Protein: SKA3
Spindle and kinetochore-associated protein 3

Gene: SKA3
Organism: Homo sapiens
Interactions: 147
UniProt ID: Q8IX90

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000278 - mitotic cell cycle
GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1311952

SKA1
SKA complex subunit 1

10

0

Small-scale

0.723

High

1226702

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

4

2

High-throughput

0.704

High

1311945

SKA2
Spindle and kinetochore-associated protein 2

6

0

Small-scale

0.702

High

1023827

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

4

2

High-throughput

0.701

High

1311993

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

4

2

High-throughput

0.691

High

1154536

CC85B
Coiled-coil domain-containing protein 85B

3

1

High-throughput

0.662

High

1311958

NOL4L
Nucleolar protein 4-like

3

1

High-throughput

0.662

High

317732

NOL4
Nucleolar protein 4

5

1

High-throughput

0.653

High

1311953

P5CR2
Pyrroline-5-carboxylate reductase 2

3

0

High-throughput

0.638

High

1311964

LRCC1
Leucine-rich repeat and coiled-coil domain-containing protein 1

2

0

High-throughput

0.602

High

1123707

DCTN1
Dynactin subunit 1

2

1

High-throughput

0.584

High

66630

CC85C
Coiled-coil domain-containing protein 85C

2

1

High-throughput

0.574

High

164003

NDC80
Kinetochore protein NDC80 homolog

1

1

Small-scale

0.561

High

122803

KIF2A
Kinesin-like protein KIF2A

2

0

Small-scale

0.559

High

127788

IKBE
NF-kappa-B inhibitor epsilon

1

1

High-throughput

0.536

High

1217535

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

1

High-throughput

0.536

High

1209364

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.513

High

347157

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

391337

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

549633

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

551574

K2C3
Keratin, type II cytoskeletal 3

1

0

High-throughput

0.513

High

894567

GDIB
Rab GDP dissociation inhibitor beta

1

0

High-throughput

0.513

High

930978

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.513

High

1038322

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

0

High-throughput

0.513

High

1243308

INT5
Integrator complex subunit 5

1

0

High-throughput

0.513

High

1243737

PGM2L
Glucose 1,6-bisphosphate synthase

1

0

High-throughput

0.513

High

1311939

NIN
Ninein

1

0

High-throughput

0.513

High

1311947

PALLD
Palladin

1

0

High-throughput

0.513

High

1311972

PHAX
Phosphorylated adapter RNA export protein

1

0

High-throughput

0.513

High

1311973

ECT2
Protein ECT2

1

0

High-throughput

0.513

High

1307566

ZDH17
Palmitoyltransferase ZDHHC17

1

1

High-throughput

0.494

High

1237903

PHLB3
Pleckstrin homology-like domain family B member 3

1

1

High-throughput

0.489

High

422526

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1311955

AURKB
Aurora kinase B

1

0

Small-scale

0.480

High

280710

PR40A
Pre-mRNA-processing factor 40 homolog A

1

1

Small-scale

0.479

High

487506

PARP1
Poly [ADP-ribose] polymerase 1

1

1

Small-scale

0.479

High

730753

1433S
14-3-3 protein sigma

1

2

High-throughput

0.479

High

862284

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

938235

SEC13
Protein SEC13 homolog

1

1

Small-scale

0.479

High

966588

1433G
14-3-3 protein gamma

1

2

High-throughput

0.479

High

1049534

1433F
14-3-3 protein eta

1

2

High-throughput

0.479

High

1102866

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

1

Small-scale

0.479

High

1144285

STK38
Serine/threonine-protein kinase 38

1

1

Small-scale

0.479

High

1152147

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.479

High

1311966

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

1311974

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

1

Small-scale

0.479

High

1311978

AAAS
Aladin

1

1

Small-scale

0.479

High

1311979

TBG2
Tubulin gamma-2 chain

1

1

Small-scale

0.479

High

1311983

DDX56
Probable ATP-dependent RNA helicase DDX56

1

1

Small-scale

0.479

High

1311992

MARE3
Microtubule-associated protein RP/EB family member 3

1

1

High-throughput

0.479

High

1311942

SPC24
Kinetochore protein Spc24

1

0

Small-scale

0.460

High

135271

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

0

Small-scale

0.458

High

216270

PPIH
Peptidyl-prolyl cis-trans isomerase H

1

0

Small-scale

0.458

High

245340

CE104
Centrosomal protein of 104 kDa

1

0

High-throughput

0.458

High

288460

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

0

Small-scale

0.458

High

552631

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.458

High

684302

DDX6
Probable ATP-dependent RNA helicase DDX6

1

0

Small-scale

0.458

High

831033

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

876925

KC1A
Casein kinase I isoform alpha

1

0

Small-scale

0.458

High

892894

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.458

High

911300

IMA5
Importin subunit alpha-5

1

0

Small-scale

0.458

High

920099

PLK1
Serine/threonine-protein kinase PLK1

1

0

Small-scale

0.458

High

942734

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

958147

ARP3
Actin-related protein 3

1

0

Small-scale

0.458

High

1045485

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1065733

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

0

High-throughput

0.458

High

1088903

TP53B
TP53-binding protein 1

1

0

Small-scale

0.458

High

1107896

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1109874

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

1134482

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

Small-scale

0.458

High

1177962

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1193439

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.458

High

1210900

