Protein: ULBP3
UL16-binding protein 3 (ALCAN-gamma) (NKG2D ligand 3) (N2DL-3) (NKG2DL3) (Retinoic acid early transcript 1N)

Gene: ULBP3
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q9BZM4

Gene Ontology (top 5):
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002476 - antigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO:0002486 - antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO:0005615 - extracellular space
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

627566

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

3

19

High-throughput

0.861

High

705989

CD1B
T-cell surface glycoprotein CD1b

3

17

High-throughput

0.861

High

1186229

CEA21
Cell adhesion molecule CEACAM21

3

8

High-throughput

0.861

High

688710

NKG2D
NKG2-D type II integral membrane protein

3

20

Small-scale

0.840

High

939528

FCGRN
IgG receptor FcRn large subunit p51

2

16

High-throughput

0.811

High

1350317

RAE1E
Retinoic acid early transcript 1E

2

17

High-throughput

0.811

High

1420091

ULBP1
UL16-binding protein 1

2

17

High-throughput

0.811

High

553372

FCGR1
High affinity immunoglobulin gamma Fc receptor I

1

11

High-throughput

0.691

High

580832

PVR
Poliovirus receptor

1

4

High-throughput

0.691

High

619921

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.691

High

1249843

BTNL9
Butyrophilin-like protein 9

1

7

High-throughput

0.691

High

1420096

SCN3B
Sodium channel regulatory subunit beta-3

1

2

High-throughput

0.691

High

749387

TNFL8
Tumor necrosis factor ligand superfamily member 8

3

3

High-throughput

0.662

High

1197879

S39AC
Zinc transporter ZIP12

3

20

High-throughput

0.662

High

1251798

S39A5
Zinc transporter ZIP5

3

20

High-throughput

0.662

High

596529

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.656

High

1128949

I13R2
Interleukin-13 receptor subunit alpha-2

2

11

High-throughput

0.628

High

1187219

CC50B
Cell cycle control protein 50B

2

7

High-throughput

0.628

High

1248394

I27RA
Interleukin-27 receptor subunit alpha

2

10

High-throughput

0.628

High

1402441

CCNL2
Cyclin-L2

3

1

High-throughput

0.609

High

1244083

CXB7
Gap junction beta-7 protein

2

6

High-throughput

0.574

High

1420095

GINM1
Glycoprotein integral membrane protein 1

2

2

High-throughput

0.558

High

221474

OX2R
Orexin receptor type 2

1

1

High-throughput

0.536

High

252566

TSN1
Tetraspanin-1

1

3

High-throughput

0.536

High

277402

TP4A3
Protein tyrosine phosphatase type IVA 3

1

2

High-throughput

0.536

High

328734

VAMP5
Vesicle-associated membrane protein 5

1

1

High-throughput

0.536

High

437784

HEPS
Serine protease hepsin

1

14

High-throughput

0.536

High

593490

PGFRA
Platelet-derived growth factor receptor alpha

1

14

High-throughput

0.536

High

689963

IL3RA
Interleukin-3 receptor subunit alpha

1

7

High-throughput

0.536

High

761289

RYK
Tyrosine-protein kinase RYK

1

20

High-throughput

0.536

High

880198

PTH2R
Parathyroid hormone 2 receptor

1

3

High-throughput

0.536

High

1245918

BRID5
BRICHOS domain-containing protein 5

1

5

High-throughput

0.536

High

1420094

DUS22
Dual specificity protein phosphatase 22

1

1

High-throughput

0.536

High

1420098

SLAF8
SLAM family member 8

1

16

High-throughput

0.536

High

1420101

PCDA9
Protocadherin alpha-9

1

8

High-throughput

0.536

High

1420102

ST14
Suppressor of tumorigenicity 14 protein

1

14

High-throughput

0.536

High

378650

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.513

High

1248468

PARM1
Prostate androgen-regulated mucin-like protein 1

1

0

High-throughput

0.513

High

1337787

TRPV3
Transient receptor potential cation channel subfamily V member 3

1

0

High-throughput

0.513

High

1350789

MO2R1
Cell surface glycoprotein CD200 receptor 1

1

0

High-throughput

0.513

High

1420097

GPC5D
G-protein coupled receptor family C group 5 member D

1

0

High-throughput

0.513

High

1206276

NHLC3
NHL repeat-containing protein 3

1

1

High-throughput

0.489

High

1315328

ZDH23
Palmitoyltransferase ZDHHC23

1

2

High-throughput

0.489

High

1369483

TANK
TRAF family member-associated NF-kappa-B activator

1

1

High-throughput

0.489

High

1391286

CERS2
Ceramide synthase 2

1

1

High-throughput

0.489

High

1418790

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

1

High-throughput

0.489

High

1420092

SHRPN
Sharpin

1

1

High-throughput

0.489

High

1418430

ACE2
Angiotensin-converting enzyme 2

1

3

Small-scale

0.479

High

370776

FOS
Protein c-Fos

1

2

High-throughput

0.470

High

728821

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

1

High-throughput

0.470

High

222324

PSCA
Prostate stem cell antigen

1

2

High-throughput

0.445

High

1353716

MOT10
Monocarboxylate transporter 10

1

3

High-throughput

0.445

High

1420099

RHCG
Ammonium transporter Rh type C

1

1

High-throughput

0.445

High

1420100

S39AA
Zinc transporter ZIP10

1

20

High-throughput

0.445

High

872723

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.437

High

354034

CX001
Putative transmembrane protein CXorf1

1

0

High-throughput

0.279

Low

1315990

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

1420093

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

959246

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025