Protein: ORC2
Origin recognition complex subunit 2 (Origin recognition complex 71 kDa subunit)

Gene: ORC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 60
UniProt ID: P32833

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0003682 - chromatin binding
GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

698724

ORC5
Origin recognition complex subunit 5

13

4

Small-scale

0.981

High

698730

ORC1
Origin recognition complex subunit 1

13

13

Small-scale

0.978

High

698732

ORC4
Origin recognition complex subunit 4

10

13

Small-scale

0.972

High

447789

CDC6
Cell division control protein 6

7

14

Small-scale

0.957

High

698731

ORC3
Origin recognition complex subunit 3

13

0

Small-scale

0.932

High

698716

ORC6
Origin recognition complex subunit 6

11

0

Small-scale

0.929

High

698709

ORC2
Origin recognition complex subunit 2

2

4

Small-scale

0.754

High

339534

CDK1
Cyclin-dependent kinase 1

5

6

Small-scale

0.718

High

698713

PCH2
Pachytene checkpoint protein 2

1

0

Small-scale

0.687

High

687527

DBF4
DDK kinase regulatory subunit DBF4

3

0

Small-scale

0.632

High

667558

MCM2
DNA replication licensing factor MCM2

2

8

Small-scale

0.629

High

698741

HAT1
Histone acetyltransferase type B catalytic subunit

3

0

Small-scale

0.622

High

355841

H2B2
Histone H2B.2

2

5

High-throughput

0.601

High

392364

H2A2
Histone H2A.2

2

1

High-throughput

0.601

High

673192

CGS5
S-phase entry cyclin-5

2

4

Small-scale

0.595

High

688629

MCM10
Minichromosome maintenance protein 10

2

3

Small-scale

0.595

High

356358

H4
Histone H4

2

2

High-throughput

0.588

High

698718

FKH1
Fork head protein homolog 1

2

5

Small-scale

0.584

High

698734

CDC14
Tyrosine-protein phosphatase CDC14

1

1

Small-scale

0.573

High

355418

H2B1
Histone H2B.1

2

5

High-throughput

0.571

High

493527

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.552

High

510709

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

698740

CLF1
Pre-mRNA-splicing factor CLF1

1

0

Small-scale

0.549

High

698719

MAD1
Spindle assembly checkpoint component MAD1

1

2

Small-scale

0.541

High

698727

PESC
Pescadillo homolog

1

0

Small-scale

0.537

High

608741

CHL1
ATP-dependent DNA helicase CHL1

1

0

Small-scale

0.529

High

698723

CDT1
Cell division cycle protein CDT1

1

0

Small-scale

0.529

High

698726

THG1
tRNA(His) guanylyltransferase

1

0

Small-scale

0.529

High

698735

SPP1
COMPASS component SPP1

1

0

Small-scale

0.529

High

516861

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.518

High

620009

MPIP
M-phase inducer phosphatase

1

0

Small-scale

0.518

High

698736

HMO1
High mobility group protein 1

1

3

High-throughput

0.515

High

376700

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.513

High

622155

MCM3
DNA replication licensing factor MCM3

1

8

Small-scale

0.501

High

667842

MCM5
Minichromosome maintenance protein 5

1

6

Small-scale

0.501

High

693690

IME2
Meiosis induction protein kinase IME2/SME1

1

6

Small-scale

0.501

High

698714

MCM7
DNA replication licensing factor MCM7

1

7

Small-scale

0.501

High

698738

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.493

High

412541

CDC7
Cell division control protein 7

1

7

Small-scale

0.481

High

698720

FKH2
Fork head protein homolog 2

1

5

Small-scale

0.479

High

698733

H3
Histone H3

1

7

Small-scale

0.479

High

698725

SLD3
DNA replication regulator SLD3

1

0

Small-scale

0.460

High

698728

IPI3
Pre-rRNA-processing protein IPI3

1

0

Small-scale

0.460

High

698737

NOC3
Nucleolar complex-associated protein 3

1

0

Small-scale

0.460

High

600268

SIR1
Regulatory protein SIR1

1

0

Small-scale

0.458

High

661728

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

698710

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

698711

BMH2
Protein BMH2

1

0

Small-scale

0.458

High

698712

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

698715

NU170
Nucleoporin NUP170

1

0

High-throughput

0.458

High

698721

SUM1
Suppressor of mar1-1 protein

1

0

Small-scale

0.458

High

698729

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

490722

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

694364

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

698717

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

698742

RLF2
Chromatin assembly factor 1 subunit p90

1

1

High-throughput

0.445

High

698739

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low

404533

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.232

Low

698722

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024