Protein: LRP1
Exosome complex protein LRP1 (Like an rRNA processing protein 1) (Yeast C1D domain-containing protein) (rRNA processing protein 47)

Gene: LRP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 78
UniProt ID: P38801

Gene Ontology (top 5):
GO:0000178 - exosome (RNase complex)
GO:0000460 - maturation of 5.8S rRNA
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

804974

RRP6
Exosome complex exonuclease RRP6

19

0

Small-scale

0.935

High

804942

RRP46
Exosome complex component RRP46

6

2

Small-scale

0.729

High

804967

RRP44
Exosome complex exonuclease DIS3

8

0

Small-scale

0.716

High

804711

RRP4
Exosome complex component RRP4

6

0

Small-scale

0.702

High

804945

CSL4
Exosome complex component CSL4

6

0

Small-scale

0.691

High

804958

RRP45
Exosome complex component RRP45

4

2

Small-scale

0.683

High

804944

MPP6
M-phase phosphoprotein 6 homolog

4

0

Small-scale

0.653

High

672884

RRP43
Exosome complex component RRP43

4

0

Small-scale

0.648

High

804925

LRP1
Exosome complex protein LRP1

3

0

Small-scale

0.623

High

804978

NOP56
Nucleolar protein 56

2

1

Small-scale

0.584

High

804979

NOP58
Nucleolar protein 58

2

1

Small-scale

0.584

High

804939

MTR3
Exosome complex component MTR3

2

0

High-throughput

0.576

High

677387

KRR1
KRR1 small subunit processome component

2

0

High-throughput

0.559

High

798209

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

804934

UTP10
U3 small nucleolar RNA-associated protein 10

2

0

High-throughput

0.559

High

804952

DHR1
Probable ATP-dependent RNA helicase DHR1

2

0

High-throughput

0.559

High

804955

UTP14
U3 small nucleolar RNA-associated protein 14

2

0

High-throughput

0.559

High

804963

NOC4
Nucleolar complex protein 4

2

0

High-throughput

0.559

High

804968

RRP40
Exosome complex component RRP40

2

0

High-throughput

0.559

High

666450

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.518

High

700238

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.518

High

656458

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.480

High

678389

PWP2
Periodic tryptophan protein 2

1

1

High-throughput

0.479

High

804935

RRP41
Exosome complex component SKI6

1

2

High-throughput

0.479

High

804936

MTR4
ATP-dependent RNA helicase DOB1

1

1

High-throughput

0.479

High

804949

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.479

High

804951

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.479

High

804959

UTP13
U3 small nucleolar RNA-associated protein 13

1

2

High-throughput

0.479

High

804960

UTP21
U3 small nucleolar RNA-associated protein 21

1

2

High-throughput

0.479

High

804965

UTP4
U3 small nucleolar RNA-associated protein 4

1

1

High-throughput

0.479

High

804976

UTP12
U3 small nucleolar RNA-associated protein 12

1

2

High-throughput

0.479

High

804977

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

523867

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.458

High

646393

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

673173

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

679651

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

707029

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

747014

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

0

High-throughput

0.458

High

754275

DCA13
Protein SOF1

1

0

High-throughput

0.458

High

758369

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

763568

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

804926

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

804927

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

804929

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.458

High

804930

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.458

High

804931

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

804932

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

804933

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

804937

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.458

High

804938

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

804941

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.458

High

804943

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

804946

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.458

High

804947

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

804948

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

804950

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

804953

UTP15
U3 small nucleolar RNA-associated protein 15

1

0

High-throughput

0.458

High

804956

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.458

High

804957

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

804961

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

804962

RRP9
Ribosomal RNA-processing protein 9

1

0

High-throughput

0.458

High

804964

BFR2
Protein BFR2

1

0

High-throughput

0.458

High

804966

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.458

High

804969

SKI7
Superkiller protein 7

1

0

High-throughput

0.458

High

804970

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

804971

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

804972

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

804973

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

804975

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

804980

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

804981

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.458

High

804982

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

544790

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

804940

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

804928

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

752229

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

804954

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025