Protein: UTP18
U3 small nucleolar RNA-associated protein 18 (U3 snoRNA-associated protein 18) (U three protein 18)

Gene: UTP18
Organism: Saccharomyces cerevisiae S288C
Interactions: 142
UniProt ID: P40362

Gene Ontology (top 5):
GO:0000292 - RNA fragment catabolic process
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678400

PWP2
Periodic tryptophan protein 2

14

2

Small-scale

0.983

High

823386

UTP13
U3 small nucleolar RNA-associated protein 13

7

2

High-throughput

0.965

High

823396

UTP4
U3 small nucleolar RNA-associated protein 4

7

3

Small-scale

0.963

High

823380

UTP15
U3 small nucleolar RNA-associated protein 15

4

1

High-throughput

0.892

High

823379

DHR1
Probable ATP-dependent RNA helicase DHR1

4

0

Small-scale

0.828

High

823376

UTP17
NET1-associated nuclear protein 1

2

4

High-throughput

0.789

High

823352

MTR4
ATP-dependent RNA helicase DOB1

2

0

Small-scale

0.773

High

823387

UTP21
U3 small nucleolar RNA-associated protein 21

15

4

Small-scale

0.764

High

632685

DBP4
ATP-dependent RNA helicase HCA4

2

0

High-throughput

0.753

High

823410

UTP12
U3 small nucleolar RNA-associated protein 12

8

3

Small-scale

0.752

High

823337

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.736

High

823373

UTP6
U3 small nucleolar RNA-associated protein 6

11

0

Small-scale

0.727

High

823346

UTP10
U3 small nucleolar RNA-associated protein 10

8

0

Small-scale

0.716

High

779130

DHR2
Probable ATP-dependent RNA helicase DHR2

1

0

High-throughput

0.713

High

823361

UTP22
U3 small nucleolar RNA-associated protein 22

6

0

High-throughput

0.707

High

823370

NAT10
RNA cytidine acetyltransferase

4

0

High-throughput

0.666

High

798232

ENP1
Essential nuclear protein 1

4

0

High-throughput

0.648

High

823393

NOC4
Nucleolar complex protein 4

4

0

Small-scale

0.648

High

677428

KRR1
KRR1 small subunit processome component

3

0

High-throughput

0.643

High

782071

RL1D1
Ribosome biogenesis protein UTP30

3

0

High-throughput

0.641

High

818307

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

3

0

High-throughput

0.641

High

585952

CSK21
Casein kinase II subunit alpha

2

2

High-throughput

0.633

High

823375

ELP3
Elongator complex protein 3

1

0

High-throughput

0.631

High

823354

MPP10
U3 small nucleolar RNA-associated protein MPP10

3

0

Small-scale

0.628

High

823381

UTP14
U3 small nucleolar RNA-associated protein 14

3

0

High-throughput

0.628

High

816509

SNU13
13 kDa ribonucleoprotein-associated protein

1

1

High-throughput

0.618

High

823392

RRP9
Ribosomal RNA-processing protein 9

1

3

High-throughput

0.618

High

823364

UTP8
U3 small nucleolar RNA-associated protein 8

3

0

Small-scale

0.613

High

585290

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

2

High-throughput

0.611

High

823382

RRP5
rRNA biogenesis protein RRP5

2

1

High-throughput

0.611

High

823413

NOP56
Nucleolar protein 56

2

1

High-throughput

0.611

High

747019

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

2

0

High-throughput

0.610

High

673186

RRP7
Ribosomal RNA-processing protein 7

2

0

High-throughput

0.588

High

823368

ESF2
Pre-rRNA-processing protein ESF2

2

0

High-throughput

0.588

High

823388

SGD1
Suppressor of glycerol defect protein 1

2

0

High-throughput

0.588

High

823391

ESF1
Pre-rRNA-processing protein ESF1

2

0

High-throughput

0.588

High

823408

SAS10
Something about silencing protein 10

2

0

High-throughput

0.588

High

823414

RRP36
rRNA biogenesis protein RRP36

2

0

High-throughput

0.588

High

823420

NOP14
Nucleolar complex protein 14

2

0

High-throughput

0.588

High

754289

DCA13
Protein SOF1

1

0

High-throughput

0.586

High

802867

DBP8
ATP-dependent RNA helicase DBP8

1

0

High-throughput

0.586

High

817578

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.586

High

823349

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.586

High

823357

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.586

High

823363

PESC
Pescadillo homolog

1

0

High-throughput

0.586

High

823412

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.586

High

758376

UTP11
U3 small nucleolar RNA-associated protein 11

2

0

High-throughput

0.585

High

823340

UTP25
U3 small nucleolar RNA-associated protein 25

2

0

Small-scale

0.585

High

823342

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

823405

UTP16
U3 small nucleolar RNA-associated protein 16

2

0

High-throughput

0.585

High

823421

PNO1
Pre-rRNA-processing protein PNO1

2

0

High-throughput

0.585

High

823378

UTP5
U3 small nucleolar RNA-associated protein 5

2

4

Small-scale

0.584

High

823415

NOP58
Nucleolar protein 58

2

1

High-throughput

0.584

High

513043

RS8A
Small ribosomal subunit protein eS8A

2

0

Small-scale

0.559

High

823369

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

823409

RRP6
Exosome complex exonuclease RRP6

2

0

High-throughput

0.559

High

622963

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.536

High

807766

CSK2C
Casein kinase II subunit beta'

1

1

High-throughput

0.536

High

823348

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.536

High

503079

RS22A
Small ribosomal subunit protein uS8A

2

1

High-throughput

0.533

High

823360

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.518

High

823365

NOP19
Nucleolar protein 19

1

0

