Protein: MPU1
Mannose-P-dolichol utilization defect 1 protein (Suppressor of Lec15 and Lec35 glycosylation mutation homolog) (SL15)

Gene: MPU1, MPDU1
Organism: Homo sapiens
Interactions: 60
UniProt ID: O75352

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0006457 - protein folding
GO:0006488 - dolichol-linked oligosaccharide biosynthetic process
GO:0009312 - oligosaccharide biosynthetic process
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

276979

MANBL
Protein MANBAL

2

0

High-throughput

0.580

High

226297

SNG1
Synaptogyrin-1

1

1

High-throughput

0.536

High

276942

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

276976

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

1

High-throughput

0.536

High

276983

CLC2D
C-type lectin domain family 2 member D

1

1

High-throughput

0.536

High

124995

KCNK1
Potassium channel subfamily K member 1

1

0

High-throughput

0.513

High

276941

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.513

High

276957

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

276958

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.513

High

276968

PDPN
Podoplanin

1

0

High-throughput

0.513

High

276971

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

276934

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.493

High

276960

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.493

High

276961

AAAT
Neutral amino acid transporter B(0)

1

0

High-throughput

0.493

High

165872

FFAR1
Free fatty acid receptor 1

1

1

High-throughput

0.489

High

276935

S1PR4
Sphingosine 1-phosphate receptor 4

1

1

High-throughput

0.489

High

276945

EDNRA
Endothelin-1 receptor

1

1

High-throughput

0.489

High

276980

GPR84
G-protein coupled receptor 84

1

1

High-throughput

0.489

High

276937

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

276981

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

156761

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

178119

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

276967

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

0

High-throughput

0.458

High

276969

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.458

High

276973

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

188744

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.437

High

276936

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.437

High

276966

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

276982

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

Small-scale

0.426

High

276944

TSN8
Tetraspanin-8

1

0

High-throughput

0.279

Low

276947

5HT1B
5-hydroxytryptamine receptor 1B

1

0

High-throughput

0.279

Low

276948

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

276950

APJ
Apelin receptor

1

0

High-throughput

0.279

Low

276951

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

0

High-throughput

0.279

Low

276964

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

276970

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

276972

RELL2
RELT-like protein 2

1

0

High-throughput

0.279

Low

276955

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.269

Low

276959

MO4L2
Mortality factor 4-like protein 2

1

0

High-throughput

0.269

Low

276978

QRIC2
Glutamine-rich protein 2

1

0

High-throughput

0.269

Low

177981

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

0

High-throughput

0.251

Low

276938

SHBG
Sex hormone-binding globulin

1

0

Small-scale

0.251

Low

104950

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

125103

LEG9
Galectin-9

1

0

High-throughput

0.249

Low

227275

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

276939

P53
Cellular tumor antigen p53

1

0

High-throughput

0.249

Low

276940

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.249

Low

276943

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

276946

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

276949

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

276952

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

276953

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.249

Low

276954

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.249

Low

276956

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

276962

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

276963

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.249

Low

276965

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

276974

CLC4D
C-type lectin domain family 4 member D

1

0

High-throughput

0.249

Low

276975

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.249

Low

276977

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025