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.458

High

1259328

TBA1A
Tubulin alpha-1A chain

1

0

Small-scale

0.458

High

1289445

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1311937

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.458

High

1311938

STAG2
Cohesin subunit SA-2

1

0

Small-scale

0.458

High

1311941

POC1A
POC1 centriolar protein homolog A

1

0

High-throughput

0.458

High

1311944

NU133
Nuclear pore complex protein Nup133

1

0

Small-scale

0.458

High

1311948

CTBL1
Beta-catenin-like protein 1

1

0

Small-scale

0.458

High

1311950

RL36L
Ribosomal protein eL42-like

1

0

Small-scale

0.458

High

1311959

SRPK1
SRSF protein kinase 1

1

0

Small-scale

0.458

High

1311962

MCMBP
Mini-chromosome maintenance complex-binding protein

1

0

Small-scale

0.458

High

1311963

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

Small-scale

0.458

High

1311971

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1311976

TRI36
E3 ubiquitin-protein ligase TRIM36

1

0

High-throughput

0.458

High

1311977

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.458

High

1311980

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

Small-scale

0.458

High

1311984

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

Small-scale

0.458

High

1311985

UBIP1
Upstream-binding protein 1

1

0

Small-scale

0.458

High

1311986

SYLC
Leucine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.458

High

1311989

NUDT5
ADP-sugar pyrophosphatase

1

0

Small-scale

0.458

High

1311991

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

Small-scale

0.458

High

589108

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

1096747

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.437

High

1122101

UBP2L
Ubiquitin-associated protein 2-like

1

1

Small-scale

0.437

High

1257069

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.437

High

1311943

LEMD2
LEM domain-containing protein 2

1

1

Small-scale

0.437

High

1311988

BAZ1B
Tyrosine-protein kinase BAZ1B

1

1

Small-scale

0.437

High

1311994

MAN1
Inner nuclear membrane protein Man1

1

1

Small-scale

0.437

High

67374

RTL8C
Retrotransposon Gag-like protein 8C

1

0

High-throughput

0.279

Low

126139

AP3B1
AP-3 complex subunit beta-1

1

0

High-throughput

0.279

Low

674235

BRD2
Bromodomain-containing protein 2

1

0

High-throughput

0.279

Low

1256781

LHPL2
LHFPL tetraspan subfamily member 2 protein

1

0

High-throughput

0.279

Low

1311331

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

0

High-throughput

0.279

Low

1311936

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.279

Low

1311946

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

1311954

HMCES
Abasic site processing protein HMCES

1

0

High-throughput

0.279

Low

1311957

MAGBA
Melanoma-associated antigen B10

1

0

High-throughput

0.279

Low

1311990

MYO5B
Unconventional myosin-Vb

1

0

High-throughput

0.279

Low

66757

RGPD3
RanBP2-like and GRIP domain-containing protein 3

1

0

Small-scale

0.249

Low

175728

SR140
U2 snRNP-associated SURP motif-containing protein

1

0

Small-scale

0.249

Low

246742

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.249

Low

255658

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

0

Small-scale

0.249

Low

330472

LC7L3
Luc7-like protein 3

1

0

Small-scale

0.249

Low

472876

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

Small-scale

0.249

Low

716697

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

1

0

Small-scale

0.249

Low

723014

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

Small-scale

0.249

Low

770018

RFC1
Replication factor C subunit 1

1

0

Small-scale

0.249

Low

838757

MTREX
Exosome RNA helicase MTR4

1

0

Small-scale

0.249

Low

889143

RBM25
RNA-binding protein 25

1

0

Small-scale

0.249

Low

1012547

RT34
Small ribosomal subunit protein mS34

1

0

Small-scale

0.249

Low

1088701

SF3A3
Splicing factor 3A subunit 3

1

0

Small-scale

0.249

Low

1168839

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

0

Small-scale

0.249

Low

1226774

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

1

0

Small-scale

0.249

Low

1276460

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1280012

CE024
UPF0461 protein C5orf24

1

0

Small-scale

0.249

Low

1310600

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

0

High-throughput

0.249

Low

1311940

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

0

Small-scale

0.249

Low

1311949

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1311951

PF21A
PHD finger protein 21A

1

0

High-throughput

0.249

Low

1311956

ZFR
Zinc finger RNA-binding protein

1

0

Small-scale

0.249

Low

1311960

CMS1
Protein CMSS1

1

0

Small-scale

0.249

Low

1311961

NOL10
Nucleolar protein 10

1

0

Small-scale

0.249

Low

1311965

DDX24
ATP-dependent RNA helicase DDX24

1

0

Small-scale

0.249

Low

1311967

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

Small-scale

0.249

Low

1311968

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1311969

HEAT1
HEAT repeat-containing protein 1

1

0

Small-scale

0.249

Low

1311970

CCD86
Coiled-coil domain-containing protein 86

1

0

Small-scale

0.249

Low

1311975

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

1311981

RBM28
RNA-binding protein 28

1

0

Small-scale

0.249

Low

1311982

SLTM
SAFB-like transcription modulator

1

0

Small-scale

0.249

Low

1311987

ABCF2
ATP-binding cassette sub-family F member 2

1

0

Small-scale

0.249

Low

1311995

TR150
Thyroid hormone receptor-associated protein 3

1

0

Small-scale

0.249

Low

1311996

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

0

Small-scale

0.249

Low

58860

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low

344241

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025