Protein: RSC58
Chromatin structure-remodeling complex protein RSC58 (Remodel the structure of chromatin complex subunit 58)

Gene: RSC58
Organism: Saccharomyces cerevisiae S288C
Interactions: 153
UniProt ID: Q07979

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0006337 - nucleosome disassembly
GO:0006338 - chromatin remodeling
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743147

STH1
Nuclear protein STH1/NPS1

12

2

Small-scale

0.979

High

1055384

RSC2
Chromatin structure-remodeling complex subunit RSC2

11

4

Small-scale

0.974

High

1035341

RSC4
Chromatin structure-remodeling complex subunit RSC4

8

5

Small-scale

0.966

High

918530

RSC1
Chromatin structure-remodeling complex subunit RSC1

6

6

Small-scale

0.938

High

823053

ATAD2
ATPase histone chaperone YTA7

4

0

Small-scale

0.823

High

1061376

RSC58
Chromatin structure-remodeling complex protein RSC58

3

0

High-throughput

0.804

High

777131

BDF1
Bromodomain-containing factor 1

2

3

High-throughput

0.737

High

1056352

RSC3
Chromatin structure-remodeling complex protein RSC3

6

1

High-throughput

0.732

High

1061388

ARP7
Actin-related protein 7

6

1

High-throughput

0.732

High

1050600

ARP9
Actin-like protein ARP9

6

1

High-throughput

0.729

High

850590

RSC8
Chromatin structure-remodeling complex protein RSC8

8

0

Small-scale

0.716

High

678350

RSC6
Chromatin structure-remodeling complex protein RSC6

7

0

Small-scale

0.713

High

745622

RSC7
Chromatin structure-remodeling complex subunit RSC7

6

0

High-throughput

0.701

High

1041007

RSC9
Chromatin structure-remodeling complex subunit RSC9

6

0

High-throughput

0.701

High

919696

RT102
Regulator of Ty1 transposition protein 102

6

0

High-throughput

0.699

High

794229

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

4

1

High-throughput

0.687

High

419893

H2A2
Histone H2A.2

5

0

High-throughput

0.679

High

1054040

SFH1
Chromatin structure-remodeling complex subunit SFH1

5

0

Small-scale

0.679

High

1061394

HTL1
High temperature lethal protein 1

5

0

High-throughput

0.676

High

804009

RSC30
Chromatin structure-remodeling complex protein RSC30

3

1

High-throughput

0.650

High

382382

H4
Histone H4

4

0

Small-scale

0.648

High

963761

H3
Histone H3

4

0

Small-scale

0.648

High

1059306

BDF2
Bromodomain-containing factor 2

1

1

High-throughput

0.618

High

547891

NHP6B
Non-histone chromosomal protein 6B

2

1

High-throughput

0.588

High

489008

SWI6
Regulatory protein SWI6

2

1

Small-scale

0.576

High

1042387

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.575

High

381293

H2B1
Histone H2B.1

2

1

High-throughput

0.571

High

381655

H2B2
Histone H2B.2

2

1

High-throughput

0.571

High

734484

BTAF1
TATA-binding protein-associated factor MOT1

2

3

Small-scale

0.571

High

826888

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

527838

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

561541

TBP
TATA-box-binding protein

2

0

High-throughput

0.547

High

739795

SPT16
FACT complex subunit SPT16

2

0

High-throughput

0.547

High

764020

SPT10
Protein SPT10

2

0

High-throughput

0.547

High

796041

LDB7
Chromatin structure-remodeling complex protein RSC14

2

0

High-throughput

0.547

High

1046945

POB3
FACT complex subunit POB3

2

0

High-throughput

0.547

High

1061381

IOC2
ISWI one complex protein 2

2

0

High-throughput

0.547

High

736741

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.546

High

546511

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

584457

IDI1
Isopentenyl-diphosphate delta-isomerase

1

0

High-throughput

0.518

High

1040450

UME1
Transcriptional regulatory protein UME1

1

0

High-throughput

0.518

High

1061383

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.513

High

435399

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

449018

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.458

High

594602

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

708359

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735196

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

740436

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.458

High

745897

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

748080

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

763383

TAF14
Transcription initiation factor TFIID subunit 14

1

0

Small-scale

0.458

High

792278

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.458

High

795654

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

0

High-throughput

0.458

High

863167

FYV8
Protein FYV8

1

0

High-throughput

0.458

High

924428

CBK1
Serine/threonine-protein kinase CBK1

1

0

High-throughput

0.458

High

1054856

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

1059345

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.458

High

1061377

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

Small-scale

0.458

High

1061378

SGO1
Shugoshin

1

0

High-throughput

0.458

High

1061382

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

1061384

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.458

High

1061391

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

1061393

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

525342

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

547833

NHP6A
Non-histone chromosomal protein 6A

1

1

High-throughput

0.445

High

664471

MCM3
DNA replication licensing factor MCM3

1

2

High-throughput

0.445

High

671564

SWI4
Regulatory protein SWI4

1

1

High-throughput

0.445

High

713044

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.445

High

713310

MCM5
Minichromosome maintenance protein 5

1

2

High-throughput

0.445

High

742531

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

