Protein: PAF1
RNA polymerase II-associated protein 1 (Protein PAF1)

Gene: PAF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: P38351

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000183 - rDNA heterochromatin formation
GO:0000791 - euchromatin
GO:0000993 - RNA polymerase II complex binding
GO:0001015 - snoRNA transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748997

CTR9
RNA polymerase-associated protein CTR9

15

6

Small-scale

0.985

High

748981

LEO1
RNA polymerase-associated protein LEO1

11

7

Small-scale

0.977

High

440024

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

1

Small-scale

0.768

High

749009

CDC73
Cell division control protein 73

16

3

Small-scale

0.762

High

748991

RTF1
RNA polymerase-associated protein RTF1

14

2

Small-scale

0.761

High

692767

SPT16
FACT complex subunit SPT16

10

1

Small-scale

0.755

High

748980

PAF1
RNA polymerase II-associated protein 1

2

0

Small-scale

0.736

High

375376

RPB1
DNA-directed RNA polymerase II subunit RPB1

5

2

Small-scale

0.704

High

558034

RPB3
DNA-directed RNA polymerase II subunit RPB3

6

0

Small-scale

0.695

High

749004

POB3
FACT complex subunit POB3

6

2

Small-scale

0.667

High

650283

SPT5
Transcription elongation factor SPT5

2

2

Small-scale

0.621

High

606629

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.618

High

550019

CSK21
Casein kinase II subunit alpha

2

2

Small-scale

0.611

High

410222

UBC2
Ubiquitin-conjugating enzyme E2 2

2

1

Small-scale

0.595

High

748998

SEN1
Helicase SEN1

2

1

Small-scale

0.588

High

749000

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

1

Small-scale

0.573

High

339602

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.561

High

568874

HPR1
THO complex subunit HPR1

2

0

Small-scale

0.559

High

627985

SIS1
Protein SIS1

2

0

High-throughput

0.559

High

693918

MED18
Mediator of RNA polymerase II transcription subunit 18

2

0

Small-scale

0.559

High

748987

T2FB
Transcription initiation factor IIF subunit beta

2

0

Small-scale

0.547

High

744130

ATR
Serine/threonine-protein kinase MEC1

1

0

Small-scale

0.537

High

748994

ELOA1
Elongin-A

1

0

Small-scale

0.537

High

584721

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.515

High

425466

TFS2
Transcription elongation factor S-II

1

1

Small-scale

0.501

High

697387

CHD1
Chromo domain-containing protein 1

1

3

Small-scale

0.501

High

748996

H3
Histone H3

1

2

Small-scale

0.501

High

749010

BRE1
E3 ubiquitin-protein ligase BRE1

1

2

Small-scale

0.501

High

703885

PRS7
26S proteasome regulatory subunit 7 homolog

1

0

Small-scale

0.493

High

619141

SPT6
Transcription elongation factor SPT6

1

1

Small-scale

0.479

High

662089

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

663855

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.479

High

730787

CENPA
Histone H3-like centromeric protein CSE4

1

2

High-throughput

0.479

High

748983

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

1

Small-scale

0.479

High

748986

RAD26
DNA repair and recombination protein RAD26

1

3

Small-scale

0.479

High

748992

INO80
Chromatin-remodeling ATPase INO80

1

3

Small-scale

0.479

High

408344

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

586299

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

Small-scale

0.458

High

604787

PSB4
Proteasome subunit beta type-4

1

0

Small-scale

0.458

High

634575

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

680027

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

0

Small-scale

0.458

High

688214

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

689039

TFC1
Transcription factor tau 95 kDa subunit

1

0

High-throughput

0.458

High

691033

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.458

High

710164

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

Small-scale

0.458

High

748985

PHM8
Phosphate metabolism protein 8

1

0

High-throughput

0.458

High

748989

CLA4
Serine/threonine-protein kinase CLA4

1

0

Small-scale

0.458

High

748995

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

748999

RAGAB
GTP-binding protein GTR1

1

0

High-throughput

0.458

High

749001

TFB3
RNA polymerase II transcription factor B subunit 3

1

0

High-throughput

0.458

High

749002

DIG2
Down-regulator of invasive growth 2

1

0

High-throughput

0.458

High

749005

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

749006

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

Small-scale

0.458

High

749008

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

749012

NCBP2
Nuclear cap-binding protein subunit 2

1

0

Small-scale

0.458

High

749014

TAF10
Transcription initiation factor TFIID subunit 10

1

0

High-throughput

0.458

High

749015

CMR3
Zinc finger protein CRM3

1

0

High-throughput

0.458

High

749016

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

749017

YO342
Uncharacterized protein YOR342C

1

0

High-throughput

0.458

High

491067

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

493837

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

694603

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

675729

RENT1
ATP-dependent helicase NAM7

1

1

Small-scale

0.437

High

749003

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.437

High

511141

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

692505

ZUO1
Zuotin

1

0

High-throughput

0.426

High

748982

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

0

High-throughput

0.282

High

748984

RBG1
Ribosome-interacting GTPase 1

1

0

High-throughput

0.269

Low

748990

BRO1
Vacuolar-sorting protein BRO1

1

0

High-throughput

0.269

Low

749018

AYT1
Trichothecene 3-O-acetyltransferase

1

0

High-throughput

0.269

Low

749019

GLO4
Hydroxyacylglutathione hydrolase, mitochondrial

1

0

High-throughput

0.269

Low

498661

RT01
Small ribosomal subunit protein mS43

1

0

High-throughput

0.249

Low

543652

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

700866

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

734091

OMA1
Mitochondrial metalloendopeptidase OMA1

1

0

High-throughput

0.249

Low

740824

SOL2
6-phosphogluconolactonase-like protein 2

1

0

High-throughput

0.249

Low

748988

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

748993

SUN4
Probable secreted beta-glucosidase SUN4

1

0

High-throughput

0.249

Low

749007

YPQ2
Vacuolar arginine/histidine antiporter YPQ2

1

0

High-throughput

0.249

Low

749011

CRT10
Protein CRT10

1

0

Small-scale

0.249

Low

749013

PGC1
Phosphatidylglycerol phospholipase C

1

0

High-throughput

0.249

Low

588055

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low

705119

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024