Protein: LRC15
Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid homolog) (hLib)

Gene: LRC15, LRRC15
Organism: Homo sapiens
Interactions: 152
UniProt ID: Q8TF66

Gene Ontology (top 5):
GO:0001968 - fibronectin binding
GO:0005518 - collagen binding
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0016324 - apical plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

501776

RB40L
Ras-related protein Rab-40A-like

3

1

High-throughput

0.861

High

1353682

CLC11
C-type lectin domain family 11 member A

3

10

High-throughput

0.855

High

853833

MK09
Mitogen-activated protein kinase 9

3

0

High-throughput

0.816

High

1155370

RB11B
Ras-related protein Rab-11B

2

1

High-throughput

0.789

High

845240

GDF5
Growth/differentiation factor 5

2

0

High-throughput

0.770

High

1235477

IFIX
Pyrin and HIN domain-containing protein 1

3

0

High-throughput

0.720

High

366127

C1R
Complement C1r subcomponent

1

12

High-throughput

0.691

High

761273

RYK
Tyrosine-protein kinase RYK

1

20

High-throughput

0.691

High

1057104

FMOD
Fibromodulin

1

18

High-throughput

0.691

High

1353645

RB39B
Ras-related protein Rab-39B

1

2

High-throughput

0.691

High

1353661

SRMS
Tyrosine-protein kinase Srms

1

1

High-throughput

0.691

High

1353687

JAM1
Junctional adhesion molecule A

1

15

High-throughput

0.691

High

906570

PSMD7
26S proteasome non-ATPase regulatory subunit 7

3

1

High-throughput

0.667

High

1291846

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

3

1

High-throughput

0.667

High

1102952

ITAD
Integrin alpha-D

1

0

High-throughput

0.656

High

1353659

O51E2
Olfactory receptor 51E2

3

0

High-throughput

0.638

High

476176

ANXA5
Annexin A5

3

0

High-throughput

0.629

High

1340938

IL31R
Interleukin-31 receptor subunit alpha

2

6

High-throughput

0.628

High

1353684

S27A6
Long-chain fatty acid transport protein 6

2

7

High-throughput

0.628

High

1353683

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

19

High-throughput

0.618

High

908844

NEK2
Serine/threonine-protein kinase Nek2

1

1

Small-scale

0.618

High

292298

B3GL1
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

3

2

High-throughput

0.609

High

1308318

LACC1
Purine nucleoside phosphorylase LACC1

3

1

High-throughput

0.609

High

1353639

TFG
Protein TFG

3

2

High-throughput

0.609

High

1292609

GPBP1
Vasculin

2

0

High-throughput

0.602

High

1353685

KIF3A
Kinesin-like protein KIF3A

2

0

High-throughput

0.602

High

65359

TCAF2
TRPM8 channel-associated factor 2

2

0

High-throughput

0.585

High

1093483

COASY
Bifunctional coenzyme A synthase

2

0

High-throughput

0.585

High

1353677

CLC2D
C-type lectin domain family 2 member D

1

13

High-throughput

0.575

High

317202

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

2

3

High-throughput

0.574

High

942454

GSC
Homeobox protein goosecoid

2

3

High-throughput

0.574

High

1165340

SYT16
Synaptotagmin-16

2

1

High-throughput

0.574

High

1353662

HEAT1
HEAT repeat-containing protein 1

2

1

High-throughput

0.574

High

1353668

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

2

1

High-throughput

0.574

High

1353672

TBC14
TBC1 domain family member 14

2

1

High-throughput

0.574

High

1353679

FBXL4
F-box/LRR-repeat protein 4

2

20

High-throughput

0.574

High

296625

TNF13
Tumor necrosis factor ligand superfamily member 13

1

1

High-throughput

0.536

High

301813

ANXA9
Annexin A9

1

1

High-throughput

0.536

High

762412

BTC
Probetacellulin [Cleaved into: Betacellulin

1

1

High-throughput

0.536

High

835338

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

2

High-throughput

0.536

High

866763

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.536

High

867712

RGR
RPE-retinal G protein-coupled receptor

1

1

High-throughput

0.536

High

1087067

FSTL1
Follistatin-related protein 1

1

1

High-throughput

0.536

High

1250708

NPSR1
Neuropeptide S receptor

1

5

High-throughput

0.536

High

1295405

RFIP4
Rab11 family-interacting protein 4

1

6

High-throughput

0.536

High

1353671

NPAP1
Nuclear pore-associated protein 1

1

3

High-throughput

0.536

High

1353674

KS6B2
Ribosomal protein S6 kinase beta-2

1

0

High-throughput

