Protein: NANOG
Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog)

Gene: NANOG
Organism: Homo sapiens
Interactions: 239
UniProt ID: Q9H9S0

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1334438

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

4

2

Small-scale

0.715

High

214375

SPOP
Speckle-type POZ protein

4

2

Small-scale

0.705

High

1309865

RHXF2
Rhox homeobox family member 2

1

19

High-throughput

0.698

High

686582

OTX2
Homeobox protein OTX2

1

18

High-throughput

0.618

High

1334417

NANOG
Homeobox protein NANOG

1

18

Small-scale

0.618

High

1334445

SATB2
DNA-binding protein SATB2

1

8

High-throughput

0.618

High

1273738

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

2

5

Small-scale

0.584

High

1334435

SALL4
Sal-like protein 4

2

20

Small-scale

0.584

High

1334450

ZN281
Zinc finger protein 281

2

12

Small-scale

0.584

High

542918

BRAF
Serine/threonine-protein kinase B-raf

1

4

Small-scale

0.561

High

929665

RACK1
Small ribosomal subunit protein RACK1

1

13

Small-scale

0.561

High

1334454

TRRAP
Transformation/transcription domain-associated protein

1

2

Small-scale

0.561

High

1274348

MED12
Mediator of RNA polymerase II transcription subunit 12

1

20

Small-scale

0.552

High

1311543

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.536

High

969113

KPCE
Protein kinase C epsilon type

1

5

Small-scale

0.501

High

1274243

RBPMS
RNA-binding protein with multiple splicing

1

4

High-throughput

0.481

High

157244

BACH1
Transcription regulator protein BACH1

1

7

Small-scale

0.479

High

162159

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

7

High-throughput

0.479

High

164272

ZN609
Zinc finger protein 609

1

20

High-throughput

0.479

High

170479

TIF1A
Transcription intermediary factor 1-alpha

1

13

High-throughput

0.479

High

178274

IPO8
Importin-8

1

2

High-throughput

0.479

High

234715

ZIC3
Zinc finger protein ZIC 3

1

9

High-throughput

0.479

High

243022

EDF1
Endothelial differentiation-related factor 1

1

2

High-throughput

0.479

High

245638

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

12

High-throughput

0.479

High

296142

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.479

High

313659

ZIC2
Zinc finger protein ZIC 2

1

11

High-throughput

0.479

High

328658

MBD3
Methyl-CpG-binding domain protein 3

1

3

High-throughput

0.479

High

374895

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

Small-scale

0.479

High

378850

HRG
Histidine-rich glycoprotein

1

7

High-throughput

0.479

High

428442

TBB5
Tubulin beta chain

1

4

High-throughput

0.479

High

477780

ZN865
Zinc finger protein 865

1

2

High-throughput

0.479

High

504778

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

525064

XRCC5
X-ray repair cross-complementing protein 5

1

8

High-throughput

0.479

High

539153

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

4

High-throughput

0.479

High

551281

ITF2
Transcription factor 4

1

4

High-throughput

0.479

High

565037

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.479

High

585071

RO52
E3 ubiquitin-protein ligase TRIM21

1

4

High-throughput

0.479

High

585933

WT1
Wilms tumor protein

1

8

High-throughput

0.479

High

649161

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

7

Small-scale

0.479

High

658737

SMCA1
Probable global transcription activator SNF2L1

1

20

High-throughput

0.479

High

675231

CLIP1
CAP-Gly domain-containing linker protein 1

1

4

High-throughput

0.479

High

680489

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

3

High-throughput

0.479

High

718207

BMI1
Polycomb complex protein BMI-1

1

20

High-throughput

0.479

High

718428

PCGF2
Polycomb group RING finger protein 2

1

20

High-throughput

0.479

High

751837

GRP75
Stress-70 protein, mitochondrial

1

3

High-throughput

0.479

High

789348

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.479

High

818476

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

828626

CENPF
Centromere protein F

1

7

High-throughput

0.479

High

832720

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

850260

ZN157
Zinc finger protein 157

1

2

High-throughput

0.479

High

872310

RD23B
UV excision repair protein RAD23 homolog B

1

4

High-throughput

0.479

High

878739

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

4

High-throughput

0.479

High

934485

CSK21
Casein kinase II subunit alpha

1

10

High-throughput

0.479

High

943092

PHC1
Polyhomeotic-like protein 1

1

20

High-throughput

0.479

High

963573

TIAR
Nucleolysin TIAR

1

3

High-throughput

0.479

High

999101

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

1019132

TP53B
TP53-binding protein 1

1

7

High-throughput

0.479

High

1019645

ILF2
Interleukin enhancer-binding factor 2

1

7

High-throughput

0.479