754190

MSN2
Zinc finger protein MSN2

1

1

High-throughput

0.445

High

754252

MSN4
Zinc finger protein MSN4

1

1

High-throughput

0.445

High

917070

MCM6
DNA replication licensing factor MCM6

1

1

High-throughput

0.445

High

917330

INO80
Chromatin-remodeling ATPase INO80

1

2

High-throughput

0.445

High

1044485

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.445

High

1051137

SWR1
Helicase SWR1

1

1

High-throughput

0.445

High

1061387

ARP8
Actin-like protein ARP8

1

1

High-throughput

0.445

High

1061389

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.445

High

1061392

H2AZ
Histone H2A.Z

1

1

High-throughput

0.445

High

805709

YHS2
MIP18 family protein YHR122W

1

0

High-throughput

0.438

High

359362

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

402135

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.426

High

448231

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

548804

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.426

High

550084

RAP1
DNA-binding protein RAP1

1

0

High-throughput

0.426

High

650024

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

671183

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

694660

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.426

High

736051

SP110
Spindle pole body component 110

1

0

High-throughput

0.426

High

737685

HIR2
Protein HIR2

1

0

High-throughput

0.426

High

744351

CHD1
Chromo domain-containing protein 1

1

0

High-throughput

0.426

High

744583

T2AG
Transcription initiation factor IIA subunit 2

1

0

High-throughput

0.426

High

757776

SAS3
Histone acetyltransferase SAS3

1

0

High-throughput

0.426

High

781812

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

794008

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

0

High-throughput

0.426

High

805228

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

0

High-throughput

0.426

High

805759

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.426

High

807160

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

807281

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.426

High

820445

RT106
Histone chaperone RTT106

1

0

High-throughput

0.426

High

850386

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.426

High

916608

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

0

High-throughput

0.426

High

921172

H1
Histone H1

1

0

High-throughput

0.426

High

925101

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.426

High

948673

ACT
Actin

1

0

High-throughput

0.426

High

1026841

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

1036949

TBF1
Protein TBF1

1

0

High-throughput

0.426

High

1040031

HOS3
Histone deacetylase HOS3

1

0

High-throughput

0.426

High

1043982

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

0

High-throughput

0.426

High

1050227

TRI1
Protein TRI1

1

0

High-throughput

0.426

High

1050239

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.426

High

1054841

EAF1
Chromatin modification-related protein EAF1

1

0

High-throughput

0.426

High

1055425

IWS1
Transcription factor SPN1

1

0

High-throughput

0.426

High

1061380

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

1

0

High-throughput

0.426

High

1061385

NTO1
NuA3 HAT complex component NTO1

1

0

High-throughput

0.426

High

1061386

IES3
Ino eighty subunit 3

1

0

High-throughput

0.426

High

1061390

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

823175

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.282

High

850354

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

0

High-throughput

0.282

High

1056527

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.279

Low

149981

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

383921

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

410365

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433876

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

436200

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

455291

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

504443

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

512683

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

513251

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

514862

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

674865

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

689694

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

747610

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

778563

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

802417

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

874560

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

1033597

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

1061379

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

1018182

YD413
Putative uncharacterized protein YDR413C

1

0

High-throughput

0.238

Low

1035145

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

149231

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.232

Low

358351

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

365207

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

365701

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.232

Low

368068

ENO2
Enolase 2

1

0

High-throughput

0.232

Low

453825

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

592538

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

810776

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

811182

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

815072

SNF7
Vacuolar-sorting protein SNF7

1

0

High-throughput

0.232

Low

826505

DJP1
DnaJ-like protein 1

1

0

High-throughput

0.232

Low

864339

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025