Protein: NUP85
Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1)

Gene: NUP85
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q9BW27

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005819 - spindle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1338936

NUP43
Nucleoporin Nup43

10

2

Small-scale

0.978

High

938279

SEC13
Protein SEC13 homolog

6

5

Small-scale

0.947

High

1388902

SEH1
Nucleoporin SEH1

5

5

Small-scale

0.918

High

1339092

NUP37
Nucleoporin Nup37

3

1

Small-scale

0.847

High

945308

NU107
Nuclear pore complex protein Nup107

8

1

Small-scale

0.748

High

1356932

NU133
Nuclear pore complex protein Nup133

5

1

Small-scale

0.706

High

916034

NUP98
Nuclear pore complex protein Nup98-Nup96

4

11

Small-scale

0.686

High

890394

NU153
Nuclear pore complex protein Nup153

3

10

High-throughput

0.656

High

1085278

NU160
Nuclear pore complex protein Nup160

3

1

Small-scale

0.650

High

1415841

SPAST
Spastin

3

0

High-throughput

0.634

High

285450

EED
Polycomb protein EED

1

2

High-throughput

0.618

High

1202232

DCAF6
DDB1- and CUL4-associated factor 6

1

1

High-throughput

0.618

High

1415830

NUP85
Nuclear pore complex protein Nup85

1

1

High-throughput

0.618

High

1415839

PD1L1
Programmed cell death 1 ligand 1

1

1

High-throughput

0.618

High

1134364

IMB1
Importin subunit beta-1

2

1

High-throughput

0.611

High

1326219

PNKD
Probable thioesterase PNKD

2

0

High-throughput

0.585

High

1415846

TN13B
Tumor necrosis factor ligand superfamily member 13B

2

0

High-throughput

0.585

High

775596

NU214
Nuclear pore complex protein Nup214

2

6

Small-scale

0.584

High

1415843

NUP50
Nuclear pore complex protein Nup50

2

4

High-throughput

0.584

High

1272425

GET4
Golgi to ER traffic protein 4 homolog

2

0

High-throughput

0.580

High

1249839

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.578

High

683331

TNR5
Tumor necrosis factor receptor superfamily member 5

2

0

High-throughput

0.576

High

1227382

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.575

High

242789

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

1114184

CUL3
Cullin-3

2

0

High-throughput

0.559

High

515804

RGPD1
RANBP2-like and GRIP domain-containing protein 1

1

5

High-throughput

0.536

High

849401

RANG
Ran-specific GTPase-activating protein

1

4

High-throughput

0.536

High

981676

RAN
GTP-binding nuclear protein Ran

1

1

High-throughput

0.536

High

1257891

UBP49
Ubiquitin carboxyl-terminal hydrolase 49

1

1

High-throughput

0.536

High

688129

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.518

High

262296

SCN2B
Sodium channel regulatory subunit beta-2

1

1

High-throughput

0.514

High

835497

CCR2
C-C chemokine receptor type 2

1

0

Small-scale

0.513

High

71244

HIDE1
Protein HIDE1

1

0

High-throughput

0.513

High

486610

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

592739

LEUK
Leukosialin

1

0

High-throughput

0.513

High

822164

PSB10
Proteasome subunit beta type-10

1

0

High-throughput

0.513

High

854269

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

993732

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.513

High

1134704

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.513

High

1150565

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.513

High

1152237

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1157491

PKN1
Serine/threonine-protein kinase N1

1

0

High-throughput

0.513

High

1291675

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

1415840

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.513

High

831360

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

628374

CD33
Myeloid cell surface antigen CD33

1

0

High-throughput

0.481

High

1293900

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

0

High-throughput

0.481

High

173303

XPO1
Exportin-1

1

2

Small-scale

0.479

High

291520

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.479

High

386181

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.479

High

487710

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

634608

LMNB1
Lamin-B1

1

2

High-throughput

0.479

High

789214

NUP62
Nuclear pore glycoprotein p62

1

5

High-throughput

0.479

High

832946

CETN2
Centrin-2

1

1

Small-scale

0.479

High

890581

RBP2
E3 SUMO-protein ligase RanBP2

1

1

High-throughput

0.479

High

955542

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.479

High

962436

RHOA
Transforming protein RhoA

1

1

High-throughput

0.479

High

1106060

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

1

High-throughput

0.479

High

1392785

P121A
Nuclear envelope pore membrane protein POM 121

1

4

High-throughput

0.479

High

1415833

UN45A
Protein unc-45 homolog A

1

1

High-throughput

0.479

High

1415842

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

129389

MEN1
Menin

1

0

High-throughput

0.458

High

159829

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

218717

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

223300

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

248071

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

272439

