Protein: MARH2
E3 ubiquitin-protein ligase MARCHF2 (EC 2.3.2.27) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II) (RING finger protein 172) (RING-type E3 ubiquitin transferase MARCHF2)

Gene: MARH2, MARCHF2
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q9P0N8

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1453943

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

3

1

Small-scale

0.677

High

1379888

FATE1
Fetal and adult testis-expressed transcript protein

3

2

High-throughput

0.675

High

1213723

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

4

1

High-throughput

0.637

High

564478

CFTR
Cystic fibrosis transmembrane conductance regulator

2

2

Small-scale

0.624

High

522749

PTPRF
Receptor-type tyrosine-protein phosphatase F

2

7

High-throughput

0.611

High

1384371

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

2

High-throughput

0.606

High

1416696

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

2

3

High-throughput

0.606

High

1452314

SCN3B
Sodium channel regulatory subunit beta-3

2

2

High-throughput

0.606

High

1453945

JAM1
Junctional adhesion molecule A

2

5

High-throughput

0.606

High

142115

PEX12
Peroxisome assembly protein 12

2

0

High-throughput

0.580

High

349642

TSN12
Tetraspanin-12

2

0

High-throughput

0.580

High

549906

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

590354

MUC1
Mucin-1

2

0

High-throughput

0.580

High

870806

CXA8
Gap junction alpha-8 protein

2

0

High-throughput

0.580

High

1216456

TSPO2
Translocator protein 2

2

0

High-throughput

0.580

High

1281769

T179B
Transmembrane protein 179B

2

0

High-throughput

0.580

High

1328820

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.580

High

1392016

PLPR2
Phospholipid phosphatase-related protein type 2

2

0

High-throughput

0.580

High

1415789

T106C
Transmembrane protein 106C

2

0

High-throughput

0.580

High

1453947

NEMO
NF-kappa-B essential modulator

1

2

Small-scale

0.561

High

1109081

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

1352542

GPX8
Probable glutathione peroxidase 8

2

1

High-throughput

0.553

High

163365

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

6

High-throughput

0.536

High

658940

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

7

High-throughput

0.536

High

690131

AVR2A
Activin receptor type-2A

1

8

High-throughput

0.536

High

1256361

AN13D
Ankyrin repeat domain-containing protein 13D

1

8

High-throughput

0.536

High

1446823

GPC5C
G-protein coupled receptor family C group 5 member C

1

0

High-throughput

0.513

High

508747

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

9

Small-scale

0.501

High

883345

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

19

Small-scale

0.501

High

906803

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

Small-scale

0.501

High

909401

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

Small-scale

0.501

High

971214

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

Small-scale

0.501

High

926861

VMAT1
Chromaffin granule amine transporter

1

1

High-throughput

0.481

High

226235

STX6
Syntaxin-6

1

6

Small-scale

0.479

High

245555

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

2

High-throughput

0.479

High

424278

S10A8
Protein S100-A8

1

2

High-throughput

0.479

High

445082

S10A9
Protein S100-A9

1

2

High-throughput

0.479

High

467634

4F2
Amino acid transporter heavy chain SLC3A2

1

4

High-throughput

0.479

High

592909

CBR1
Carbonyl reductase [NADPH] 1

1

3

High-throughput

0.479

High

880117

AL9A1
4-trimethylaminobutyraldehyde dehydrogenase

1

1

High-throughput

0.479

High

908057

VAMP7
Vesicle-associated membrane protein 7

1

5

High-throughput

0.479

High

1047763

NOTC2
Neurogenic locus notch homolog protein 2

1

5

High-throughput

0.479

High

1091586

DLG1
Disks large homolog 1

1

1

Small-scale

0.479

High

1125712

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.479

High

1158718

DPYL2
Dihydropyrimidinase-related protein 2

1

1

High-throughput

0.479

High

1403818

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.479

High

1407379

TM9S2
Transmembrane 9 superfamily member 2

1

1

High-throughput

0.479

High

1439573

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

3

Small-scale

0.479

High

1445739

WDR6
tRNA

1

1

High-throughput

0.479

High

1450119

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.479

High

1450457

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

2

High-throughput

0.479

High

1451736

OCAD1
OCIA domain-containing protein 1

1

2

High-throughput

0.479

High

1451782

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

3

High-throughput

0.479

High

1453942

CHPF2
Chondroitin sulfate glucuronyltransferase

1

1

High-throughput

0.479

High

1453944

FIS1
Mitochondrial fission 1 protein

1

1

High-throughput

0.479

High

167984

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

0

Small-scale

0.458

High

281685

MTX2
Metaxin-2

1

0

High-throughput

0.458

High

456287

CATD
Cathepsin D

1

0

High-throughput

0.458

High

458503

ADRB2
Beta-2 adrenergic receptor

1

0

Small-scale

0.458

High

713477

SPB3
Serpin B3

1

0

High-throughput

0.458

High

1164023

HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

1413681

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

0

High-throughput

0.458

High

275780

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

1

High-throughput

0.437

High

1312294

MIRO2
Mitochondrial Rho GTPase 2

1

3

High-throughput

0.437

High

1382968

S2546
Mitochondrial outer membrane protein SLC25A46

1

2

High-throughput

0.437

High

1453382

MTCH1
Mitochondrial carrier homolog 1

1

5

High-throughput

0.437

High

1453946

MTCH2
Mitochondrial carrier homolog 2

1

5

High-throughput

0.437

High

561049

CCL4
C-C motif chemokine 4

2

0

High-throughput

0.316

High

1195276

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.316

High

1207644

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1359332

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.316

High

1323898

SYNE4
Nesprin-4

1

0

High-throughput

0.299

High

1329449

KASH5
Protein KASH5

1

0

High-throughput

0.299

High

1010729

DCD
Dermcidin

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025