High-throughput

0.518

High

823338

TCPE
T-complex protein 1 subunit epsilon

1

3

High-throughput

0.514

High

545102

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.504

High

818911

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.504

High

603486

VATA
V-type proton ATPase catalytic subunit A

1

1

High-throughput

0.489

High

441945

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

512476

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

804717

RRP4
Exosome complex component RRP4

1

1

High-throughput

0.479

High

823341

AIR1
Protein AIR1

1

1

Small-scale

0.479

High

823350

RRP41
Exosome complex component SKI6

1

3

High-throughput

0.479

High

823362

RRP46
Exosome complex component RRP46

1

3

High-throughput

0.479

High

823374

MLP1
Protein MLP1

1

1

High-throughput

0.479

High

823377

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

823384

RRP45
Exosome complex component RRP45

1

3

High-throughput

0.479

High

823400

RRP44
Exosome complex exonuclease DIS3

1

1

High-throughput

0.479

High

823411

RRP42
Exosome complex component RRP42

1

3

High-throughput

0.479

High

435134

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

670786

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

672897

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

689493

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

753407

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

763574

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

804618

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.458

High

804930

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

806528

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

808280

RRP8
25S rRNA

1

0

High-throughput

0.458

High

823339

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

823344

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

823353

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

823355

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

823356

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

823366

PXR1
Protein PXR1

1

0

Small-scale

0.458

High

823372

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

823383

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

823389

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

823394

BFR2
Protein BFR2

1

0

High-throughput

0.458

High

823398

CMS1
Protein CMS1

1

0

High-throughput

0.458

High

823399

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.458

High

823402

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

823406

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

823407

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

823417

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

823418

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

509587

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

1

High-throughput

0.457

High

709799

BMH1
Protein BMH1

1

1

High-throughput

0.437

High

823419

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.437

High

510548

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.407

High

524138

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.407

High

526850

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.407

High

741696

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.407

High

804205

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.407

High

816232

HSP7E
Heat shock protein SSC3, mitochondrial

1

2

High-throughput

0.407

High

823403

LPL1
Lipid droplet phospholipase 1

2

0

High-throughput

0.324

High

802514

SYSM
Serine--tRNA ligase, mitochondrial

2

0

High-throughput

0.307

High

750257

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.279

Low

782669

ESL2
EST/SMG-like protein 2

1

0

High-throughput

0.279

Low

823416

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.279

Low

484770

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

555094

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

823345

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.261

Low

823358

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.261

Low

823401

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

707273

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

795021

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

812363

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

823343

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

823359

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

823367

MPP6
M-phase phosphoprotein 6 homolog

1

0

High-throughput

0.249

Low

823371

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

823385

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low

823390

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

823397

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

823404

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

592289

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

631940

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.232

Low

752332

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

811323

CAJ1
Protein CAJ1

1

0

High-throughput

0.232

Low

823347

ERJ5
ER-localized J domain-containing protein 5

1

0

High-throughput

0.232

Low

823351

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

823395

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025