Protein: NOP8
60S ribosome subunit biogenesis protein NOP8 (Nucleolar protein 8)

Gene: NOP8
Organism: Saccharomyces cerevisiae S288C
Interactions: 68
UniProt ID: Q08287

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0008428 - ribonuclease inhibitor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

758264

URB1
Nucleolar pre-ribosomal-associated protein 1

8

0

Small-scale

0.714

High

1062929

NIP7
60S ribosome subunit biogenesis protein NIP7

5

0

Small-scale

0.687

High

1053098

RSA3
Ribosome assembly protein 3

5

0

Small-scale

0.684

High

1062936

NOP58
Nucleolar protein 58

4

1

High-throughput

0.683

High

865426

URB2
Nucleolar pre-ribosomal-associated protein 2

4

0

Small-scale

0.648

High

923029

DBP6
ATP-dependent RNA helicase DBP6

4

0

Small-scale

0.643

High

1062933

MAK21
Ribosome biogenesis protein MAK21

3

1

Small-scale

0.640

High

814405

NOC2
Nucleolar complex protein 2

3

0

High-throughput

0.618

High

919025

PESC
Pescadillo homolog

3

0

Small-scale

0.613

High

1062935

NOP56
Nucleolar protein 56

2

1

High-throughput

0.601

High

798337

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

826896

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

830198

NOP2
25S rRNA

2

0

Small-scale

0.559

High

1025795

RAGAB
GTP-binding protein GTR1

2

0

Small-scale

0.551

High

722320

XPO1
Exportin-1

1

0

High-throughput

0.513

High

585395

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.493

High

677975

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.493

High

782471

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.493

High

509744

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

1055505

NOC4
Nucleolar complex protein 4

1

1

High-throughput

0.479

High

433881

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

435404

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

442143

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

512689

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

513418

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.458

High

570167

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

672970

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

674870

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

677594

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

708389

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

738271

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

0

High-throughput

0.458

High

748083

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

781661

DBP7
ATP-dependent RNA helicase DBP7

1

0

Small-scale

0.458

High

791122

NOP4
Nucleolar protein 4

1

0

High-throughput

0.458

High

792282

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

793541

MAK5
ATP-dependent RNA helicase MAK5

1

0

High-throughput

0.458

High

803955

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.458

High

804677

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.458

High

844645

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

919780

YG5X
Putative methyltransferase YGR283C

1

0

High-throughput

0.458

High

1033604

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

1037995

NU116
Nucleoporin NUP116/NSP116

1

0

High-throughput

0.458

High

1044800

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

1046067

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

1046812

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

1051618

HRQ1
ATP-dependent helicase HRQ1

1

0

Small-scale

0.458

High

1062926

SGO1
Shugoshin

1

0

High-throughput

0.458

High

1062927

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

1062928

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.458

High

1062930

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.458

High

1062931

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

1062932

RRP6
Exosome complex exonuclease RRP6

1

0

Small-scale

0.458

High

1062934

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.458

High

525376

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527869

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

393450

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

546548

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

1054901

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.426

High

504448

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

513256

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

751501

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.249

Low

753623

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

785988

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.249

Low

812722

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

918481

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

1046320

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.249

Low

1059378

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

1035154

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025