Protein: CAH2
Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II) (Cyanamide hydratase CA2) (EC 4.2.1.69)

Gene: CAH2, CA2
Organism: Homo sapiens
Interactions: 71
UniProt ID: P00918

Gene Ontology (top 5):
GO:0002009 - morphogenesis of an epithelium
GO:0004064 - arylesterase activity
GO:0004089 - carbonate dehydratase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

367559

B3AT
Band 3 anion transport protein

4

5

Small-scale

0.688

High

367558

CAH2
Carbonic anhydrase 2

1

6

High-throughput

0.618

High

367589

CAH9
Carbonic anhydrase 9

1

6

Small-scale

0.618

High

367567

SL9A1
Sodium/hydrogen exchanger 1

2

0

Small-scale

0.607

High

240434

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

367593

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

2

High-throughput

0.571

High

367618

RHG26
Rho GTPase-activating protein 26

2

0

High-throughput

0.547

High

367561

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.536

High

367584

CUL1
Cullin-1

1

2

High-throughput

0.536

High

367585

CUL4A
Cullin-4A

1

2

High-throughput

0.536

High

367598

NEK8
Serine/threonine-protein kinase Nek8

1

1

High-throughput

0.536

High

367612

KDM4C
Lysine-specific demethylase 4C

1

0

High-throughput

0.513

High

367614

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

0

High-throughput

0.513

High

367590

S4A8
Electroneutral sodium bicarbonate exchanger 1

1

5

Small-scale

0.501

High

367564

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.493

High

323642

AP2A2
AP-2 complex subunit alpha-2

1

1

High-throughput

0.479

High

344591

AP2A1
AP-2 complex subunit alpha-1

1

1

High-throughput

0.479

High

367563

EPB41
Protein 4.1

1

2

High-throughput

0.479

High

367571

FUS
RNA-binding protein FUS

1

1

High-throughput

0.479

High

367575

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

367580

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

367581

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

367583

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

367587

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

367604

ARMC5
Armadillo repeat-containing protein 5

1

5

High-throughput

0.479

High

367608

RNF5
E3 ubiquitin-protein ligase RNF5

1

1

High-throughput

0.479

High

367611

RNF26
E3 ubiquitin-protein ligase RNF26

1

1

High-throughput

0.479

High

367616

TBK1
Serine/threonine-protein kinase TBK1

1

2

High-throughput

0.479

High

367568

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

367572

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

367573

RL21
Large ribosomal subunit protein eL21

1

0

High-throughput

0.458

High

367574

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

0

High-throughput

0.458

High

367576

KC1E
Casein kinase I isoform epsilon

1

0

High-throughput

0.458

High

367578

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

367579

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.458

High

367582

KMT2A
Histone-lysine N-methyltransferase 2A

1

0

High-throughput

0.458

High

367586

SRC8
Src substrate cortactin

1

0

High-throughput

0.458

High

367594

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

0

High-throughput

0.458

High

367595

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

367597

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

367600

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.458

High

367606

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

367607

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

367610

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.458

High

367617

VAV3
Guanine nucleotide exchange factor VAV3

1

0

High-throughput

0.458

High

367619

NINL
Ninein-like protein

1

0

High-throughput

0.458

High

367620

PRC2C
Protein PRRC2C

1

0

High-throughput

0.458

High

367577

NAC3
Sodium/calcium exchanger 3

1

1

High-throughput

0.445

High

367591

SV2C
Synaptic vesicle glycoprotein 2C

1

1

High-throughput

0.445

High

367609

PKP2
Plakophilin-2

1

4

High-throughput

0.445

High

367613

ANKZ1
tRNA endonuclease ANKZF1

1

0

High-throughput

0.438

High

367615

DISP3
Protein dispatched homolog 3

1

0

High-throughput

0.438

High

105059

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

367570

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

367602

DEP1B
DEP domain-containing protein 1B

1

2

High-throughput

0.437

High

261039

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

295442

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

0

High-throughput

0.426

High

367562

CH60
60 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.426

High

367569

SC5A2
Sodium/glucose cotransporter 2

1

0

High-throughput

0.426

High

367592

S22A6
Solute carrier family 22 member 6

1

0

High-throughput

0.426

High

367599

S41A1
Solute carrier family 41 member 1

1

0

High-throughput

0.426

High

367601

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

0

High-throughput

0.426

High

367603

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.426

High

367605

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.426

High

367596

NEK10
Serine/threonine-protein kinase Nek10

1

1

High-throughput

0.407

High

367588

NONO
Non-POU domain-containing octamer-binding protein

1

0

Small-scale

0.261

Low

352818

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

367565

KCRU
Creatine kinase U-type, mitochondrial

1

0

High-throughput

0.249

Low

367566

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

367560

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025