Protein: DBP5
ATP-dependent RNA helicase DBP5 (EC 3.6.4.13) (DEAD box protein 5) (Helicase CA5/6) (Ribonucleic acid-trafficking protein 8)

Gene: DBP5
Organism: Saccharomyces cerevisiae S288C
Interactions: 79
UniProt ID: P20449

Gene Ontology (top 5):
GO:0003724 - RNA helicase activity
GO:0003729 - mRNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

632835

GLE1
mRNA export factor GLE1

7

6

Small-scale

0.976

High

632803

NU159
Nucleoporin NUP159

5

12

Small-scale

0.932

High

632825

GFD1
mRNA transport factor GFD1

4

0

Small-scale

0.664

High

632837

MEX67
mRNA export factor MEX67

3

4

Small-scale

0.664

High

434817

RS3
Small ribosomal subunit protein uS3

3

2

Small-scale

0.640

High

518198

IF4A
ATP-dependent RNA helicase eIF4A

1

17

High-throughput

0.618

High

632782

SPB4
ATP-dependent rRNA helicase SPB4

1

17

High-throughput

0.618

High

632809

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.618

High

632823

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.618

High

632828

SUB2
ATP-dependent RNA helicase SUB2

1

18

High-throughput

0.618

High

403351

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

12

Small-scale

0.601

High

449316

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD/RAD3

1

0

Small-scale

0.586

High

632777

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.586

High

578827

HSC82
ATP-dependent molecular chaperone HSC82

2

4

High-throughput

0.584

High

632785

XPO1
Exportin-1

2

16

Small-scale

0.584

High

632786

HS104
Heat shock protein 104

2

3

High-throughput

0.584

High

632806

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

17

High-throughput

0.584

High

553579

ERF1
Eukaryotic peptide chain release factor subunit 1

2

0

Small-scale

0.559

High

632807

SAC3
Nuclear mRNA export protein SAC3

2

0

Small-scale

0.559

High

632788

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

2

Small-scale

0.552

High

632811

ZDS1
Protein ZDS1

1

2

Small-scale

0.552

High

632787

MKK2
MAP kinase kinase MKK2/SSP33

1

20

High-throughput

0.536

High

632804

MOB1
DBF2 kinase activator protein MOB1

1

1

High-throughput

0.536

High

517890

SSBP1
Single-stranded nucleic acid-binding protein

1

12

High-throughput

0.501

High

632810

NUP42
Nucleoporin NUP42

1

5

Small-scale

0.501

High

392211

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.479

High

438122

NOT2
General negative regulator of transcription subunit 2

1

2

Small-scale

0.479

High

515206

RL35A
Large ribosomal subunit protein uL29A

1

1

Small-scale

0.479

High

554663

YPK1
Serine/threonine-protein kinase YPK1

1

11

High-throughput

0.479

High

558577

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

632776

VPS1
Vacuolar protein sorting-associated protein 1

1

2

High-throughput

0.479

High

632778

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

632780

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

632781

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

632784

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

632790

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

632793

NU170
Nucleoporin NUP170

1

1

High-throughput

0.479

High

632795

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

632796

NMD3
60S ribosomal export protein NMD3

1

1

Small-scale

0.479

High

632797

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

632798

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

632800

YEY6
MYG1 protein YER156C

1

1

Small-scale

0.479

High

632801

RIO2
Serine/threonine-protein kinase RIO2

1

9

Small-scale

0.479

High

632802

MLP2
Protein MLP2

1

14

High-throughput

0.479

High

632812

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.479

High

632815

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

632817

MLP1
Protein MLP1

1

12

High-throughput

0.479

High

632820

RLI1
Translation initiation factor RLI1

1

3

Small-scale

0.479

High

632824

SIZ1
E3 SUMO-protein ligase SIZ1

1

4

High-throughput

0.479

High

632826

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

632832

YRA1
RNA annealing protein YRA1

1

16

High-throughput

0.479

High

632833

RIO1
Serine/threonine-protein kinase RIO1

1

9

High-throughput

0.479

High

632834

SIZ2
E3 SUMO-protein ligase SIZ2

1

4

High-throughput

0.479

High

531240

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.458

High

632775

CCA1
CCA tRNA nucleotidyltransferase, mitochondrial

1

0

High-throughput

0.458

High

632779

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.458

High

632789

TFB1
General transcription and DNA repair factor IIH subunit TFB1

1

0

Small-scale

0.458

High

632794

SDS24
Protein SDS24

1

0

High-throughput

0.458

High

632808

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

632813

MPP6
M-phase phosphoprotein 6 homolog

1

0

Small-scale

0.458

High

632814

NRK1
Nicotinamide riboside kinase

1

0

High-throughput

0.458

High

632819

ESP1
Separin

1

0

High-throughput

0.458

High

632821

HOT1
High-osmolarity-induced transcription protein 1

1

0

Small-scale

0.458

High

632822

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

632827

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

632831

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

632816

UBC7
Ubiquitin-conjugating enzyme E2 7

1

4

High-throughput

0.457

High

543788

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.445

High

632791

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

632799

HSP7E
Heat shock protein SSC3, mitochondrial

1

11

High-throughput

0.445

High

409931

RL25
Large ribosomal subunit protein uL23

1

3

Small-scale

0.437

High

454871

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.437

High

632783

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.437

High

632792

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

632829

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

632830

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

632836

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.426

High

632805

DJP1
DnaJ-like protein 1

1

3

High-throughput

0.407

High

632818

TFB2
General transcription and DNA repair factor IIH subunit TFB2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025