Protein: JOS1
Josephin-1 (EC 3.4.19.12) (Josephin domain-containing protein 1)

Gene: JOS1, JOSD1
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q15040

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475787

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

4

5

Small-scale

0.899

High

889480

KR108
Keratin-associated protein 10-8

3

8

High-throughput

0.675

High

1065225

K1C40
Keratin, type I cytoskeletal 40

3

3

High-throughput

0.675

High

1065238

KRA92
Keratin-associated protein 9-2

3

9

High-throughput

0.675

High

124866

EIF3F
Eukaryotic translation initiation factor 3 subunit F

3

2

High-throughput

0.667

High

1065223

K1H1
Keratin, type I cuticular Ha1

2

3

High-throughput

0.633

High

536837

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.613

High

280583

KRT34
Keratin, type I cuticular Ha4

2

3

High-throughput

0.606

High

991565

KRA11
Keratin-associated protein 1-1

2

8

High-throughput

0.606

High

1065226

ATL4
ADAMTS-like protein 4

2

1

High-throughput

0.606

High

1065228

K1C27
Keratin, type I cytoskeletal 27

2

2

High-throughput

0.606

High

1065229

KRA13
Keratin-associated protein 1-3

2

9

High-throughput

0.606

High

1065237

KRA93
Keratin-associated protein 9-3

2

9

High-throughput

0.606

High

992166

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

2

1

Small-scale

0.584

High

213950

KRT86
Keratin, type II cuticular Hb6

2

0

High-throughput

0.580

High

611245

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

0

High-throughput

0.580

High

888535

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.580

High

1065227

NT2NA
Notch homolog 2 N-terminal-like protein A

2

1

High-throughput

0.578

High

642055

KRA59
Keratin-associated protein 5-9

1

8

High-throughput

0.573

High

734633

TRI23
E3 ubiquitin-protein ligase TRIM23

1

1

High-throughput

0.573

High

1023663

TRAF1
TNF receptor-associated factor 1

1

2

High-throughput

0.573

High

957268

FBLN2
Fibulin-2

2

1

High-throughput

0.553

High

1065224

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

3

High-throughput

0.553

High

486027

RAP2A
Ras-related protein Rap-2a

1

1

High-throughput

0.536

High

1065241

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

11

High-throughput

0.523

High

889213

KR104
Keratin-associated protein 10-4

1

6

High-throughput

0.515

High

1065239

KRA24
Keratin-associated protein 2-4

1

9

High-throughput

0.515

High

1065234

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

3

High-throughput

0.501

High

1065242

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

2

High-throughput

0.501

High

1065243

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

Small-scale

0.501

High

1065244

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

High-throughput

0.501

High

473282

KRA23
Keratin-associated protein 2-3

1

9

High-throughput

0.481

High

888872

KR103
Keratin-associated protein 10-3

1

9

High-throughput

0.481

High

160574

AURKA
Aurora kinase A

1

3

Small-scale

0.479

High

181863

SOCS1
Suppressor of cytokine signaling 1

1

1

Small-scale

0.479

High

238411

JAK2
Tyrosine-protein kinase JAK2

1

1

Small-scale

0.479

High

326647

SNAI1
Zinc finger protein SNAI1

1

1

Small-scale

0.479

High

717093

CTNB1
Catenin beta-1

1

2

Small-scale

0.479

High

1036589

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

1054128

BECN1
Beclin-1

1

1

Small-scale

0.479

High

1065230

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

2

Small-scale

0.479

High

484607

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

262274

ULK1
Serine/threonine-protein kinase ULK1

1

0

Small-scale

0.458

High

1065231

PJA1
E3 ubiquitin-protein ligase Praja-1

1

4

High-throughput

0.457

High

1065233

TRI63
E3 ubiquitin-protein ligase TRIM63

1

10

High-throughput

0.457

High

1065240

TRI54
Tripartite motif-containing protein 54

1

10

High-throughput

0.457

High

67081

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

1065235

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

1065236

CAR10
Caspase recruitment domain-containing protein 10

2

0

High-throughput

0.316

High

648505

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

224618

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

0

High-throughput

0.269

Low

519

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.251

Low

1065232

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.251

Low


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Last updated: 15 Jul 2024