Protein: LEUK
Leukosialin (GPL115) (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43) [Cleaved into: CD43 cytoplasmic tail (CD43-ct) (CD43ct)]

Gene: LEUK, SPN
Organism: Homo sapiens
Interactions: 54
UniProt ID: P16150

Gene Ontology (top 5):
GO:0001562 - response to protozoan
GO:0001808 - negative regulation of type IV hypersensitivity
GO:0001931 - uropod
GO:0002296 - T-helper 1 cell lineage commitment
GO:0004888 - transmembrane signaling receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

480684

LEG1
Galectin-1

4

2

Small-scale

0.691

High

592733

S39AB
Zinc transporter ZIP11

3

0

High-throughput

0.638

High

592711

MOES
Moesin

2

1

Small-scale

0.629

High

592710

LEG3
Galectin-3

2

2

Small-scale

0.611

High

592745

EI2BG
Translation initiation factor eIF2B subunit gamma

3

1

High-throughput

0.609

High

243886

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

2

0

High-throughput

0.602

High

226695

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

0

High-throughput

0.580

High

592717

PLP2
Proteolipid protein 2

2

0

High-throughput

0.580

High

592748

UBQL2
Ubiquilin-2

2

0

High-throughput

0.580

High

592752

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

582653

EZRI
Ezrin

1

1

Small-scale

0.561

High

592712

CTNB1
Catenin beta-1

2

0

Small-scale

0.559

High

592716

EI2BB
Translation initiation factor eIF2B subunit beta

2

2

High-throughput

0.558

High

592719

EI2BE
Translation initiation factor eIF2B subunit epsilon

2

1

High-throughput

0.558

High

592749

EI2BD
Translation initiation factor eIF2B subunit delta

2

2

High-throughput

0.558

High

127271

LEG8
Galectin-8

1

2

High-throughput

0.536

High

592714

MTOR
Serine/threonine-protein kinase mTOR

1

3

High-throughput

0.536

High

592720

ATR
Serine/threonine-protein kinase ATR

1

1

High-throughput

0.536

High

592721

EI2BA
Translation initiation factor eIF2B subunit alpha

1

2

High-throughput

0.536

High

565548

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.513

High

592713

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.513

High

592723

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.513

High

592729

DYM
Dymeclin

1

0

High-throughput

0.513

High

592730

LIPB1
Liprin-beta-1

1

0

High-throughput

0.513

High

592731

CNDG2
Condensin-2 complex subunit G2

1

0

High-throughput

0.513

High

592734

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.513

High

592737

MYADM
Myeloid-associated differentiation marker

1

0

High-throughput

0.513

High

592739

NUP85
Nuclear pore complex protein Nup85

1

0

High-throughput

0.513

High

592744

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.513

High

592746

NCDN
Neurochondrin

1

0

High-throughput

0.513

High

592753

MA2B2
Epididymis-specific alpha-mannosidase

1

0

High-throughput

0.513

High

592750

IPO11
Importin-11

1

1

High-throughput

0.489

High

528658

PPGB
Lysosomal protective protein

1

1

High-throughput

0.481

High

592726

Q59EV6
Carboxypeptidase

1

1

High-throughput

0.470

High

592722

CLCA4
Calcium-activated chloride channel regulator 4

1

0

High-throughput

0.460

High

592743

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.460

High

592747

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.460

High

592715

PI4KA
Phosphatidylinositol 4-kinase alpha

1

2

High-throughput

0.445

High

592725

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

1

High-throughput

0.437

High

592751

DICER
Endoribonuclease Dicer

1

0

Small-scale

0.426

High

592736

SAAL1
Protein SAAL1

2

0

High-throughput

0.318

High

592724

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

592738

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.316

High

164521

TNPO2
Transportin-2

1

0

High-throughput

0.279

Low

592718

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.279

Low

592728

THADA
tRNA

1

0

High-throughput

0.279

Low

592732

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

0

High-throughput

0.279

Low

592735

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.279

Low

592740

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.279

Low

592741

XPO4
Exportin-4

1

0

High-throughput

0.279

Low

592742

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.279

Low

385422

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

221234

DCX
Neuronal migration protein doublecortin

1

0

Small-scale

0.249

Low

592727

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025