High

1027797

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

3

High-throughput

0.479

High

1028027

ERCC8
DNA excision repair protein ERCC-8

1

10

High-throughput

0.479

High

1028208

GPS2
G protein pathway suppressor 2

1

1

High-throughput

0.479

High

1031952

MTA1
Metastasis-associated protein MTA1

1

20

High-throughput

0.479

High

1035595

SMAD4
Mothers against decapentaplegic homolog 4

1

12

High-throughput

0.479

High

1036912

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

1038061

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

3

Small-scale

0.479

High

1042569

CUL3
Cullin-3

1

1

Small-scale

0.479

High

1043233

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

1045143

RUNX3
Runt-related transcription factor 3

1

3

High-throughput

0.479

High

1045944

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

1

6

Small-scale

0.479

High

1047915

CIRBP
Cold-inducible RNA-binding protein

1

5

High-throughput

0.479

High

1055165

HLTF
Helicase-like transcription factor

1

16

High-throughput

0.479

High

1059194

CBX2
Chromobox protein homolog 2

1

6

High-throughput

0.479

High

1063370

CND1
Condensin complex subunit 1

1

1

High-throughput

0.479

High

1063627

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1070781

RBBP5
Retinoblastoma-binding protein 5

1

7

High-throughput

0.479

High

1075253

TEAD2
Transcriptional enhancer factor TEF-4

1

3

High-throughput

0.479

High

1082400

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.479

High

1082541

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

1

High-throughput

0.479

High

1085684

HIF1A
Hypoxia-inducible factor 1-alpha

1

10

Small-scale

0.479

High

1092910

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

7

High-throughput

0.479

High

1121269

KLH22
Kelch-like protein 22

1

1

Small-scale

0.479

High

1127911

RRP12
RRP12-like protein

1

2

High-throughput

0.479

High

1129138

CYTSB
Cytospin-B

1

2

High-throughput

0.479

High

1139440

ECM29
Proteasome adapter and scaffold protein ECM29

1

2

High-throughput

0.479

High

1158322

CDC73
Parafibromin

1

1

High-throughput

0.479

High

1173242

PAXI1
PAX-interacting protein 1

1

18

High-throughput

0.479

High

1173879

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

2

High-throughput

0.479

High

1174660

H32
Histone H3.2

1

5

High-throughput

0.479

High

1175188

TBA1A
Tubulin alpha-1A chain

1

6

High-throughput

0.479

High

1192220

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

High-throughput

0.479

High

1193048

ZN467
Zinc finger protein 467

1

4

High-throughput

0.479

High

1199200

PB1
Protein polybromo-1

1

18

High-throughput

0.479

High

1201172

THOC4
THO complex subunit 4

1

5

High-throughput

0.479

High

1216155

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

4

High-throughput

0.479

High

1218101

ARI3B
AT-rich interactive domain-containing protein 3B

1

20

High-throughput

0.479

High

1219741

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

12

High-throughput

0.479

High

1219999

SUGP1
SURP and G-patch domain-containing protein 1

1

2

High-throughput

0.479

High

1230541

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

High-throughput

0.479

High

1244304

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

1245598

KDM2B
Lysine-specific demethylase 2B

1

4

High-throughput

0.479

High

1268792

RT31
Small ribosomal subunit protein mS31

1

1

High-throughput

0.479

High

1271542

JARD2
Protein Jumonji

1

16

High-throughput

0.479

High

1273074

FUBP2
Far upstream element-binding protein 2

1

6

High-throughput

0.479

High

1273886

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

High-throughput

0.479

High

1286410

ZN524
Zinc finger protein 524

1

5

High-throughput

0.479

High

1290503

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

1

High-throughput

0.479

High

1290632

PTCD3
Small ribosomal subunit protein mS39

1

1

High-throughput

0.479

High

1294306

SPF45
Splicing factor 45

1

2

High-throughput

0.479

High

1296844

EP400
E1A-binding protein p400

1

20

High-throughput

0.479

High

1299507

TREF1
Transcriptional-regulating factor 1

1

20

High-throughput

0.479

High

1300211

KI20B
Kinesin-like protein KIF20B

1

1

High-throughput

0.479

High

1302449

SIN3A
Paired amphipathic helix protein Sin3a

1

2

High-throughput

0.479

High

1304113

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1304758

SCAFB
Protein SCAF11

1

10

High-throughput

0.479

High

1306893

ARI3A
AT-rich interactive domain-containing protein 3A

1

20

High-throughput

0.479

High

1307570

AKAP9
A-kinase anchor protein 9

1

8

High-throughput

0.479

High

1312024

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.479

High

1314622

RBM4
RNA-binding protein 4

1

8

High-throughput

0.479

High

