Protein: SEC16
COPII coat assembly protein SEC16 (Protein transport protein SEC16)

Gene: SEC16
Organism: Saccharomyces cerevisiae S288C
Interactions: 93
UniProt ID: P48415

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0007030 - Golgi organization
GO:0012507 - ER to Golgi transport vesicle membrane
GO:0015031 - protein transport
GO:0016236 - macroautophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

871858

SEC13
Protein transport protein SEC13

7

0

Small-scale

0.909

High

808380

SEC31
Protein transport protein SEC31

3

0

Small-scale

0.835

High

673059

SED4
Putative guanine nucleotide-exchange factor SED4

2

0

Small-scale

0.784

High

582487

SEC23
Protein transport protein SEC23

9

2

Small-scale

0.755

High

825225

SEC24
Protein transport protein SEC24

6

3

Small-scale

0.735

High

871853

SFB2
SED5-binding protein 2

3

3

Small-scale

0.653

High

871848

SEC16
COPII coat assembly protein SEC16

1

0

Small-scale

0.589

High

871851

COPA
Coatomer subunit alpha

1

0

Small-scale

0.519

High

843173

PFS2
Polyadenylation factor subunit 2

1

0

High-throughput

0.517

High

871867

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.517

High

597197

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

527105

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.504

High

823158

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.493

High

432628

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.489

High

633559

SAR1
Small COPII coat GTPase SAR1

1

0

Small-scale

0.480

High

805165

SFB3
SED5-binding protein 3

1

3

High-throughput

0.479

High

825660

COPE
Coatomer subunit epsilon

1

0

Small-scale

0.460

High

438731

SC160
Protein SCP160

1

0

High-throughput

0.458

High

575973

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.458

High

679848

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

747937

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

781215

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.458

High

812462

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

871861

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

419458

H2A1
Histone H2A.1

1

1

High-throughput

0.437

High

419800

H2A2
Histone H2A.2

1

1

High-throughput

0.437

High

709865

BMH1
Protein BMH1

1

1

High-throughput

0.437

High

760297

BMH2
Protein BMH2

1

1

High-throughput

0.437

High

871865

LAS17
Proline-rich protein LAS17

1

1

Small-scale

0.437

High

676141

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

820914

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.426

High

367068

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.407

High

524476

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

531798

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.407

High

545473

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

592354

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

819196

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

871849

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.407

High

871864

RL7B
Large ribosomal subunit protein uL30B

1

1

High-throughput

0.407

High

825283

MOB1
DBF2 kinase activator protein MOB1

2

0

High-throughput

0.318

High

795445

ATG8
Autophagy-related protein 8

2

0

High-throughput

0.305

High

382201

H4
Histone H4

2

0

High-throughput

0.298

High

579704

HSC82
ATP-dependent molecular chaperone HSC82

2

0

High-throughput

0.298

High

722078

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

805466

DMA1
E3 ubiquitin-protein ligase DMA1

1

0

High-throughput

0.279

Low

835827

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.279

Low

796399

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.269

Low

820479

MMF1
Protein MMF1, mitochondrial

1

0

High-throughput

0.269

Low

518072

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.261

Low

689072

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.249

Low

707573

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

727164

HS104
Heat shock protein 104

1

0

High-throughput

0.249

Low

758189

ZRT3
Zinc-regulated transporter 3

1

0

High-throughput

0.249

Low

797759

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

809359

STM1
Suppressor protein STM1

1

0

High-throughput

0.249

Low

812078

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.249

Low

824742

MLP2
Protein MLP2

1

0

High-throughput

0.249

Low

824911

TM108
Protein TMA108

1

0

High-throughput

0.249

Low

863906

TOH1
Probable circularly permuted 1,3-beta-glucanase YJL171C

1

0

High-throughput

0.249

Low

865313

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.249

Low

865664

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

871850

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

871854

H3
Histone H3

1

0

High-throughput

0.249

Low

871855

MCE1
mRNA-capping enzyme subunit alpha

1

0

High-throughput

0.249

Low

871856

SED1
Cell wall protein SED1

1

0

High-throughput

0.249

Low

871857

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.249

Low

871859

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

871860

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.249

Low

871862

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

871863

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.249

Low

871866

RAX2
Bud site selection protein RAX2

1

0

High-throughput

0.249

Low

358267

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

365655

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.232

Low

383329

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.232

Low

386776

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

394704

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

427348

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

433240

RL17A
Large ribosomal subunit protein uL22A

1

0

High-throughput

0.232

Low

436052

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.232

Low

439378

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.232

Low

453678

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

486244

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.232

Low

511821

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.232

Low

570275

RS17B
Small ribosomal subunit protein eS17B

1

0

High-throughput

0.232

Low

622379

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.232

Low

684774

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.232

Low

801074

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.232

Low

802654

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.232

Low

824479

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.232

Low

836780

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

850541

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

High-throughput

0.232

Low

871852

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025