Protein: XYLK
Glycosaminoglycan xylosylkinase (EC 2.7.1.-) (Xylose kinase)

Gene: XYLK, FAM20B
Organism: Homo sapiens
Interactions: 96
UniProt ID: O75063

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus
GO:0016301 - kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

270047

P2RX4
P2X purinoceptor 4

4

1

High-throughput

0.691

High

270033

SPP2B
Signal peptide peptidase-like 2B

3

1

High-throughput

0.662

High

270052

GOLP3
Golgi phosphoprotein 3

3

1

Small-scale

0.660

High

270014

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

3

1

High-throughput

0.657

High

269999

PEX19
Peroxisomal biogenesis factor 19

3

0

High-throughput

0.638

High

269996

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

2

1

High-throughput

0.628

High

270028

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

2

1

High-throughput

0.628

High

270031

S7A14
Solute carrier family 7 member 14

2

2

High-throughput

0.606

High

270054

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.602

High

270037

S39A7
Zinc transporter SLC39A7

2

5

High-throughput

0.601

High

240254

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

270002

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.580

High

270056

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.580

High

270040

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

2

0

High-throughput

0.576

High

270042

SAAL1
Protein SAAL1

2

0

High-throughput

0.576

High

270051

GLP3L
Golgi phosphoprotein 3-like

1

1

Small-scale

0.561

High

270043

BSCL2
Seipin

2

1

High-throughput

0.560

High

194657

FFAR2
Free fatty acid receptor 2

2

2

High-throughput

0.553

High

270001

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

2

1

High-throughput

0.549

High

269993

V2R
Vasopressin V2 receptor

1

1

High-throughput

0.536

High

270005

P2RX1
P2X purinoceptor 1

1

1

High-throughput

0.536

High

270036

CLC2B
C-type lectin domain family 2 member B

1

2

High-throughput

0.536

High

270039

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

2

High-throughput

0.536

High

192527

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

270025

TM130
Transmembrane protein 130

1

0

High-throughput

0.513

High

270050

CENPH
Centromere protein H

1

0

High-throughput

0.513

High

270053

PHAX
Phosphorylated adapter RNA export protein

1

0

High-throughput

0.513

High

270057

B3GA2
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2

1

0

High-throughput

0.513

High

270065

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.513

High

269985

PGS2
Decorin

2

1

Small-scale

0.504

High

165870

FFAR1
Free fatty acid receptor 1

1

2

High-throughput

0.489

High

269990

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

2

High-throughput

0.489

High

270038

LPAR1
Lysophosphatidic acid receptor 1

1

2

High-throughput

0.489

High

270055

LPAR2
Lysophosphatidic acid receptor 2

1

2

High-throughput

0.489

High

160665

TOR1A
Torsin-1A

1

1

High-throughput

0.479

High

116992

J3KQ12
Seipin

1

1

High-throughput

0.470

High

178116

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

217600

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

269984

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

269987

UBL4A
Ubiquitin-like protein 4A

1

0

High-throughput

0.458

High

270006

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

270007

S35B1
Solute carrier family 35 member B1

1

1

High-throughput

0.445

High

270017

S39A4
Zinc transporter ZIP4

1

5

High-throughput

0.445

High

270023

S39AB
Zinc transporter ZIP11

1

5

High-throughput

0.445

High

270029

ZNT7
Zinc transporter 7

1

2

High-throughput

0.445

High

270030

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

1

High-throughput

0.445

High

270066

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

2

High-throughput

0.445

High

270019

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

159122

ABLM1
Actin-binding LIM protein 1

1

0

High-throughput

0.426

High

269997

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

Small-scale

0.426

High

270020

RIC3
Protein RIC-3

1

0

High-throughput

0.426

High

270048

TMM59
Transmembrane protein 59

1

0

High-throughput

0.426

High

270058

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

0

High-throughput

0.426

High

270063

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.426

High

269989

SDC1
Syndecan-1

1

1

Small-scale

0.407

High

269994

CTR1
High affinity cationic amino acid transporter 1

1

2

High-throughput

0.407

High

269995

SDC4
Syndecan-4

1

1

Small-scale

0.407

High

270003

S6A12
Sodium- and chloride-dependent betaine transporter

1

1

High-throughput

0.407

High

270004

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

1

High-throughput

0.407

High

270008

MFS10
Major facilitator superfamily domain-containing protein 10

1

1

High-throughput

0.407

High

270009

S39AE
Metal cation symporter ZIP14

1

5

High-throughput

0.407

High

270011

PAR14
Protein mono-ADP-ribosyltransferase PARP14

1

1

High-throughput

0.407

High

270022

S22A9
Organic anion transporter 7

1

1

High-throughput

0.407

High

270027

SVOP
Synaptic vesicle 2-related protein

1

1

High-throughput

0.407

High

270035

CTR3
Cationic amino acid transporter 3

1

2

High-throughput

0.407

High

270046

S1PR3
Sphingosine 1-phosphate receptor 3

1

2

High-throughput

0.407

High

269988

PVR
Poliovirus receptor

2

0

High-throughput

0.328

High

269998

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.328

High

270059

SCN3B
Sodium channel regulatory subunit beta-3

2

0

High-throughput

0.328

High

270061

DKKL1
Dickkopf-like protein 1

2

0

High-throughput

0.328

High

270012

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

270034

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.316

High

270044

TMM80
Transmembrane protein 80

2

0

High-throughput

0.316

High

269991

CD27
CD27 antigen

1

0

High-throughput

0.279

Low

269992

5HT1B
5-hydroxytryptamine receptor 1B

1

0

High-throughput

0.279

Low

270010

KR151
Keratin-associated protein 15-1

1

0

High-throughput

0.279

Low

270021

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

0

High-throughput

0.279

Low

270032

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

270049

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.279

Low

270000

PERI
Peripherin

1

0

High-throughput

0.249

Low

270018

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

270024

SYNE4
Nesprin-4

1

0

High-throughput

0.249

Low

270060

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

2083

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.232

Low

51017

PKHG3
Pleckstrin homology domain-containing family G member 3

1

0

High-throughput

0.232

Low

137159

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.232

Low

269986

SAP
Prosaposin

1

0

High-throughput

0.232

Low

270013

NTCP5
Sodium/bile acid cotransporter 5

1

0

High-throughput

0.232

Low

270015

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low

270016

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.232

Low

270026

SYNPO
Synaptopodin

1

0

High-throughput

0.232

Low

270041

CMBL
Carboxymethylenebutenolidase homolog

1

0

High-throughput

0.232

Low

270045

TM101
Transmembrane protein 101

1

0

High-throughput

0.232

Low

270062

EXOC7
Exocyst complex component 7

1

0

High-throughput

0.232

Low

270064

EXC6B
Exocyst complex component 6B

1

0

High-throughput

0.232

Low

270067

S4A4
Electrogenic sodium bicarbonate cotransporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025