Protein: SYP1
Suppressor of yeast profilin deletion

Gene: SYP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 102
UniProt ID: P25623

Gene Ontology (top 5):
GO:0000144 - cellular bud neck septin ring
GO:0000147 - actin cortical patch assembly
GO:0001400 - mating projection base
GO:0004857 - enzyme inhibitor activity
GO:0005628 - prospore membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678070

SYP1
Suppressor of yeast profilin deletion

2

7

Small-scale

0.805

High

678088

EDE1
EH domain-containing and endocytosis protein 1

9

5

Small-scale

0.755

High

678082

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

4

2

Small-scale

0.700

High

678092

MID2
Cell wall integrity sensor MID2

3

6

Small-scale

0.668

High

678112

LSB3
LAS seventeen-binding protein 3

2

8

High-throughput

0.632

High

678078

CDC11
Cell division control protein 11

2

2

Small-scale

0.614

High

678141

LAS17
Proline-rich protein LAS17

2

4

Small-scale

0.614

High

649570

KCC2
Calcium/calmodulin-dependent protein kinase II

2

1

High-throughput

0.601

High

665782

KPC1
Protein kinase C-like 1

2

0

Small-scale

0.592

High

678140

PST2
Protoplast secreted protein 2

2

0

High-throughput

0.587

High

678097

ATG8
Autophagy-related protein 8

2

9

Small-scale

0.584

High

678077

RM09
Large ribosomal subunit protein uL3m

2

1

High-throughput

0.567

High

533160

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

1

4

High-throughput

0.541

High

678083

YSC84
Protein YSC84

1

6

High-throughput

0.541

High

678094

VRP1
Verprolin

1

7

High-throughput

0.541

High

678104

FLC2
Flavin carrier protein 2

1

1

High-throughput

0.541

High

678118

YG3A
Uncharacterized protein YGR130C

1

11

High-throughput

0.541

High

678119

AP18B
Clathrin coat assembly protein AP180B

1

2

High-throughput

0.541

High

678121

WSC2
Cell wall integrity and stress response component 2

1

7

High-throughput

0.541

High

678127

MYO5
Myosin-5

1

8

High-throughput

0.541

High

678129

ENT2
Epsin-2

1

2

High-throughput

0.541

High

678132

SHS1
Seventh homolog of septin 1

1

2

High-throughput

0.541

High

678134

FLC1
Flavin carrier protein 1

1

1

High-throughput

0.541

High

678120

FPK1
Flippase kinase 1

1

2

High-throughput

0.536

High

678081

ATC5
Phospholipid-transporting ATPase DNF1

1

0

High-throughput

0.518

High

678107

PRK1
Actin-regulating kinase PRK1

1

1

Small-scale

0.501

High

678111

BNI1
Protein BNI1

1

1

High-throughput

0.501

High

678122

ACT
Actin

1

9

Small-scale

0.501

High

678109

SA185
SIT4-associating protein SAP185

1

1

High-throughput

0.489

High

678137

PSH1
RING finger protein PSH1

1

2

High-throughput

0.489

High

678076

SNC1
Synaptobrevin homolog 1

1

0

Small-scale

0.480

High

149615

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

434866

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

435805

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

514485

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

578940

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

667074

CG22
G2/mitotic-specific cyclin-2

1

1

Small-scale

0.479

High

672217

CDC10
Cell division control protein 10

1

1

Small-scale

0.479

High

674447

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

678071

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

678086

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.479

High

678090

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

678095

GBLP
Small ribosomal subunit protein RACK1

1

10

High-throughput

0.479

High

678100

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

678102

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

678115

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

678123

NUM1
Nuclear migration protein NUM1

1

11

High-throughput

0.479

High

678073

CDC15
Cell division control protein 15

1

0

High-throughput

0.458

High

678079

CDC12
Cell division control protein 12

1

0

Small-scale

0.458

High

678085

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

678098

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

678099

FKS1
1,3-beta-glucan synthase component FKS1

1

0

Small-scale

0.458

High

678101

IF1A
Eukaryotic translation initiation factor 1A

1

0

High-throughput

0.458

High

678124

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

678131

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

678135

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

678138

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

526041

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

543978

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

678080

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

678105

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

678116

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

2

High-throughput

0.445

High

566487

DHAS
Aspartate-semialdehyde dehydrogenase

1

0

High-throughput

0.438

High

678106

JLP2
Protein JLP2

1

0

High-throughput

0.438

High

383088

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.437

High

383545

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

409961

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

433479

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

441735

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.437

High

454908

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

502879

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

504064

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

511145

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.437

High

512288

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

678072

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

678074

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

678084

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

678087

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

678091

CENPA
Histone H3-like centromeric protein CSE4

1

13

High-throughput

0.437

High

678096

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

678126

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.437

High

678128

RSE1
Pre-mRNA-splicing factor RSE1

1

2

High-throughput

0.437

High

678133

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

678139

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

625878

HNM1
Choline transporter

1

0

High-throughput

0.282

High

678089

SFK1
Protein SFK1

1

0

High-throughput

0.282

High

678125

PDR12
ATP-dependent permease PDR12

1

0

High-throughput

0.282

High

678093

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

678103

PRM9
Pheromone-regulated membrane protein 9

1

0

High-throughput

0.265

Low

427544

RLA1
Large ribosomal subunit protein P1A

1

0

High-throughput

0.249

Low

512849

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

548817

TAF13
Transcription initiation factor TFIID subunit 13

1

0

Small-scale

0.249

Low

677299

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

678075

SEC65
Signal recognition particle subunit SEC65

1

0

High-throughput

0.249

Low

678108

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

678110

MMM1
Maintenance of mitochondrial morphology protein 1

1

0

High-throughput

0.249

Low

678113

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

678117

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

678130

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

678136

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

0

High-throughput

0.249

Low

678114

VPS70
Vacuolar protein sorting-associated protein 70

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025