Protein: MPP6
M-phase phosphoprotein 6 homolog (Exosome-associated RNA-binding protein MPP6)

Gene: MPP6
Organism: Saccharomyces cerevisiae S288C
Interactions: 48
UniProt ID: P53725

Gene Ontology (top 5):
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0008266 - poly(U) RNA binding
GO:0044877 - protein-containing complex binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

804733

RRP4
Exosome complex component RRP4

4

0

Small-scale

0.853

High

922959

RRP40
Exosome complex component RRP40

3

0

Small-scale

0.813

High

922963

RRP6
Exosome complex exonuclease RRP6

9

0

Small-scale

0.716

High

918878

RRP46
Exosome complex component RRP46

4

2

Small-scale

0.696

High

922954

RRP45
Exosome complex component RRP45

4

2

Small-scale

0.696

High

922965

RRP42
Exosome complex component RRP42

4

2

Small-scale

0.696

High

922945

CSL4
Exosome complex component CSL4

5

0

Small-scale

0.685

High

863120

RRP41
Exosome complex component SKI6

3

2

Small-scale

0.664

High

672925

RRP43
Exosome complex component RRP43

4

0

Small-scale

0.662

High

804944

LRP1
Exosome complex protein LRP1

4

0

Small-scale

0.653

High

922958

RRP44
Exosome complex exonuclease DIS3

4

0

Small-scale

0.653

High

871111

MTR3
Exosome complex component MTR3

3

0

Small-scale

0.636

High

921599

NRD1
Protein NRD1

2

0

Small-scale

0.616

High

864486

MTR4
ATP-dependent RNA helicase DOB1

2

0

Small-scale

0.559

High

922962

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.480

High

825624

AIR1
Protein AIR1

1

1

Small-scale

0.479

High

922967

AIR2
Protein AIR2

1

1

Small-scale

0.479

High

403605

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.458

High

444584

DED1
ATP-dependent RNA helicase DED1

1

0

Small-scale

0.458

High

531827

RL4A
Large ribosomal subunit protein uL4A

1

0

Small-scale

0.458

High

632813

DBP5
ATP-dependent RNA helicase DBP5

1

0

Small-scale

0.458

High

712633

RL8B
Large ribosomal subunit protein eL8B

1

0

Small-scale

0.458

High

806550

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

865148

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.458

High

922166

PAP2
Poly(A) RNA polymerase protein 2

1

0

Small-scale

0.458

High

922946

NOP13
Nucleolar protein 13

1

0

High-throughput

0.458

High

922952

RRP5
rRNA biogenesis protein RRP5

1

0

Small-scale

0.458

High

922956

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

922960

SKI7
Superkiller protein 7

1

0

High-throughput

0.458

High

922961

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

922964

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

922966

NOP56
Nucleolar protein 56

1

0

Small-scale

0.458

High

792889

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

922947

UTP17
NET1-associated nuclear protein 1

1

1

High-throughput

0.437

High

818422

DDI1
DNA damage-inducible protein 1

1

0

High-throughput

0.269

Low

677506

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

758393

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.249

Low

763601

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.249

Low

823367

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.249

Low

844558

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

919149

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.249

Low

922948

CCE1
Cruciform cutting endonuclease 1, mitochondrial

1

0

High-throughput

0.249

Low

922949

UTP5
U3 small nucleolar RNA-associated protein 5

1

0

High-throughput

0.249

Low

922950

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

922951

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.249

Low

922953

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.249

Low

922955

UTP13
U3 small nucleolar RNA-associated protein 13

1

0

High-throughput

0.249

Low

922957

UTP4
U3 small nucleolar RNA-associated protein 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025