Protein: PEA15
Astrocytic phosphoprotein PEA-15 (15 kDa phosphoprotein enriched in astrocytes) (Phosphoprotein enriched in diabetes) (PED)

Gene: PEA15
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q15121

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005875 - microtubule associated complex
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

703599

MK01
Mitogen-activated protein kinase 1

7

4

Small-scale

0.966

High

691745

MK03
Mitogen-activated protein kinase 3

5

4

Small-scale

0.928

High

908113

KS6A3
Ribosomal protein S6 kinase alpha-3

2

1

Small-scale

0.812

High

1096898

FADD
FAS-associated death domain protein

2

1

Small-scale

0.768

High

1132366

CASP8
Caspase-8

2

0

Small-scale

0.728

High

728248

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

Small-scale

0.691

High

193576

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

1

High-throughput

0.656

High

1115665

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

Small-scale

0.621

High

1103749

PLD1
Phospholipase D1

2

1

Small-scale

0.578

High

1142807

CSN5
COP9 signalosome complex subunit 5

1

0

Small-scale

0.549

High

1142822

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.549

High

1142782

MAPK3
MAP kinase-activated protein kinase 3

1

0

High-throughput

0.546

High

476697

RSSA
Small ribosomal subunit protein uS2

1

0

Small-scale

0.537

High

875671

PRC2A
Protein PRRC2A

1

1

High-throughput

0.536

High

1121674

SAFB2
Scaffold attachment factor B2

1

3

High-throughput

0.536

High

1142779

SAFB1
Scaffold attachment factor B1

1

3

High-throughput

0.536

High

1142789

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

1

High-throughput

0.536

High

1142821

SLTM
SAFB-like transcription modulator

1

2

High-throughput

0.536

High

1142824

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

1

High-throughput

0.536

High

270936

CLAP2
CLIP-associating protein 2

1

0

High-throughput

0.513

High

321842

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

0

High-throughput

0.513

High

529827

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

935515

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.513

High

961469

OSTN
Osteocrin

1

0

High-throughput

0.513

High

1124332

ELOA1
Elongin-A

1

0

High-throughput

0.513

High

1140066

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

1142781

TOM34
Mitochondrial import receptor subunit TOM34

1

0

High-throughput

0.513

High

1142786

HABP4
Intracellular hyaluronan-binding protein 4

1

0

High-throughput

0.513

High

1142787

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

0

High-throughput

0.513

High

1142796

ANR11
Ankyrin repeat domain-containing protein 11

1

0

High-throughput

0.513

High

1142798

DDX46
Probable ATP-dependent RNA helicase DDX46

1

0

High-throughput

0.513

High

1142800

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.513

High

1142801

LS14A
Protein LSM14 homolog A

1

0

High-throughput

0.513

High

1142803

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.513

High

1142804

GEMI5
Gem-associated protein 5

1

0

High-throughput

0.513

High

1142806

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.513

High

1142809

RRP36
Ribosomal RNA processing protein 36 homolog

1

0

High-throughput

0.513

High

1142817

ESF1
ESF1 homolog

1

0

High-throughput

0.513

High

1142819

DCA13
DDB1- and CUL4-associated factor 13

1

0

High-throughput

0.513

High

1142825

WBP11
WW domain-binding protein 11

1

0

High-throughput

0.513

High

1142827

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.513

High

188573

BCAT2
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

High-throughput

0.493

High

1142808

RMXL1
RNA binding motif protein, X-linked-like-1

1

1

High-throughput

0.489

High

63857

TPC13
Trafficking protein particle complex subunit 13

1

0

Small-scale

0.460

High

679165

DNJB1
DnaJ homolog subfamily B member 1

1

0

Small-scale

0.460

High

786331

PGM1
Phosphoglucomutase-1

1

0

Small-scale

0.460

High

791013

TALDO
Transaldolase

1

0

Small-scale

0.460

High

974131

RUXG
Small nuclear ribonucleoprotein G

1

0

Small-scale

0.460

High

1058836

ZO1
Tight junction protein 1

1

0

Small-scale

0.460

High

1142784

KLH12
Kelch-like protein 12

1

0

Small-scale

0.460

High

1142795

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

Small-scale

0.460

High

1142802

PAPD5
Terminal nucleotidyltransferase 4B

1

0

Small-scale

0.460

High

1142813

OSBL1
Oxysterol-binding protein-related protein 1

1

0

Small-scale

0.460

High

1142814

PUS3
tRNA pseudouridine(38/39) synthase

1

0

Small-scale

0.460

High

1142818

CYBP
Calcyclin-binding protein

1

0

Small-scale

0.460

High

1142823

RLP24
Probable ribosome biogenesis protein RLP24

1

0

Small-scale

0.460

High

345849

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

463968

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

0

High-throughput

0.458

High

675034

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

Small-scale

0.458

High

791397

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

897145

TNF10
Tumor necrosis factor ligand superfamily member 10

1

0

Small-scale

0.458

High

1142780

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1142788

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.458

High

1142805

FBF1
Fas-binding factor 1

1

0

High-throughput

0.458

High

1142791

KAD9
Adenylate kinase 9

1

0

High-throughput

0.438

High

1142820

PANK4
4'-phosphopantetheine phosphatase

1

0

High-throughput

0.438

High

168851

PLD2
Phospholipase D2

1

1

Small-scale

0.437

High

506133

PAB4L
Polyadenylate-binding protein 4-like

1

0

High-throughput

0.426

High

1142816

E41L1
Band 4.1-like protein 1

1

0

High-throughput

0.426

High

161135

ABCD4
Lysosomal cobalamin transporter ABCD4

1

0

High-throughput

0.282

High

731924

L1CAM
Neural cell adhesion molecule L1

1

0

High-throughput

0.282

High

1142826

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.282

High

1142783

MAP9
Microtubule-associated protein 9

1

0

High-throughput

0.279

Low

1142785

F133B
Protein FAM133B

1

0

High-throughput

0.279

Low

1142790

RBM26
RNA-binding protein 26

1

0

High-throughput

0.279

Low

1142792

PR38B
Pre-mRNA-splicing factor 38B

1

0

High-throughput

0.279

Low

1142810

DIDO1
Death-inducer obliterator 1

1

0

High-throughput

0.279

Low

1142794

SMYD5
Protein-lysine N-trimethyltransferase SMYD5

1

0

High-throughput

0.269

Low

615392

SON
Protein SON

1

0

Small-scale

0.251

Low

931366

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

0

Small-scale

0.251

Low

1142793

MYOME
Myomegalin

1

0

Small-scale

0.251

Low

1142799

CE120
Centrosomal protein of 120 kDa

1

0

Small-scale

0.251

Low

1142811

RAMAC
RNA guanine-N7 methyltransferase activating subunit

1

0

Small-scale

0.251

Low

1142815

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

Small-scale

0.251

Low

418144

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

1142797

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1142812

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025