Protein: TRFM
Melanotransferrin (Melanoma-associated antigen p97) (CD antigen CD228)

Gene: TRFM, MELTF
Organism: Homo sapiens
Interactions: 77
UniProt ID: P08582

Gene Ontology (top 5):
GO:0005506 - iron ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005769 - early endosome
GO:0005788 - endoplasmic reticulum lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

472206

SIRPD
Signal-regulatory protein delta

1

1

High-throughput

0.691

High

472187

NT2NA
Notch homolog 2 N-terminal-like protein A

3

2

High-throughput

0.667

High

472161

CFTR
Cystic fibrosis transmembrane conductance regulator

2

2

High-throughput

0.608

High

472156

PAEP
Glycodelin

2

1

High-throughput

0.601

High

70088

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.580

High

472173

MESD
LRP chaperone MESD

2

0

High-throughput

0.580

High

472169

KR108
Keratin-associated protein 10-8

2

1

High-throughput

0.553

High

472172

KRA11
Keratin-associated protein 1-1

2

1

High-throughput

0.553

High

399426

TRGV3
T cell receptor gamma variable 3

1

0

High-throughput

0.546

High

472160

FGFR1
Fibroblast growth factor receptor 1

1

3

High-throughput

0.536

High

472163

PRG2
Bone marrow proteoglycan

1

2

High-throughput

0.536

High

472168

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.536

High

472181

TBB8
Tubulin beta-8 chain

1

2

High-throughput

0.536

High

472186

LYPD4
Ly6/PLAUR domain-containing protein 4

1

1

High-throughput

0.536

High

472199

ESPB1
Epididymal sperm-binding protein 1

1

1

High-throughput

0.536

High

472207

KLK15
Kallikrein-15

1

3

High-throughput

0.536

High

472213

LOXL2
Lysyl oxidase homolog 2

1

2

High-throughput

0.536

High

472214

LIPG
Endothelial lipase

1

3

High-throughput

0.536

High

472157

NT2NC
Notch homolog 2 N-terminal-like protein C

1

2

High-throughput

0.515

High

65930

LIRA5
Leukocyte immunoglobulin-like receptor subfamily A member 5

1

0

High-throughput

0.513

High

327026

NXPH3
Neurexophilin-3

1

0

High-throughput

0.513

High

342495

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.513

High

472158

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

472162

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.513

High

472164

EDN3
Endothelin-3

1

0

High-throughput

0.513

High

472165

PDIA3
Protein disulfide-isomerase A3

1

0

Small-scale

0.513

High

472170

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.513

High

472179

H2A2C
Histone H2A type 2-C

1

0

High-throughput

0.513

High

472188

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.513

High

472197

MADD
MAP kinase-activating death domain protein

1

0

High-throughput

0.513

High

472198

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

472208

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

472209

CBLN4
Cerebellin-4

1

0

High-throughput

0.513

High

472211

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

0

High-throughput

0.513

High

472216

ICOS
Inducible T-cell costimulator

1

0

High-throughput

0.513

High

472176

OZF
Zinc finger protein OZF

1

1

High-throughput

0.489

High

472183

WDR25
WD repeat-containing protein 25

1

1

High-throughput

0.489

High

472201

SFXN2
Sideroflexin-2

1

2

High-throughput

0.489

High

472202

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

1

High-throughput

0.489

High

472204

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

1

High-throughput

0.489

High

472215

ORNT1
Mitochondrial ornithine transporter 1

1

1

High-throughput

0.489

High

410539

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

4

High-throughput

0.479

High

472171

FAK1
Focal adhesion kinase 1

1

2

Small-scale

0.479

High

472203

ACE2
Angiotensin-converting enzyme 2

1

1

Small-scale

0.479

High

217738

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

472166

BASI
Basigin

1

0

High-throughput

0.458

High

472190

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.458

High

472159

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

2

High-throughput

0.445

High

472167

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

High-throughput

0.445

High

472194

MOT10
Monocarboxylate transporter 10

1

2

High-throughput

0.445

High

472212

FLVC2
Choline/ethanolamine transporter FLVCR2

1

1

High-throughput

0.445

High

105160

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

337064

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.426

High

472177

NF2L2
Nuclear factor erythroid 2-related factor 2

1

0

High-throughput

0.426

High

472180

SC5AC
Sodium-coupled monocarboxylate transporter 2

1

0

High-throughput

0.426

High

472196

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.426

High

472210

RHCG
Ammonium transporter Rh type C

1

0

High-throughput

0.426

High

170631

CLGN
Calmegin

1

2

High-throughput

0.407

High

255537

HPGDS
Hematopoietic prostaglandin D synthase

2

0

High-throughput

0.327

High

472178

TAZ
Tafazzin

2

0

High-throughput

0.318

High

158975

ZN195
Zinc finger protein 195

1

0

High-throughput

0.279

Low

281166

CDC45
Cell division control protein 45 homolog

1

0

High-throughput

0.279

Low

326650

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.279

Low

472174

DPOD3
DNA polymerase delta subunit 3

1

0

High-throughput

0.279

Low

472182

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

0

High-throughput

0.279

Low

472184

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

0

High-throughput

0.279

Low

472185

INT5
Integrator complex subunit 5

1

0

High-throughput

0.279

Low

472189

TRM2A
tRNA

1

0

High-throughput

0.279

Low

472192

SEN2
tRNA-splicing endonuclease subunit Sen2

1

0

High-throughput

0.279

Low

472193

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.279

Low

472195

SEN15
tRNA-splicing endonuclease subunit Sen15

1

0

High-throughput

0.279

Low

472205

ZY11B
Protein zyg-11 homolog B

1

0

High-throughput

0.279

Low

464

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.251

Low

247612

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

472175

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

472191

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

472200

MFSD3
Major facilitator superfamily domain-containing protein 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025