234982

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.445

High

1337978

ZNT7
Zinc transporter 7

1

1

High-throughput

0.445

High

1208414

WIPI1
WD repeat domain phosphoinositide-interacting protein 1

1

0

High-throughput

0.438

High

1317007

FAM9B
Protein FAM9B

1

0

High-throughput

0.426

High

1449952

S39A9
Zinc transporter ZIP9

1

0

High-throughput

0.426

High

1243670

S27A1
Long-chain fatty acid transport protein 1

1

1

High-throughput

0.407

High

683350

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.279

Low

1132585

FXYD3
FXYD domain-containing ion transport regulator 3

1

0

High-throughput

0.279

Low

1249861

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.279

Low

1291695

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1330751

SIGL1
SIGLEC family-like protein 1

1

0

High-throughput

0.279

Low

1090309

ELAV2
ELAV-like protein 2

1

0

High-throughput

0.268

Low

47425

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.257

Low

124518

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

1286932

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.249

Low

50714

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

835407

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

0

High-throughput

0.232

Low

1101682

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.232

Low

1253207

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

1451591

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025