1314900

SSBP3
Single-stranded DNA-binding protein 3

1

16

High-throughput

0.479

High

1315136

SALL3
Sal-like protein 3

1

16

High-throughput

0.479

High

1315222

CECR2
Chromatin remodeling regulator CECR2

1

20

High-throughput

0.479

High

1318604

DPY30
Protein dpy-30 homolog

1

1

High-throughput

0.479

High

1326328

DDX24
ATP-dependent RNA helicase DDX24

1

4

High-throughput

0.479

High

1326818

PRD14
PR domain zinc finger protein 14

1

6

High-throughput

0.479

High

1327625

SP130
Histone deacetylase complex subunit SAP130

1

20

High-throughput

0.479

High

1328445

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

5

High-throughput

0.479

High

1328464

ING2
Inhibitor of growth protein 2

1

9

High-throughput

0.479

High

1332270

CCD86
Coiled-coil domain-containing protein 86

1

1

High-throughput

0.479

High

1334346

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

1

High-throughput

0.479

High

1334421

TF7L1
Transcription factor 7-like 1

1

20

High-throughput

0.479

High

1334422

SHCAF
SIN3-HDAC complex-associated factor

1

3

High-throughput

0.479

High

1334424

SALL1
Sal-like protein 1

1

16

High-throughput

0.479

High

1334428

BCLF1
Bcl-2-associated transcription factor 1

1

4

High-throughput

0.479

High

1334429

IBTK
Inhibitor of Bruton tyrosine kinase

1

5

High-throughput

0.479

High

1334431

TCF20
Transcription factor 20

1

19

High-throughput

0.479

High

1334432

DDX20
Probable ATP-dependent RNA helicase DDX20

1

2

High-throughput

0.479

High

1334437

ING1
Inhibitor of growth protein 1

1

11

High-throughput

0.479

High

1334439

GPTC8
G patch domain-containing protein 8

1

7

High-throughput

0.479

High

1334441

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

5

High-throughput

0.479

High

1334442

YETS2
YEATS domain-containing protein 2

1

11

High-throughput

0.479

High

1334443

AKP8L
A-kinase anchor protein 8-like

1

3

High-throughput

0.479

High

1334444

TRI33
E3 ubiquitin-protein ligase TRIM33

1

15

High-throughput

0.479

High

1334446

SMC3
Structural maintenance of chromosomes protein 3

1

6

High-throughput

0.479

High

1334452

RTCB
RNA-splicing ligase RtcB homolog

1

1

High-throughput

0.479

High

1334453

SALL2
Sal-like protein 2

1

15

High-throughput

0.479

High

1334455

SP16H
FACT complex subunit SPT16

1

4

High-throughput

0.479

High

1334456

TF3C3
General transcription factor 3C polypeptide 3

1

5

High-throughput

0.479

High

1334457

MAGD1
Melanoma-associated antigen D1

1

7

High-throughput

0.479

High

1334458

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.479

High

1334459

SOX21
Transcription factor SOX-21

1

20

High-throughput

0.479

High

136069

ACACB
Acetyl-CoA carboxylase 2

1

0

High-throughput

0.458

High

146869

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.458

High

210289

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

246281

NBN
Nibrin

1

0

High-throughput

0.458

High

327816

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

495618

THIO
Thioredoxin

1

0

High-throughput

0.458

High

664272

TPP2
Tripeptidyl-peptidase 2

1

0

High-throughput

0.458

High

795511

RAD52
DNA repair protein RAD52 homolog

1

0

High-throughput

0.458

High

837092

MRE11
Double-strand break repair protein MRE11

1

0

High-throughput

0.458

High

888219

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

949664

TXN4A
Thioredoxin-like protein 4A

1

0

High-throughput

0.458

High

966482

EXOSX
Exosome complex component 10

1

0

High-throughput

0.458

High

983515

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

0

High-throughput

0.458

High

1055798

ITPR3
Inositol 1,4,5-trisphosphate receptor type 3

1

0

High-throughput

0.458

High

1058554

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.458

High

1072311

ELOC
Elongin-C

1

0

High-throughput

0.458

High

1072964

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.458

High

1078357

MLF2
Myeloid leukemia factor 2

1

0

High-throughput

0.458

High

1129594

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.458

High

1158683

LTMD1
LETM1 domain-containing protein 1

1

0

High-throughput

0.458

High

1188093

HDX
Highly divergent homeobox

1

0

High-throughput

0.458

High

1198477

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.458

High

1204468

FBX11
F-box only protein 11

1

0

High-throughput

0.458

High

1219769

CDAN1
Codanin-1

1

0

High-throughput

0.458

High

1234257

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

High-throughput

0.458

High

1237671

PDCD7
Programmed cell death protein 7

1

0

High-throughput

0.458

High

1257335

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.458

High

1273319

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

1291634

TRM61
tRNA

1

0

High-throughput

0.458

High

1302560

CRBN
