Protein: TBF1
Protein TBF1 (TBF-alpha) (TTAGGG repeat-binding factor 1)

Gene: TBF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: Q02457

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001015 - snoRNA transcription by RNA polymerase II
GO:0003691 - double-stranded telomeric DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1036948

VID22
Vacuolar import and degradation protein 22

5

1

Small-scale

0.712

High

918575

ENV11
Late endosome and vacuole interface protein 11

4

1

Small-scale

0.681

High

1036945

TBF1
Protein TBF1

1

1

Small-scale

0.618

High

763979

SPT10
Protein SPT10

1

0

High-throughput

0.586

High

646508

RAD53
Serine/threonine-protein kinase RAD53

2

0

High-throughput

0.585

High

381220

H2B1
Histone H2B.1

2

0

High-throughput

0.576

High

858458

TAF1
Transcription initiation factor TFIID subunit 1

2

0

High-throughput

0.563

High

550075

RAP1
DNA-binding protein RAP1

1

0

High-throughput

0.546

High

419844

H2A2
Histone H2A.2

1

0

High-throughput

0.513

High

792914

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.513

High

735541

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.501

High

518113

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.480

High

594525

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

647190

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

671037

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

707949

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735124

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

924998

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

1036947

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

1036951

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

524894

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527470

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

545960

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

742214

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

819562

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

1036953

H2AZ
Histone H2A.Z

1

1

High-throughput

0.445

High

448213

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

548793

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.426

High

597249

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

671550

SWI4
Regulatory protein SWI4

1

0

High-throughput

0.426

High

736708

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

738772

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

High-throughput

0.426

High

752985

IXR1
Intrastrand cross-link recognition protein

1

0

High-throughput

0.426

High

781788

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

800752

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.426

High

1035315

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

0

High-throughput

0.426

High

1036946

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.426

High

1036949

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

1036952

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

780586

CUE2
Endonuclease CUE2

1

0

High-throughput

0.265

Low

745286

ELM1
Serine/threonine-protein kinase ELM1

1

0

High-throughput

0.261

Low

579926

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

1036950

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

427038

FUR4
Uracil permease

1

0

High-throughput

0.232

Low

752635

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

866152

CAF17
Iron-sulfur cluster assembly factor IBA57, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025