Protein: SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 (Synthetic lethal with MSS4 protein 1) (TORC2 effector protein SLM1)

Gene: SLM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 89
UniProt ID: P40485

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

825312

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

5

4

Small-scale

0.916

High

825325

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

4

4

Small-scale

0.878

High

825334

AVO2
Target of rapamycin complex 2 subunit AVO2

4

1

Small-scale

0.697

High

743395

TOR2
Serine/threonine-protein kinase TOR2

4

1

Small-scale

0.683

High

656320

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

3

5

Small-scale

0.641

High

554703

YPK1
Serine/threonine-protein kinase YPK1

3

0

Small-scale

0.629

High

825328

GLRX5
Monothiol glutaredoxin-5, mitochondrial

2

1

High-throughput

0.620

High

817723

TSC11
Target of rapamycin complex 2 subunit TSC11

3

0

Small-scale

0.613

High

798530

BIT2
Probable target of rapamycin complex 2 subunit BIT2

3

3

Small-scale

0.607

High

825313

MAM33
Mitochondrial acidic protein MAM33

2

0

High-throughput

0.587

High

825316

BIT61
Target of rapamycin complex 2 subunit BIT61

1

3

Small-scale

0.561

High

796269

RFS1
Protein RFS1

1

1

High-throughput

0.541

High

825345

PST2
Protoplast secreted protein 2

1

1

High-throughput

0.541

High

642401

MCK1
Protein kinase MCK1

1

2

High-throughput

0.536

High

820368

RIO2
Serine/threonine-protein kinase RIO2

1

4

High-throughput

0.536

High

825324

CBK1
Serine/threonine-protein kinase CBK1

1

1

High-throughput

0.536

High

825326

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

1

High-throughput

0.536

High

533176

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

1

0

High-throughput

0.518

High

625900

HNM1
Choline transporter

1

0

High-throughput

0.518

High

752065

DUR3
Urea active transporter

1

0

High-throughput

0.518

High

776727

SFK1
Protein SFK1

1

0

High-throughput

0.518

High

779857

MID2
Cell wall integrity sensor MID2

1

0

High-throughput

0.518

High

825318

MUP1
High-affinity methionine permease

1

0

High-throughput

0.518

High

825321

TPO2
Polyamine transporter 2

1

0

High-throughput

0.518

High

825329

PDR12
ATP-dependent permease PDR12

1

0

High-throughput

0.518

High

825341

FMP45
SUR7 family protein FMP45

1

0

High-throughput

0.518

High

822003

PSA4
Proteasome subunit alpha type-4

1

1

High-throughput

0.515

High

825338

RAD34
DNA repair protein RAD34

1

0

High-throughput

0.493

High

825343

RKM1
Ribosomal lysine N-methyltransferase 1

1

0

High-throughput

0.493

High

780550

SHE2
SWI5-dependent HO expression protein 2

1

0

High-throughput

0.486

High

825335

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

825339

YSP2
Membrane-anchored lipid-binding protein YSP2

1

0

High-throughput

0.486

High

575596

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

5

Small-scale

0.481

High

149802

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

436003

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

579525

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

674665

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

709806

BMH1
Protein BMH1

1

3

High-throughput

0.479

High

740947

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

2

High-throughput

0.479

High

747896

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

778365

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

792084

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

797747

AIM4
Altered inheritance of mitochondria protein 4

1

1

High-throughput

0.479

High

800801

RCK2
Serine/threonine-protein kinase RCK2

1

1

High-throughput

0.479

High

802209

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

825319

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

825327

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

825340

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.479

High

825346

LAS17
Proline-rich protein LAS17

1

1

Small-scale

0.479

High

667097

CG22
G2/mitotic-specific cyclin-2

1

0

Small-scale

0.458

High

795394

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

825317

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

825322

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.458

High

825330

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

825332

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

825336

TUS1
Rho1 guanine nucleotide exchange factor TUS1

1

0

Small-scale

0.458

High

825344

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

806965

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

3

High-throughput

0.445

High

825320

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.438

High

455102

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

512478

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

513046

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

670800

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

707297

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

795031

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

825314

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.437

High

825315

DSN1
Kinetochore-associated protein DSN1

1

3

High-throughput

0.437

High

825337

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.437

High

825342

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

656973

BUR1
Serine/threonine-protein kinase BUR1

1

0

High-throughput

0.269

Low

661416

PSA3
Proteasome subunit alpha type-3

1

0

High-throughput

0.269

Low

797398

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.269

Low

814139

SAW1
Single-strand annealing weakened protein 1

1

0

High-throughput

0.269

Low

825331

DOT1
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.269

Low

675292

DMC1
Meiotic recombination protein DMC1

1

0

High-throughput

0.265

Low

602126

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.251

Low

797110

CENPL
Inner kinetochore subunit IML3

1

0

High-throughput

0.251

Low

433680

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

441949

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

503083

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504250

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

557723

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.249

Low

689497

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

735512

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.249

Low

747407

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

753410

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

825333

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

825323

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025