Protein cereblon

1

0

High-throughput

0.458

High

1326928

NAA50
N-alpha-acetyltransferase 50

1

0

High-throughput

0.458

High

1333915

VRTN
Vertnin

1

0

High-throughput

0.458

High

1334418

ELP3
Elongator complex protein 3

1

0

High-throughput

0.458

High

1334420

RESF1
Retroelement silencing factor 1

1

0

High-throughput

0.458

High

1334427

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.458

High

1334433

MUTYH
Adenine DNA glycosylase

1

0

High-throughput

0.458

High

1334434

TRM6
tRNA

1

0

High-throughput

0.458

High

1334436

APC4
Anaphase-promoting complex subunit 4

1

0

High-throughput

0.458

High

1334440

TF3C4
General transcription factor 3C polypeptide 4

1

0

High-throughput

0.458

High

1334449

NOP58
Nucleolar protein 58

1

0

High-throughput

0.458

High

1334460

CFA20
Cilia- and flagella-associated protein 20

1

0

High-throughput

0.458

High

1134770

LITD1
LINE-1 type transposase domain-containing protein 1

1

1

High-throughput

0.445

High

488808

ARAF
Serine/threonine-protein kinase A-Raf

1

4

Small-scale

0.437

High

560850

PDE6A
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

1

1

High-throughput

0.437

High

602000

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

3

High-throughput

0.437

High

603243

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

3

High-throughput

0.437

High

803980

NSF
Vesicle-fusing ATPase

1

2

High-throughput

0.437

High

838592

PPOX
Protoporphyrinogen oxidase

1

1

High-throughput

0.437

High

928820

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.437

High

947491

RT35
Small ribosomal subunit protein mS35

1

2

High-throughput

0.437

High

1138150

PR38B
Pre-mRNA-splicing factor 38B

1

4

High-throughput

0.437

High

1152318

TWF2
Twinfilin-2

1

1

High-throughput

0.437

High

1161986

GLD2
Poly(A) RNA polymerase GLD2

1

1

High-throughput

0.437

High

1164999

SAS6
Spindle assembly abnormal protein 6 homolog

1

3

High-throughput

0.437

High

1216764

TPPC5
Trafficking protein particle complex subunit 5

1

1

High-throughput

0.437

High

1232701

FBXW8
F-box/WD repeat-containing protein 8

1

15

Small-scale

0.437

High

1255693

RBCC1
RB1-inducible coiled-coil protein 1

1

5

High-throughput

0.437

High

1263870

MUC16
Mucin-16

1

20

High-throughput

0.437

High

1297875

PCMD1
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1

1

3

High-throughput

0.437

High

1300471

PRAM
PML-RARA-regulated adapter molecule 1

1

18

High-throughput

0.437

High

1334419

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

1

High-throughput

0.437

High

1334425

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

1

High-throughput

0.437

High

1334426

PCMD2
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2

1

3

High-throughput

0.437

High

1334430

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

6

High-throughput

0.437

High

1334447

COF2
Cofilin-2

1

1

High-throughput

0.437

High

1334448

MAN1
Inner nuclear membrane protein Man1

1

2

High-throughput

0.437

High

1334451

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

1

High-throughput

0.437

High

176860

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

0

High-throughput

0.249

Low

266825

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.249

Low

324048

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.249

Low

845883

RAB13
Ras-related protein Rab-13

1

0

High-throughput

0.249

Low

948508

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.249

Low

986443

P2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

1

0

High-throughput

0.249

Low

1033232

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.249

Low

1138114

ANGE2
Protein angel homolog 2

1

0

High-throughput

0.249

Low

1190482

TRPM1
Transient receptor potential cation channel subfamily M member 1

1

0

High-throughput

0.249

Low

1202863

AMZ2
Archaemetzincin-2

1

0

High-throughput

0.249

Low

1239906

GT251
Procollagen galactosyltransferase 1

1

0

High-throughput

0.249

Low

1241808

PDPR
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial

1

0

High-throughput

0.249

Low

1284583

RPE
Ribulose-phosphate 3-epimerase

1

0

High-throughput

0.249

Low

1287575

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.249

Low

1300630

PCD15
Protocadherin-15

1

0

High-throughput

0.249

Low

1315834

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.249

Low

1316505

RM09
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.249

Low

1317843

RM37
Large ribosomal subunit protein mL37

1

0

High-throughput

0.249

Low

1330720

TOR3A
Torsin-3A

1

0

High-throughput

0.249

Low

1332067

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

0

High-throughput

0.249

Low

1334423

LUC7L
Putative RNA-binding protein Luc7-like 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024