Protein: STE12
Protein STE12

Gene: STE12
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: P13574

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000747 - conjugation with cellular fusion
GO:0001403 - invasive growth in response to glucose limitation
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

564635

KSS1
Mitogen-activated protein kinase KSS1

9

3

Small-scale

0.756

High

564672

DIG1
Down-regulator of invasive growth 1

12

0

Small-scale

0.728

High

564675

DIG2
Down-regulator of invasive growth 2

9

0

Small-scale

0.725

High

564639

TEC1
Ty transcription activator TEC1

8

0

Small-scale

0.722

High

564638

FUS3
Mitogen-activated protein kinase FUS3

3

2

Small-scale

0.664

High

548746

MCM1
Pheromone receptor transcription factor

3

0

Small-scale

0.636

High

564646

IMB3
Importin subunit beta-3

2

0

Small-scale

0.592

High

515394

MTAL1
Mating-type protein ALPHA1

2

0

Small-scale

0.575

High

564645

MET14
Karyogamy protein KAR4

2

0

Small-scale

0.561

High

564669

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

4

High-throughput

0.554

High

564679

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.541

High

564654

MSA2
Putative transcriptional activator MSA2

1

0

Small-scale

0.537

High

564682

MSA1
G1-specific transcription factors activator MSA1

1

0

Small-scale

0.537

High

564650

SPT7
SAGA complex subunit SPT7

1

1

High-throughput

0.536

High

564653

KDX1
Serine/threonine-protein kinase KDX1

1

2

High-throughput

0.536

High

416851

CDC25
Cell division control protein 25

1

0

High-throughput

0.518

High

564670

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.518

High

564647

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

0

High-throughput

0.513

High

564656

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

0

High-throughput

0.513

High

564671

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.513

High

564673

SGF11
SAGA complex subunit SGF11

1

0

High-throughput

0.513

High

564674

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.513

High

564686

SUS1
SAGA complex subunit SUS1

1

0

High-throughput

0.513

High

564659

SSN3
Meiotic mRNA stability protein kinase SSN3

1

0

Small-scale

0.494

High

564657

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.493

High

564642

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

0

Small-scale

0.480

High

564644

MAS5
Mitochondrial protein import protein MAS5

1

1

Small-scale

0.479

High

564663

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

Small-scale

0.479

High

564667

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

564685

AHC1
Protein AHC1

1

0

Small-scale

0.460

High

513321

RL23B
Large ribosomal subunit protein uL14B

1

0

Small-scale

0.458

High

564636

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.458

High

564648

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.458

High

564651

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

564652

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

564655

RNZ
Ribonuclease Z

1

0

High-throughput

0.458

High

564662

FLO8
Transcriptional activator FLO8

1

0

Small-scale

0.458

High

564666

SCW4
Probable family 17 glucosidase SCW4

1

0

Small-scale

0.458

High

564668

ORC1
Origin recognition complex subunit 1

1

0

Small-scale

0.458

High

564676

MSS11
Transcription activator MSS11

1

0

Small-scale

0.458

High

564677

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

564678

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

564680

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

564681

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

564683

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

564684

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

522902

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

525792

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

564643

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

531223

METK1
S-adenosylmethionine synthase 1

1

1

Small-scale

0.437

High

564640

METK2
S-adenosylmethionine synthase 2

1

1

Small-scale

0.437

High

564641

RS3A2
Small ribosomal subunit protein eS1B

1

1

Small-scale

0.437

High

564649

RS3A1
Small ribosomal subunit protein eS1A

1

1

Small-scale

0.437

High

380940

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

448123

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

543652

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

564658

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.426

High

564664

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.426

High

564665

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.426

High

564661

RPN3
26S proteasome regulatory subunit RPN3

1

0

High-throughput

0.269

Low

394172

EF1A
Elongation factor 1-alpha

1

0

Small-scale

0.249

Low

513448

RL1A
Large ribosomal subunit protein uL1A

1

0

Small-scale

0.249

Low

564637

VATB
V-type proton ATPase subunit B

1

0

Small-scale

0.249

Low

564660

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025