0.517

High

762472

PROF2
Profilin-2

1

0

High-throughput

0.513

High

771638

DRD3
D(3) dopamine receptor

1

0

High-throughput

0.513

High

894432

MMP14
Matrix metalloproteinase-14

1

0

High-throughput

0.513

High

1111421

DGKZ
Diacylglycerol kinase zeta

1

0

High-throughput

0.513

High

1157298

PROL4
Proline-rich protein 4

1

0

High-throughput

0.513

High

1313628

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

1

0

High-throughput

0.513

High

1350289

C99L2
CD99 antigen-like protein 2

1

0

High-throughput

0.513

High

1353640

US6NL
USP6 N-terminal-like protein

1

0

High-throughput

0.513

High

1353647

DTBP1
Dysbindin

1

0

High-throughput

0.513

High

1353653

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

0

High-throughput

0.513

High

1353660

S26A1
Sulfate anion transporter 1

1

0

High-throughput

0.513

High

1353666

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

0

High-throughput

0.513

High

1353675

DKK2
Dickkopf-related protein 2

1

0

High-throughput

0.513

High

49401

DHR12
Dehydrogenase/reductase SDR family member 12

1

3

High-throughput

0.489

High

133872

FOXN3
Forkhead box protein N3

1

1

High-throughput

0.489

High

190079

FOXP2
Forkhead box protein P2

1

1

High-throughput

0.489

High

284188

SRS10
Serine/arginine-rich splicing factor 10

1

3

High-throughput

0.489

High

370733

FOS
Protein c-Fos

1

2

High-throughput

0.489

High

755501

ERD22
ER lumen protein-retaining receptor 2

1

1

High-throughput

0.489

High

876372

PTSS1
Phosphatidylserine synthase 1

1

1

High-throughput

0.489

High

1005546

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

1

High-throughput

0.489

High

1212719

TMTC4
Protein O-mannosyl-transferase TMTC4

1

1

High-throughput

0.489

High

1294660

CACL1
CDK2-associated and cullin domain-containing protein 1

1

5

High-throughput

0.489

High

1326812

CBR4
3-oxoacyl-[acyl-carrier-protein] reductase

1

1

High-throughput

0.489

High

1333805

RDH13
Retinol dehydrogenase 13

1

3

High-throughput

0.489

High

1336960

BHE23
Class E basic helix-loop-helix protein 23

1

1

High-throughput

0.489

High

1353636

RUFY2
RUN and FYVE domain-containing protein 2

1

4

High-throughput

0.489

High

1353651

SETB2
Histone-lysine N-methyltransferase SETDB2

1

2

High-throughput

0.489

High

1353669

SPTC3
Serine palmitoyltransferase 3

1

1

High-throughput

0.489

High

1353680

PNMA2
Paraneoplastic antigen Ma2

1

1

High-throughput

0.489

High

1353686

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

High-throughput

0.489

High

520607

RARA
Retinoic acid receptor alpha

1

1

Small-scale

0.479

High

934906

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

1155577

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.479

High

791568

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

914307

EFNA4
Ephrin-A4

1

0

High-throughput

0.458

High

328085

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

1

High-throughput

0.445

High

351932

S1PR4
Sphingosine 1-phosphate receptor 4

1

4

High-throughput

0.445

High

1353650

VPS35
Vacuolar protein sorting-associated protein 35

1

1

High-throughput

0.445

High

880044

DNSL1
Deoxyribonuclease-1-like 1

1

1

High-throughput

0.437

High

1219124

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

1

High-throughput

0.437

High

1241706

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.437

High

1353638

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

1353643

OTUL
Ubiquitin thioesterase otulin

1

1

High-throughput

0.437

High

261640

CATL2
Cathepsin L2

1

0

High-throughput

0.426

High

468640

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.426

High

733711

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

1

0

High-throughput

0.426

High

1333578

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.426

High

1353655

SYT11
Synaptotagmin-11

1

0

High-throughput

0.426

High

1353657

NAA50
N-alpha-acetyltransferase 50

1

0

High-throughput

0.426

High

252780

AP180
Clathrin coat assembly protein AP180

1

1

High-throughput

0.407

High

952261

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

1

High-throughput

0.407

High

1200946

SGO2
Shugoshin 2

