Protein: ADDB
Beta-adducin (Erythrocyte adducin subunit beta)

Gene: ADDB, ADD2
Organism: Homo sapiens
Interactions: 83
UniProt ID: P35612

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005516 - calmodulin binding
GO:0005829 - cytosol
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

774027

ADDA
Alpha-adducin

3

5

High-throughput

0.861

High

774176

ADDG
Gamma-adducin

2

4

High-throughput

0.811

High

774172

DEFI6
Differentially expressed in FDCP 6 homolog

3

2

High-throughput

0.667

High

375241

RASK
GTPase KRas

3

20

High-throughput

0.640

High

270779

ROCK2
Rho-associated protein kinase 2

2

5

High-throughput

0.628

High

774145

ROCK1
Rho-associated protein kinase 1

2

5

High-throughput

0.628

High

774169

DUS23
Dual specificity protein phosphatase 23

2

3

High-throughput

0.628

High

774138

ACTB
Actin, cytoplasmic 1

2

7

High-throughput

0.611

High

774156

DPPA4
Developmental pluripotency-associated protein 4

3

3

High-throughput

0.609

High

774160

ANR29
Ankyrin repeat domain-containing protein 29

3

8

High-throughput

0.609

High

774179

SPB13
Serpin B13

2

0

High-throughput

0.602

High

373806

RASN
GTPase NRas

2

20

High-throughput

0.584

High

540333

LAMP1
Lysosome-associated membrane glycoprotein 1

2

4

High-throughput

0.584

High

774167

NUD12
NAD-capped RNA hydrolase NUDT12

2

7

High-throughput

0.574

High

440415

FYN
Tyrosine-protein kinase Fyn

1

6

Small-scale

0.561

High

470262

NEP
Neprilysin

1

1

High-throughput

0.536

High

529220

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.536

High

593731

PECA1
Platelet endothelial cell adhesion molecule

1

7

High-throughput

0.536

High

774135

DAPK1
Death-associated protein kinase 1

1

8

High-throughput

0.536

High

774147

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

5

High-throughput

0.536

High

774159

PNKD
Probable thioesterase PNKD

1

1

High-throughput

0.536

High

774168

FEM1A
Protein fem-1 homolog A

1

7

High-throughput

0.536

High

774146

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

0

High-throughput

0.513

High

774151

ASTRB
Protein Aster-B

1

0

High-throughput

0.513

High

774158

ABRA
Actin-binding Rho-activating protein

1

0

High-throughput

0.513

High

774165

ZN641
Zinc finger protein 641

1

0

High-throughput

0.513

High

421607

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

774136

CRIS3
Cysteine-rich secretory protein 3

1

1

High-throughput

0.489

High

774148

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.489

High

126485

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

189439

STX7
Syntaxin-7

1

2

High-throughput

0.479

High

240913

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

299087

FLOT1
Flotillin-1

1

4

High-throughput

0.479

High

332891

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.479

High

362880

EGFR
Epidermal growth factor receptor

1

8

High-throughput

0.479

High

374435

RASH
GTPase HRas

1

14

High-throughput

0.479

High

463379

LYN
Tyrosine-protein kinase Lyn

1

6

High-throughput

0.479

High

541372

FGFR1
Fibroblast growth factor receptor 1

1

6

High-throughput

0.479

High

601191

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

642667

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.479

High

658996

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

1

High-throughput

0.479

High

659074

PTPRZ
Receptor-type tyrosine-protein phosphatase zeta

1

2

High-throughput

0.479

High

694768

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

710098

EPHA2
Ephrin type-A receptor 2

1

10

High-throughput

0.479

High

710787

EPHB2
Ephrin type-B receptor 2

1

6

High-throughput

0.479

High

715458

MARCS
Myristoylated alanine-rich C-kinase substrate

1

7

High-throughput

0.479

High

774134

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

774139

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

774140

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

774141

CXAR
Coxsackievirus and adenovirus receptor

1

5

High-throughput

0.479

High

774142

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

774143

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

774144

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

774149

RAB35
Ras-related protein Rab-35

1

5

High-throughput

0.479

High

774150

OCLN
Occludin

1

4

High-throughput

0.479

High

774154

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.479

High

774155

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

774161

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

774170

DNJC5
DnaJ homolog subfamily C member 5

1

7

High-throughput

0.479

High

774171

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

774173

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

774175

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.479

High

623152

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.458

High

774166

VP13A
Intermembrane lipid transfer protein VPS13A

1

0

Small-scale

0.458

High

254850

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.445

High

774137

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.445

High

105462

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

327182

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.437

High

588053

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

767549

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

774133

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

774162

CK052
Uncharacterized protein C11orf52

1

3

High-throughput

0.437

High

774178

XPO7
Exportin-7

1

3

High-throughput

0.437

High

774177

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.347

High

289346

CTAG2
Cancer/testis antigen 2

1

0

High-throughput

0.279

Low

774152

LBH
Protein LBH

1

0

High-throughput

0.279

Low

774153

ESCO2
N-acetyltransferase ESCO2

1

0

High-throughput

0.279

Low

774157

A16A1
Aldehyde dehydrogenase family 16 member A1

1

0

High-throughput

0.279

Low

774164

INT4
Integrator complex subunit 4

1

0

High-throughput

0.279

Low

774174

SALL1
Sal-like protein 1

1

0

High-throughput

0.279

Low

774180

RP3A
Rabphilin-3A

1

0

Small-scale

0.261

Low

181690

CTDSL
CTD small phosphatase-like protein

1

0

High-throughput

0.249

Low

774163

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025