Protein: EAP1
Protein EAP1 (eIF4E-associated protein 1)

Gene: EAP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 161
UniProt ID: P36041

Gene Ontology (top 5):
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0003729 - mRNA binding
GO:0005524 - ATP binding
GO:0006402 - mRNA catabolic process
GO:0008190 - eukaryotic initiation factor 4E binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

453934

IF4E
Eukaryotic translation initiation factor 4E

9

0

Small-scale

0.719

High

544446

SSB1
Ribosome-associated molecular chaperone SSB1

4

1

High-throughput

0.666

High

747797

SMY2
Protein SMY2

4

1

Small-scale

0.617

High

780021

DHH1
ATP-dependent RNA helicase DHH1

2

1

Small-scale

0.584

High

679566

CDC48
Cell division control protein 48

2

0

High-throughput

0.576

High

741336

HSP7F
Heat shock protein homolog SSE1

2

1

High-throughput

0.571

High

645368

XRN1
5'-3' exoribonuclease 1

2

0

Small-scale

0.559

High

780048

CBK1
Serine/threonine-protein kinase CBK1

1

0

High-throughput

0.513

High

780023

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.493

High

656744

KC12
Casein kinase I homolog 2

1

0

High-throughput

0.486

High

409714

RL24A
Large ribosomal subunit protein eL24A

1

1

High-throughput

0.479

High

444487

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.479

High

517980

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.479

High

632656

DBP4
ATP-dependent RNA helicase HCA4

1

2

High-throughput

0.479

High

663664

RL24B
Large ribosomal subunit protein eL24B

1

1

High-throughput

0.479

High

676717

GBP2
Serine/arginine

1

1

High-throughput

0.479

High

676911

SRO9
RNA-binding protein SRO9

1

1

High-throughput

0.479

High

688998

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.479

High

689193

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.479

High

740863

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

780009

NOP4
Nucleolar protein 4

1

1

High-throughput

0.479

High

780012

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.479

High

780014

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

780018

MPT5
Suppressor protein MPT5

1

2

Small-scale

0.479

High

780022

RBG1
Ribosome-interacting GTPase 1

1

1

High-throughput

0.479

High

780026

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.479

High

780037

JSN1
Protein JSN1

1

2

Small-scale

0.479

High

780041

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.479

High

780042

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.479

High

780053

NOP3
Serine/arginine

1

2

High-throughput

0.479

High

780070

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.479

High

780072

PUF2
mRNA-binding protein PUF2

1

2

Small-scale

0.479

High

780071

RIO1
Serine/threonine-protein kinase RIO1

1

0

Small-scale

0.460

High

403452

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.458

High

430830

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

High-throughput

0.458

High

438668

SC160
Protein SCP160

1

0

Small-scale

0.458

High

448954

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.458

High

510380

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

515239

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.458

High

541154

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

579194

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

666433

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

688862

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.458

High

721602

RENT1
ATP-dependent helicase NAM7

1

0

High-throughput

0.458

High

751955

LHP1
La protein homolog

1

0

High-throughput

0.458

High

780010

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.458

High

780015

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.458

High

780016

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.458

High

780019

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.458

High

780020

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.458

High

780024

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.458

High

780034

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

High-throughput

0.458

High

780035

SCD6
Protein SCD6

1

0

Small-scale

0.458

High

780043

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.458

High

780045

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

780051

ACAC
Acetyl-CoA carboxylase

1

0

High-throughput

0.458

High

780059

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.458

High

780061

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

0

Small-scale

0.458

High

780067

VTS1
RNA-binding protein VTS1

1

0

Small-scale

0.458

High

427222

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.437

High

433004

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.437

High

433566

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

433997

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.437

High

601017

RL8A
Large ribosomal subunit protein eL8A

1

2

High-throughput

0.437

High

655433

RS3A2
Small ribosomal subunit protein eS1B

1

1

High-throughput

0.437

High

689378

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

712538

RL8B
Large ribosomal subunit protein eL8B

1

2

High-throughput

0.437

High

738199

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

2

High-throughput

0.437

High

750057

MRT4
Ribosome assembly factor MRT4

1

1

High-throughput

0.437

High

753294

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

780031

RL33B
Large ribosomal subunit protein eL33B

1

1

High-throughput

0.437

High

780038

RS7B
Small ribosomal subunit protein eS7B

1

1

High-throughput

0.437

High

780044

RL26B
Large ribosomal subunit protein uL24B

1

1

High-throughput

0.437

High

780055

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.437

High

780056

SYH1
SMY2 homolog 2

1

1

Small-scale

0.437

High

780057

NOG1
Nucleolar GTP-binding protein 1

1

1

High-throughput

0.437

High

780058

RT10
Small ribosomal subunit protein uS10m

1