3

0

High-throughput

0.347

High

1211604

TEX35
Testis-expressed protein 35

3

0

High-throughput

0.347

High

1295237

DOPP1
Dolichyldiphosphatase 1

3

0

High-throughput

0.347

High

1324695

ELMD1
ELMO domain-containing protein 1

3

0

High-throughput

0.347

High

1353648

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

3

0

High-throughput

0.347

High

303049

DFFB
DNA fragmentation factor subunit beta

2

0

High-throughput

0.328

High

418300

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.328

High

1081727

CF210
Cilia- and flagella- associated protein 210

2

0

High-throughput

0.328

High

1353634

CPLX3
Complexin-3

2

0

High-throughput

0.328

High

1353646

RM38
Large ribosomal subunit protein mL38

2

0

High-throughput

0.328

High

1353681

OAZ3
Ornithine decarboxylase antizyme 3

2

0

High-throughput

0.328

High

1353644

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.319

High

326752

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.279

Low

429133

7B2
Neuroendocrine protein 7B2

1

0

High-throughput

0.279

Low

469519

SYPH
Synaptophysin

1

0

High-throughput

0.279

Low

881728

FNTB
Protein farnesyltransferase subunit beta

1

0

High-throughput

0.279

Low

912205

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.279

Low

928745

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

1

0

High-throughput

0.279

Low

1203382

YIF1B
Protein YIF1B

1

0

High-throughput

0.279

Low

1206195

CX066
Uncharacterized protein CXorf66

1

0

High-throughput

0.279

Low

1250867

HEPN1
Putative cancer susceptibility gene HEPN1 protein

1

0

High-throughput

0.279

Low

1271323

CHST9
Carbohydrate sulfotransferase 9

1

0

High-throughput

0.279

Low

1287719

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

0

High-throughput

0.279

Low

1315338

THNS1
Threonine synthase-like 1

1

0

High-throughput

0.279

Low

1330602

PLD5
Inactive phospholipase D5

1

0

High-throughput

0.279

Low

1330816

TSYL6
Testis-specific Y-encoded-like protein 6

1

0

High-throughput

0.279

Low

1332356

IQUB
IQ motif and ubiquitin-like domain-containing protein

1

0

High-throughput

0.279

Low

1336013

TM35B
Transmembrane protein 35B

1

0

High-throughput

0.279

Low

1337404

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.279

Low

1351258

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

1

0

High-throughput

0.279

Low

1351817

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

1353642

VOPP1
WW domain binding protein VOPP1

1

0

High-throughput

0.279

Low

1353649

ZN597
Zinc finger protein 597

1

0

High-throughput

0.279

Low

1353652

MACD1
ADP-ribose glycohydrolase MACROD1

1

0

High-throughput

0.279

Low

1353654

ATGA1
Autophagy-related protein 101

1

0

High-throughput

0.279

Low

1353663

GEMI7
Gem-associated protein 7

1

0

High-throughput

0.279

Low

1353664

ZMAT4
Zinc finger matrin-type protein 4

1

0

High-throughput

0.279

Low

1353665

POPD2
Popeye domain-containing protein 2

1

0

High-throughput

0.279

Low

1353667

GP108
Protein GPR108

1

0

High-throughput

0.279

Low

1353673

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.279

Low

1353676

DPOG2
DNA polymerase subunit gamma-2

1

0

High-throughput

0.279

Low

1353678

FBX3
F-box only protein 3

1

0

High-throughput

0.279

Low

1287582

SETD3
Actin-histidine N-methyltransferase

1

0

High-throughput

0.269

Low

1096121

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.249

Low

1353637

RT27
Small ribosomal subunit protein mS27

1

0

High-throughput

0.249

Low

1353641

PMM1
Phosphomannomutase 1

1

0

High-throughput

0.249

Low

528493

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.232

Low

1193674

CERKL
Ceramide kinase-like protein

1

0

High-throughput

0.232

Low

1207734

TMM31
Transmembrane protein 31

1

0

High-throughput

0.232

Low

1353635

SKA2
Spindle and kinetochore-associated protein 2

1

0

High-throughput

0.232

Low

1353656

RM13
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.232

Low

1353658

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.232

Low

1353670

SPNXC
Sperm protein associated with the nucleus on the X chromosome C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025