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

315970

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

363806

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

468755

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.458

High

611321

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

731582

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

791681

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

800082

COIL
Coilin

1

0

High-throughput

0.458

High

851808

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.458

High

854732

RAGP1
Ran GTPase-activating protein 1

1

0

High-throughput

0.458

High

879429

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

951397

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

965209

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

1005052

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1008320

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

High-throughput

0.458

High

1026531

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1029928

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

1140787

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1155719

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1161643

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1229663

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1280465

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1281603

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1289294

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.458

High

1329847

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1361675

ELYS
Protein ELYS

1

0

Small-scale

0.458

High

1367173

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1385613

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1396794

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1397394

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1399840

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1401375

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1405278

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.458

High

1409548

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.458

High

1415831

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.458

High

1415836

ANLN
Anillin

1

0

High-throughput

0.458

High

1415837

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1415838

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1415844

CAH14
Carbonic anhydrase 14

1

0

High-throughput

0.458

High

1415845

NUDC
Nuclear migration protein nudC

1

0

High-throughput

0.458

High

171570

S27A2
Long-chain fatty acid transport protein 2

1

3

High-throughput

0.445

High

1240950

S27A4
Long-chain fatty acid transport protein 4

1

3

High-throughput

0.445

High

1243658

S27A1
Long-chain fatty acid transport protein 1

1

3

High-throughput

0.445

High

1130424

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

1199676

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

1279079

RIC3
Protein RIC-3

1

0

High-throughput

0.426

High

1330740

SIGL1
SIGLEC family-like protein 1

1

0

High-throughput

0.426

High

166405

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

1

High-throughput

0.407

High

653548

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.407

High

1239543

ZNT6
Zinc transporter 6

1

1

High-throughput

0.407

High

1415847

S27A6
Long-chain fatty acid transport protein 6

1

3

High-throughput

0.407

High

1213040

CC183
Coiled-coil domain-containing protein 183

3

0

High-throughput

0.347

High

1232117

VASN
Vasorin

3

0

High-throughput

0.345

High

749269

CD70
CD70 antigen

2

0

High-throughput

0.328

High

1334407

UXS1
UDP-glucuronic acid decarboxylase 1

2

0

High-throughput

0.328

High

1248834

ENPP6
Glycerophosphocholine cholinephosphodiesterase ENPP6

2

0

High-throughput

0.318

High

1415848

NPTN
Neuroplastin

2

0

High-throughput

0.313

High

69829

ZN785
Zinc finger protein 785

1

0

High-throughput

0.279

Low

141788

MFNG
Beta-1,3-N-acetylglucosaminyltransferase manic fringe

1

0

High-throughput

0.279

Low

1022948

EFNB1
Ephrin-B1

1

0

High-throughput

0.279

Low

1387265

HDA11
Histone deacetylase 11

1

0

High-throughput

0.279

Low

1415832

FOXQ1
Forkhead box protein Q1

1

0

High-throughput

0.279

Low

1415834

CSTN2
Calsyntenin-2

1

0

High-throughput

0.279

Low

412545

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

903056

ZNF84
Zinc finger protein 84

1

0

High-throughput

0.249

Low

1135799

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

Small-scale

0.249

Low

1228798

FMN1
Formin-1

1

0

High-throughput

0.249

Low

1249183

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1255357

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1276733

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1324174

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

1336945

ZN740
Zinc finger protein 740

1

0

High-throughput

0.249

Low

1356869

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

High-throughput

0.249

Low

1386351

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

1415835

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025