1

High-throughput

0.437

High

526388

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

776552

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.282

High

454431

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.279

Low

721839

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

780033

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.279

Low

780060

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.269

Low

780064

ESC8
Protein ESC8

1

0

High-throughput

0.269

Low

780030

MAD2
Mitotic spindle checkpoint component MAD2

1

0

High-throughput

0.251

Low

154150

RL36B
Large ribosomal subunit protein eL36B

1

0

High-throughput

0.249

Low

381487

H2B2
Histone H2B.2

1

0

High-throughput

0.249

Low

382028

H4
Histone H4

1

0

High-throughput

0.249

Low

383288

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.249

Low

383630

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

410054

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

419696

H2A2
Histone H2A.2

1

0

High-throughput

0.249

Low

432539

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.249

Low

432824

RL9A
Large ribosomal subunit protein uL6A

1

0

High-throughput

0.249

Low

433181

RL17A
Large ribosomal subunit protein uL22A

1

0

High-throughput

0.249

Low

434351

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.249

Low

434544

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.249

Low

434998

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

435546

RS9B
Small ribosomal subunit protein uS4B

1

0

High-throughput

0.249

Low

436378

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.249

Low

502973

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

503777

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.249

Low

504149

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

511170

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

511398

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.249

Low

511649

RS23B
Small ribosomal subunit protein uS12B

1

0

High-throughput

0.249

Low

511770

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.249

Low

512055

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.249

Low

585254

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.249

Low

780011

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.249

Low

780013

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.249

Low

780017

STM1
Suppressor protein STM1

1

0

High-throughput

0.249

Low

780025

PXP1
2-hydroxyacyl-CoA lyase

1

0

High-throughput

0.249

Low

780027

MLP2
Protein MLP2

1

0

High-throughput

0.249

Low

780028

RL34B
Large ribosomal subunit protein eL34B

1

0

High-throughput

0.249

Low

780029

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

780032

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

780036

RSSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.249

Low

780039

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

780040

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.249

Low

780046

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

High-throughput

0.249

Low

780047

FMP41
Oxaloacetate tautomerase FMP41, mitochondrial

1

0

High-throughput

0.249

Low

780049

YNL5
Uncharacterized vacuolar membrane protein YNL115C

1

0

High-throughput

0.249

Low

780050

AP2S
AP-2 complex subunit sigma

1

0

High-throughput

0.249

Low

780052

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low

780054

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

780062

NOP6
Nucleolar protein 6

1

0

High-throughput

0.249

Low

780063

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.249

Low

780065

NOP12
Nucleolar protein 12

1

0

High-throughput

0.249

Low

780066

PUS7
Multisubstrate pseudouridine synthase 7

1

0

High-throughput

0.249

Low

780068

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

780069

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

0

High-throughput

0.249

Low

780073

RLM1
Transcription factor RLM1

1

0

High-throughput

0.249

Low

780074

UTP23
rRNA-processing protein UTP23

1

0

High-throughput

0.249

Low

780075

TCB1
Tricalbin-1

1

0

High-throughput

0.249

Low

780076

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.249

Low

780077

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.249

Low

780078

RL11B
Large ribosomal subunit protein uL5B

1

0

High-throughput

0.249

Low

780079

RS25A
Small ribosomal subunit protein eS25A

1

0

High-throughput

0.249

Low

512369

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

512935

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

513349

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.249

Low

513481

RL1A
Large ribosomal subunit protein uL1A

1

0

High-throughput

0.249

Low

513666

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

513847

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.249

Low

513978

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.249

Low

514124

RS16B
Small ribosomal subunit protein uS9B

1

0

High-throughput

0.249

Low

514262

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.249

Low

514570

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

515075

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

557588

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

0

High-throughput

0.249

Low

569755

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.249

Low

569967

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

575433

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.249

Low

582444

SEC23
Protein transport protein SEC23

1

0

High-throughput

0.249

Low

674542

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

677347

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

700229

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.249

Low

706769

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

734071

EF2
Elongation factor 2

1

0

High-throughput

0.249

Low

780008

PAM1
Protein PAM1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025