Protein: LEO1
RNA polymerase-associated protein LEO1

Gene: LEO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 66
UniProt ID: P38439

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0006325 - chromatin organization
GO:0006353 - DNA-templated transcription termination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748981

PAF1
RNA polymerase II-associated protein 1

11

7

Small-scale

0.977

High

750629

CTR9
RNA polymerase-associated protein CTR9

13

5

Small-scale

0.760

High

750639

CDC73
Cell division control protein 73

12

2

Small-scale

0.759

High

750622

RTF1
RNA polymerase-associated protein RTF1

11

2

Small-scale

0.758

High

750634

POB3
FACT complex subunit POB3

7

1

Small-scale

0.744

High

692768

SPT16
FACT complex subunit SPT16

10

0

Small-scale

0.721

High

558035

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

2

Small-scale

0.646

High

440025

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

Small-scale

0.614

High

425467

TFS2
Transcription elongation factor S-II

2

2

Small-scale

0.602

High

627990

SIS1
Protein SIS1

2

1

High-throughput

0.601

High

750628

H3
Histone H3

2

2

Small-scale

0.595

High

650285

SPT5
Transcription elongation factor SPT5

1

2

Small-scale

0.554

High

744131

ATR
Serine/threonine-protein kinase MEC1

1

0

Small-scale

0.537

High

750625

ELOA1
Elongin-A

1

0

Small-scale

0.537

High

703887

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

Small-scale

0.515

High

750612

LEO1
RNA polymerase-associated protein LEO1

1

1

High-throughput

0.515

High

750631

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

Small-scale

0.506

High

375377

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.501

High

410223

UBC2
Ubiquitin-conjugating enzyme E2 2

1

3

Small-scale

0.501

High

412736

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.501

High

550020

CSK21
Casein kinase II subunit alpha

1

1

Small-scale

0.501

High

614633

KC11
Casein kinase I homolog 1

1

2

High-throughput

0.501

High

614946

KC12
Casein kinase I homolog 2

1

2

High-throughput

0.501

High

697388

CHD1
Chromo domain-containing protein 1

1

4

Small-scale

0.501

High

701861

SWE1
Mitosis inhibitor protein kinase SWE1

1

1

High-throughput

0.501

High

750613

KSP1
Serine/threonine-protein kinase KSP1

1

2

High-throughput

0.501

High

419866

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.480

High

750632

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

0

High-throughput

0.480

High

339603

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.479

High

356448

H4
Histone H4

1

3

High-throughput

0.479

High

662099

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

663856

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.479

High

688215

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

696205

STH1
Nuclear protein STH1/NPS1

1

5

Small-scale

0.479

High

750614

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

1

Small-scale

0.479

High

750617

RAD26
DNA repair and recombination protein RAD26

1

6

Small-scale

0.479

High

750624

INO80
Chromatin-remodeling ATPase INO80

1

5

Small-scale

0.479

High

750627

ARP5
Actin-related protein 5

1

2

Small-scale

0.479

High

750633

RUVB1
RuvB-like protein 1

1

5

High-throughput

0.479

High

750636

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

750642

RUVB2
RuvB-like protein 2

1

5

High-throughput

0.479

High

750643

CMR1
DNA damage-binding protein CMR1

1

4

High-throughput

0.479

High

408346

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

604788

PSB4
Proteasome subunit beta type-4

1

0

Small-scale

0.458

High

634578

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

750619

IES1
Ino eighty subunit 1

1

0

Small-scale

0.458

High

750620

CLA4
Serine/threonine-protein kinase CLA4

1

0

Small-scale

0.458

High

750626

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

750635

HRQ1
ATP-dependent helicase HRQ1

1

0

Small-scale

0.458

High

750637

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

Small-scale

0.458

High

750638

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

750641

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

491077

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

493848

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

511150

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

746805

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.438

High

750615

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

750630

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

750616

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.407

High

648153

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.261

Low

750623

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

750618

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

750640

CRT10
Protein CRT10

1

0

Small-scale

0.249

Low

748336

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.238

Low

750621

GNP1
High-affinity glutamine permease

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024