Protein: EAF1
Chromatin modification-related protein EAF1 (ESA1-associated factor 1) (Vacuolar import and degradation protein 21)

Gene: EAF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: Q06337

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006325 - chromatin organization
GO:0006351 - DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

805222

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

7

1

Small-scale

0.960

High

1010212

ARP4
Actin-related protein 4

7

1

Small-scale

0.958

High

918175

SWC4
SWR1-complex protein 4

9

0

Small-scale

0.921

High

948662

ACT
Actin

6

0

Small-scale

0.878

High

849811

EPL1
Enhancer of polycomb-like protein 1

18

1

Small-scale

0.764

High

1054842

ESA1
Histone acetyltransferase ESA1

16

1

Small-scale

0.761

High

816627

EAF5
Chromatin modification-related protein EAF5

9

0

Small-scale

0.722

High

924902

AF9
Protein AF-9 homolog

8

0

Small-scale

0.716

High

1054844

EAF3
Chromatin modification-related protein EAF3

8

0

Small-scale

0.713

High

805140

YNG2
Chromatin modification-related protein YNG2

7

0

Small-scale

0.712

High

865850

EAF6
Chromatin modification-related protein EAF6

5

0

Small-scale

0.684

High

924590

EAF7
Chromatin modification-related protein EAF7

5

0

Small-scale

0.684

High

963733

H3
Histone H3

3

0

Small-scale

0.650

High

828512

SA185
SIT4-associating protein SAP185

2

0

High-throughput

0.602

High

382361

H4
Histone H4

2

0

Small-scale

0.560

High

402120

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

0

Small-scale

0.559

High

525231

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.536

High

546373

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.536

High

626540

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.513

High

722276

XPO1
Exportin-1

1

0

High-throughput

0.513

High

737950

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.513

High

1054839

EAF1
Chromatin modification-related protein EAF1

1

0

Small-scale

0.513

High

925075

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

639515

RE107
Recombination protein 107

1

0

High-throughput

0.460

High

665856

KPC1
Protein kinase C-like 1

1

0

High-throughput

0.460

High

594581

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.458

High

647842

RFA1
Replication factor A protein 1

1

0

Small-scale

0.458

High

735174

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

741128

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

748056

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

764011

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

800768

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.458

High

826854

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

836658

GLDS1
Protein GDS1

1

0

High-throughput

0.458

High

916950

VID30
GID complex subunit 1

1

0

Small-scale

0.458

High

1044763

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

527743

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

671152

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

676375

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

742457

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

742953

HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

0.445

High

754189

MSN2
Zinc finger protein MSN2

1

1

High-throughput

0.445

High

754249

MSN4
Zinc finger protein MSN4

1

1

High-throughput

0.445

High

811498

XDJ1
DnaJ protein homolog XDJ1

1

2

High-throughput

0.445

High

819865

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

1035334

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

1

High-throughput

0.445

High

792963

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

381274

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

393370

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

448224

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

645647

AFT1
Iron-regulated transcriptional activator AFT1

1

0

High-throughput

0.426

High

653904

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

804479

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

1042377

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.426

High

1054841

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

1054843

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.426

High

758151

CASP
Protein CASP

1

0

High-throughput

0.251

Low

813859

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

816004

VAC8
Vacuolar protein 8

1

0

Small-scale

0.251

Low

866198

SGM1
Protein SGM1

1

0

High-throughput

0.251

Low

796892

GID4
GID complex substrate-recognition subunit 4

1

0

Small-scale

0.249

Low

815239

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.249

Low

826377

SGN1
RNA-binding protein SGN1

1

0

Small-scale

0.249

Low

1046040

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

752761

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

810903

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low

816748

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

863750

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

865080

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

1046608

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low

1046750

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low

1054840

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025