Protein: SEN15
tRNA-splicing endonuclease subunit SEN15 (Splicing endonuclease of 15 kDa) (tRNA-intron endonuclease SEN15)

Gene: SEN15
Organism: Saccharomyces cerevisiae S288C
Interactions: 83
UniProt ID: Q04675

Gene Ontology (top 5):
GO:0000214 - tRNA-intron endonuclease complex
GO:0000379 - tRNA-type intron splice site recognition and cleavage
GO:0003676 - nucleic acid binding
GO:0005741 - mitochondrial outer membrane
GO:0012505 - endomembrane system

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

598486

SEN2
tRNA-splicing endonuclease subunit SEN2

3

0

Small-scale

0.804

High

813674

SEN34
tRNA-splicing endonuclease subunit SEN34

2

0

Small-scale

0.759

High

1039090

SEN54
tRNA-splicing endonuclease subunit SEN54

2

0

Small-scale

0.559

High

668954

ERG6
Sterol 24-C-methyltransferase ERG6

1

1

High-throughput

0.536

High

918681

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.536

High

1047348

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.536

High

598914

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

High-throughput

0.513

High

455591

SYSC
Serine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.489

High

802975

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

1

High-throughput

0.489

High

919614

6PGD2
6-phosphogluconate dehydrogenase, decarboxylating 2

1

1

High-throughput

0.489

High

368753

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.479

High

416477

HXKA
Hexokinase-1

1

1

High-throughput

0.457

High

452971

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.457

High

531402

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.457

High

592495

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.457

High

607790

HXKG
Glucokinase-1

1

1

High-throughput

0.457

High

621407

METK2
S-adenosylmethionine synthase 2

1

1

High-throughput

0.457

High

709975

BMH1
Protein BMH1

1

1

High-throughput

0.457

High

760348

BMH2
Protein BMH2

1

1

High-throughput

0.457

High

856565

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.457

High

926282

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

1

High-throughput

0.457

High

361453

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.279

Low

382335

H4
Histone H4

1

0

High-throughput

0.279

Low

416155

SYTC
Threonine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.279

Low

432364

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.279

Low

438772

SC160
Protein SCP160

1

0

High-throughput

0.279

Low

453204

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.279

Low

453999

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.279

Low

455524

PMM
Phosphomannomutase

1

0

High-throughput

0.279

Low

464341

OAT
Ornithine aminotransferase

1

0

High-throughput

0.279

Low

475141

CYAA
Adenylate cyclase

1

0

High-throughput

0.279

Low

488631

RIR2
Ribonucleoside-diphosphate reductase small chain 1

1

0

High-throughput

0.279

Low

518388

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.279

Low

536165

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.279

Low

576006

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.279

Low

585183

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.279

Low

622394

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.279

Low

628093

FKBP
FK506-binding protein 1

1

0

High-throughput

0.279

Low

645858

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.279

Low

649521

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.279

Low

660240

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.279

Low

673360

GLRX1
Glutaredoxin-1

1

0

High-throughput

0.279

Low

726591

VATC
V-type proton ATPase subunit C

1

0

High-throughput

0.279

Low

733779

ACH1
Acetyl-CoA hydrolase

1

0

High-throughput

0.279

Low

740694

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.279

Low

751167

AFR1
Protein AFR1

1

0

High-throughput

0.279

Low

751654

NTF2
Nuclear transport factor 2

1

0

High-throughput

0.279

Low

775989

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.279

Low

779103

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.279

Low

779192

NDK
Nucleoside diphosphate kinase

1

0

High-throughput

0.279

Low

792372

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.279

Low

793108

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

796181

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.279

Low

815750

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.279

Low

816551

SNU13
13 kDa ribonucleoprotein-associated protein

1

0

High-throughput

0.279

Low

823116

PDAT
Phospholipid:diacylglycerol acyltransferase

1

0

High-throughput

0.279

Low

825995

PRM2
Pheromone-regulated membrane protein 2

1

0

High-throughput

0.279

Low

858130

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.279

Low

858291

ARC1
tRNA-aminoacylation cofactor ARC1

1

0

High-throughput

0.279

Low

925482

EF3B
Elongation factor 3B

1

0

High-throughput

0.279

Low

932655

ERG13
Hydroxymethylglutaryl-CoA synthase

1

0

High-throughput

0.279

Low

1038037

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

0

High-throughput

0.279

Low

1040601

COFI
Cofilin

1

0

High-throughput

0.279

Low

1043113

RSN1
Uncharacterized protein RSN1

1

0

High-throughput

0.279

Low

1043352

OYE2
NADPH dehydrogenase 2

1

0

High-throughput

0.279

Low

1043593

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.279

Low

1045054

TSA2
Peroxiredoxin TSA2

1

0

High-throughput

0.279

Low

1047349

WTM1
Transcriptional modulator WTM1

1

0

High-throughput

0.279

Low

1047345

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.265

Low

367401

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.261

Low

394897

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.261

Low

405144

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

408351

GAL1
Galactokinase

1

0

High-throughput

0.261

Low

484795

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

555154

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

613633

ADT2
ADP,ATP carrier protein 2

1

0

High-throughput

0.261

Low

661693

MPCP
Mitochondrial phosphate carrier protein

1

0

High-throughput

0.261

Low

680054

CDC48
Cell division control protein 48

1

0

High-throughput

0.261

Low

746309

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.261

Low

948653

ACT
Actin

1

0

High-throughput

0.261

Low

1047347

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

1047346

PSR1
Phosphatase PSR1

1

0

Small-scale

0.251

Low

792942

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025