HitPredict

Interactor 1: MUS81 (P87231)
Crossover junction endonuclease mus81 (EC 3.1.22.-)
Gene: MUS81

Interactor 2: CDS1 (Q09170)
Serine/threonine-protein kinase cds1 (EC 2.7.11.1) (Checkpoint kinase cds1)
Gene: CDS1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	15805465, 11073977, 26771498, 21084840
Identification Methods	affinity chromatography technology, pull down, two hybrid, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031573 - mitotic intra-S DNA damage checkpoint signaling GO:0033314 - mitotic DNA replication checkpoint signaling
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 608 Sp			1 460
+	Sp
		953485 MUS81_SCHPO (1-608): 0: 751: 100.00		MEK1_SCHPO (60-443): 3.51e-120: 359: 31.47
+	Sc
		606133 MUS81_YEAST (7-604): 0: 544: 27.12		RAD53_YEAST (5-434): 8.91e-131: 399: 33.33
+	Hs
		331326 MUS81_HUMAN (3-607): 0: 548: 21.60		CHK2_HUMAN (36-453): 3.16e-132: 394: 33.33