Protein: MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Man(9)-alpha-mannosidase) (Man9-mannosidase) (Mannosidase alpha class 1A member 1) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA)

Gene: MA1A1, MAN1A1
Organism: Homo sapiens
Interactions: 67
UniProt ID: P33908

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004571 - mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

755391

UPAR
Urokinase plasminogen activator surface receptor

3

0

High-throughput

0.638

High

755427

GINM1
Glycoprotein integral membrane protein 1

3

0

High-throughput

0.638

High

755429

CLDN1
Claudin domain-containing protein 1

4

1

High-throughput

0.630

High

533603

CLUS
Clusterin

2

2

High-throughput

0.628

High

755401

CC50B
Cell cycle control protein 50B

2

2

High-throughput

0.628

High

755433

UST
Uronyl 2-sulfotransferase

2

0

High-throughput

0.602

High

755389

TMEDA
Transmembrane emp24 domain-containing protein 10

2

3

High-throughput

0.601

High

480402

MMP10
Stromelysin-2

2

1

High-throughput

0.574

High

563299

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.541

High

380265

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

2

High-throughput

0.536

High

380618

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

2

High-throughput

0.536

High

437631

HEPS
Serine protease hepsin

1

7

High-throughput

0.536

High

705947

CD1B
T-cell surface glycoprotein CD1b

1

4

High-throughput

0.536

High

731820

CEAM8
Cell adhesion molecule CEACAM8

1

3

High-throughput

0.536

High

755396

TMED2
Transmembrane emp24 domain-containing protein 2

1

3

High-throughput

0.536

High

755400

P3H1
Prolyl 3-hydroxylase 1

1

1

High-throughput

0.536

High

755410

CHSS3
Chondroitin sulfate synthase 3

1

1

High-throughput

0.536

High

755412

NRSN1
Neurensin-1

1

1

High-throughput

0.536

High

755414

F241A
Uncharacterized protein FAM241A

1

2

High-throughput

0.536

High

755419

TMM59
Transmembrane protein 59

1

1

High-throughput

0.536

High

755420

TMPSD
Transmembrane protease serine 13

1

7

High-throughput

0.536

High

755422

CHST8
Carbohydrate sulfotransferase 8

1

3

High-throughput

0.536

High

755432

CCPG1
Cell cycle progression protein 1

1

2

High-throughput

0.536

High

137043

PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

1

0

High-throughput

0.513

High

283662

GPC4
Glypican-4

1

0

High-throughput

0.513

High

593288

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.513

High

755392

MGAT2
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.513

High

755394

GAS6
Growth arrest-specific protein 6

1

0

High-throughput

0.513

High

755397

OCLN
Occludin

1

0

High-throughput

0.513

High

755413

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

755415

NLGN2
Neuroligin-2

1

0

High-throughput

0.513

High

755421

CNTP3
Contactin-associated protein-like 3

1

0

High-throughput

0.513

High

755425

GORS2
Golgi reassembly-stacking protein 2

1

0

High-throughput

0.513

High

755428

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

1

0

High-throughput

0.513

High

416596

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

2

High-throughput

0.489

High

472387

FGF4
Fibroblast growth factor 4

1

1

High-throughput

0.489

High

710089

EPHA2
Ephrin type-A receptor 2

1

2

High-throughput

0.489

High

755388

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

1

High-throughput

0.489

High

755393

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

1

High-throughput

0.489

High

755399

CL12B
C-type lectin domain family 12 member B

1

4

High-throughput

0.489

High

755403

LRC24
Leucine-rich repeat-containing protein 24

1

1

High-throughput

0.489

High

755406

IL31
Interleukin-31

1

1

High-throughput

0.489

High

755418

T106A
Transmembrane protein 106A

1

1

High-throughput

0.489

High

755423

SG196
Protein O-mannose kinase

1

1

High-throughput

0.489

High

755426

CBLN4
Cerebellin-4

1

3

High-throughput

0.489

High

755434

ST14
Suppressor of tumorigenicity 14 protein

1

7

High-throughput

0.489

High

217887

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

255994

S19A2
Thiamine transporter 1

1

1

High-throughput

0.445

High

469708

MMP3
Stromelysin-1

1

1

High-throughput

0.445

High

755395

S39AE
Metal cation symporter ZIP14

1

10

High-throughput

0.445

High

755407

S39A4
Zinc transporter ZIP4

1

10

High-throughput

0.445

High

755416

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

3

High-throughput

0.445

High

755390

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

755408

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

755409

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

755404

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

755405

NTCP5
Sodium/bile acid cotransporter 5

1

0

High-throughput

0.426

High

2093

TVA20
T cell receptor alpha variable 20

1

1

High-throughput

0.407

High

755398

MICB
MHC class I polypeptide-related sequence B

1

1

High-throughput

0.407

High

755402

S39AC
Zinc transporter ZIP12

1

10

High-throughput

0.407

High

755424

CDCP1
CUB domain-containing protein 1

2

0

High-throughput

0.328

High

378592

EPO
Erythropoietin

1

0

High-throughput

0.279

Low

755411

IFNE
Interferon epsilon

1

0

High-throughput

0.279

Low

755417

IGDC4
Immunoglobulin superfamily DCC subclass member 4

1

0

High-throughput

0.279

Low

755431

DKKL1
Dickkopf-like protein 1

1

0

High-throughput

0.279

Low

239412

3BP5
SH3 domain-binding protein 5

1

0

High-throughput

0.238

Low

755430

S53A1
Solute carrier family 53 member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025