Protein: MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase)

Gene: MALT1
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q9UDY8

Gene Ontology (top 5):
GO:0001650 - fibrillar center
GO:0001923 - B-1 B cell differentiation
GO:0002020 - protease binding
GO:0002096 - polkadots
GO:0002726 - positive regulation of T cell cytokine production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1458961

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

7

16

Small-scale

0.971

High

1395446

FEM1C
Protein fem-1 homolog C

2

8

High-throughput

0.783

High

1412773

FEM1A
Protein fem-1 homolog A

2

10

High-throughput

0.783

High

353908

BCL10
B-cell lymphoma/leukemia 10

33

1

Small-scale

0.770

High

1458965

TRAF6
TNF receptor-associated factor 6

7

9

Small-scale

0.752

High

1417019

CAR11
Caspase recruitment domain-containing protein 11

6

8

Small-scale

0.724

High

1458966

NEMO
NF-kappa-B essential modulator

5

12

Small-scale

0.712

High

445282

S10A6
Protein S100-A6

1

6

High-throughput

0.691

High

877032

KC1A
Casein kinase I isoform alpha

3

5

Small-scale

0.656

High

1402078

TRIB1
Tribbles homolog 1

2

4

High-throughput

0.628

High

683529

IKBA
NF-kappa-B inhibitor alpha

1

11

Small-scale

0.618

High

1255949

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.618

High

1132459

CASP8
Caspase-8

1

0

Small-scale

0.613

High

1108248

SQSTM
Sequestosome-1

2

5

Small-scale

0.612

High

508772

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

4

Small-scale

0.611

High

639322

TNAP3
Tumor necrosis factor alpha-induced protein 3

2

4

Small-scale

0.611

High

1417013

CAR14
Caspase recruitment domain-containing protein 14

2

8

Small-scale

0.611

High

1030045

RELB
Transcription factor RelB

2

2

Small-scale

0.602

High

214054

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

10

Small-scale

0.601

High

1452630

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

2

6

Small-scale

0.601

High

288532

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

4

Small-scale

0.595

High

1090958

TRAF2
TNF receptor-associated factor 2

2

8

Small-scale

0.595

High

1418826

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

2

1

Small-scale

0.595

High

1389410

RNF31
E3 ubiquitin-protein ligase RNF31

2

4

Small-scale

0.584

High

1429996

SHRPN
Sharpin

2

1

Small-scale

0.584

High

927163

ATX3
Ataxin-3

2

0

Small-scale

0.575

High

1107302

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

Small-scale

0.575

High

1094438

CSN1
COP9 signalosome complex subunit 1

1

2

Small-scale

0.554

High

1212624

HECD3
E3 ubiquitin-protein ligase HECTD3

1

14

Small-scale

0.552

High

957857

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

4

Small-scale

0.550

High

1154302

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

5

Small-scale

0.550

High

167988

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

9

Small-scale

0.536

High

1129283

LAGE3
EKC/KEOPS complex subunit LAGE3

1

1

High-throughput

0.536

High

1370435

CSN5
COP9 signalosome complex subunit 5

1

2

Small-scale

0.536

High

952477

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

2

High-throughput

0.515

High

1048297

KPCT
Protein kinase C theta type

1

9

Small-scale

0.515

High

1051980

KPCD
Protein kinase C delta type

1

6

Small-scale

0.515

High

167412

KLF11
Krueppel-like factor 11

1

4

High-throughput

0.515

High

246174

KIF1B
Kinesin-like protein KIF1B

1

4

High-throughput

0.515

High

415914

HSPB1
Heat shock protein beta-1

1

5

High-throughput

0.515

High

856965

BAG6
Large proline-rich protein BAG6

1

8

High-throughput

0.515

High

896915

DYN2
Dynamin-2

1

8

High-throughput

0.515

High

1279785

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

7

High-throughput

0.515

High

302091

SEGN
Secretagogin

1

0

High-throughput

0.513

High

963383

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.513

High

1413869

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.513

High

247010

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.508

High

1293430

CARM1
Histone-arginine methyltransferase CARM1

1

1

High-throughput

0.508

High

1396939

ANM6
Protein arginine N-methyltransferase 6

1

1

High-throughput

0.508

High

165780

PAHX
Phytanoyl-CoA dioxygenase, peroxisomal

1

0

High-throughput

0.493

High

301745

WFS1
Wolframin

1

0

High-throughput

0.493

High

954635

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

571532

GLU2B
Glucosidase 2 subunit beta

1

3

High-throughput

0.489

High

1206692

LRC73
Leucine-rich repeat-containing protein 73

1

2

High-throughput

0.489

High

216553

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.486

High

107343

F8VWT9
HECT domain E3 ubiquitin protein ligase 4

1

11

Small-scale

0.479

High

173502

XPO1
Exportin-1

1

4

High-throughput

0.479

High

342348

BRD1
Bromodomain-containing protein 1

1

5

High-throughput

0.479

High

447541

NPM
Nucleophosmin

1

2

High-throughput

0.479

High

669151

ARBK1
Beta-adrenergic receptor kinase 1

1

15

Small-scale

0.479

High

831587

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

853862

MK09
Mitogen-activated protein kinase 9

1

9

Small-scale

0.479

High

887477

CEBPD
CCAAT/enhancer-binding protein delta

1

4

Small-scale

0.479

High

971238

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

1022201

DAB2
Disabled homolog 2

1

9

Small-scale

0.479

High

1035969

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

1094998

TRAF3
TNF receptor-associated factor 3

1

11

Small-scale

0.479

High

1106736

SMAD4
Mothers against decapentaplegic homolog 4

1

1

High-throughput

0.479

High

1110419

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

4

Small-scale

0.479

High

1114554

CUL3
Cullin-3

1

11

High-throughput

0.479

High

1371562

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

2

Small-scale

0.479

High

1400093

QKI
KH domain-containing RNA-binding protein QKI

1

1

Small-scale

0.479

High

1434142

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.479

High

1446992

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

Small-scale

0.479

High

1458963

CHIP
E3 ubiquitin-protein ligase CHIP

1

6

Small-scale

0.479

High

1458964

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

1

High-throughput

0.479

High

109526

G5E9A7
DM1 locus, WD repeat containing

1

5

High-throughput

0.470

High

705592

GRN
Progranulin

1

1

High-throughput

0.470

High

822896

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

1384831

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

1447784

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

Small-scale

0.458

High

1431518

CARD9
Caspase recruitment domain-containing protein 9

1

9

Small-scale

0.445

High

1458962

ASC
Apoptosis-associated speck-like protein containing a CARD

1

2

Small-scale

0.445

High

289373

CTAG2
Cancer/testis antigen 2

1

0

High-throughput

0.279

Low

1415750

FND11
Fibronectin type III domain-containing protein 11

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025