Protein: DUSTY
Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)

Gene: DUSTY, DSTYK
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q6XUX3

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004712 - protein serine/threonine/tyrosine kinase activity
GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1119679

CDK13
Cyclin-dependent kinase 13

3

13

High-throughput

0.861

High

1251230

NPTN
Neuroplastin

2

3

High-throughput

0.776

High

838942

RHG25
Rho GTPase-activating protein 25

3

13

High-throughput

0.770

High

720617

GRPR
Gastrin-releasing peptide receptor

2

6

High-throughput

0.726

High

1251216

DEFI8
Differentially expressed in FDCP 8 homolog

2

6

High-throughput

0.726

High

1210880

CE170
Centrosomal protein of 170 kDa

2

5

High-throughput

0.705

High

956915

CXCR4
C-X-C chemokine receptor type 4

1

5

High-throughput

0.691

High

1251229

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

20

High-throughput

0.691

High

821735

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.679

High

946424

MTPN
Myotrophin

1

4

High-throughput

0.665

High

957617

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

3

High-throughput

0.665

High

1122515

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

11

High-throughput

0.665

High

699558

IL1R2
Interleukin-1 receptor type 2

2

5

High-throughput

0.628

High

774442

BASI
Basigin

2

4

High-throughput

0.628

High

937585

CAD13
Cadherin-13

2

7

High-throughput

0.628

High

711560

NK3R
Neuromedin-K receptor

1

3

High-throughput

0.618

High

1101541

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

9

High-throughput

0.618

High

1153400

CD226
CD226 antigen

1

10

High-throughput

0.618

High

1251219

RAB2B
Ras-related protein Rab-2B

1

5

High-throughput

0.618

High

1251225

P2RX2
P2X purinoceptor 2

2

0

High-throughput

0.602

High

900878

RAB5C
Ras-related protein Rab-5C

1

4

High-throughput

0.595

High

957955

RAB14
Ras-related protein Rab-14

1

5

High-throughput

0.595

High

142219

CCL22
C-C motif chemokine 22

2

2

High-throughput

0.574

High

1251218

FRMD1
FERM domain-containing protein 1

2

9

High-throughput

0.574

High

1251227

LAMP3
Lysosome-associated membrane glycoprotein 3

2

4

High-throughput

0.574

High

407188

CD3D
T-cell surface glycoprotein CD3 delta chain

1

2

High-throughput

0.536

High

549620

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

4

High-throughput

0.536

High

997388

TBB4B
Tubulin beta-4B chain

1

1

High-throughput

0.536

High

1101275

SLAF1
Signaling lymphocytic activation molecule

1

13

High-throughput

0.536

High

1123681

DCTN1
Dynactin subunit 1

1

4

High-throughput

0.536

High

1251217

IFT20
Intraflagellar transport protein 20 homolog

1

1

High-throughput

0.536

High

633724

PSB1
Proteasome subunit beta type-1

1

2

High-throughput

0.515

High

716476

DOPD
D-dopachrome decarboxylase

1

1

High-throughput

0.515

High

860248

RS9
Small ribosomal subunit protein uS4

1

1

High-throughput

0.515

High

887554

PSB3
Proteasome subunit beta type-3

1

3

High-throughput

0.515

High

1232084

VASN
Vasorin

1

20

High-throughput

0.514

High

190405

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.513

High

962970

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.493

High

1099706

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.493

High

1187034

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

231321

EFNA2
Ephrin-A2

1

2

High-throughput

0.489

High

570685

EDN3
Endothelin-3

1

1

High-throughput

0.489

High

642568

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

2

High-throughput

0.489

High

654648

TCEA1
Transcription elongation factor A protein 1

1

2

High-throughput

0.489

High

871168

TFPI2
Tissue factor pathway inhibitor 2

1

4

High-throughput

0.489

High

907242

ARSL
Arylsulfatase L

1

2

High-throughput

0.489

High

1022409

IDD
Integral membrane protein DGCR2/IDD

1

2

High-throughput

0.489

High

1026096

CLH1
Clathrin heavy chain 1

1

2

High-throughput

0.489

High

1200481

H1BP3
HCLS1-binding protein 3

1

1

High-throughput

0.489

High

1228628

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

1

High-throughput

0.489

High

1251226

DKKL1
Dickkopf-like protein 1

1

1

High-throughput

0.489

High

570916

MIF
Macrophage migration inhibitory factor

1

1

High-throughput

0.479

High

730697

1433S
14-3-3 protein sigma

1

6

High-throughput

0.479

High

971671

1433E
14-3-3 protein epsilon

1

4

High-throughput

0.479

High

665621

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

1

High-throughput

0.470

High

293895

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

379535

IGHM
Immunoglobulin heavy constant mu

1

3

High-throughput

0.407

High

1251220

C170L
Cep170-like protein

1

2

High-throughput

0.407

High

1251222

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

3

0

High-throughput

0.347

High

1226452

DCA15
DDB1- and CUL4-associated factor 15

2

0

High-throughput

0.318

High

192103

PA2GX
Group 10 secretory phospholipase A2

1

0

High-throughput

0.279

Low

933187

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.279

Low

956072

SPCS3
Signal peptidase complex subunit 3

1

0

High-throughput

0.279

Low

1251221

M4A10
Membrane-spanning 4-domains subfamily A member 10

1

0

High-throughput

0.279

Low

1251223

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1251224

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1251228

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

0

High-throughput

0.249

Low

469505

SYPH
Synaptophysin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025