Protein: LCAP
Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form]

Gene: LCAP, LNPEP
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q9UIQ6

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0002480 - antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0004177 - aminopeptidase activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1329539

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

4

2

Small-scale

0.709

High

654885

CALX
Calnexin

4

3

High-throughput

0.691

High

119557

LEG9
Galectin-9

3

5

High-throughput

0.667

High

121227

LEG8
Galectin-8

3

5

High-throughput

0.667

High

354785

DRA
HLA class II histocompatibility antigen, DR alpha chain

3

8

High-throughput

0.667

High

572475

LEG3
Galectin-3

3

5

High-throughput

0.667

High

588827

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

3

8

High-throughput

0.667

High

1166314

BTNL8
Butyrophilin-like protein 8

3

1

High-throughput

0.667

High

1240355

DHB11
Estradiol 17-beta-dehydrogenase 11

3

1

High-throughput

0.653

High

310104

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

3

2

Small-scale

0.646

High

350660

RASK
GTPase KRas

3

5

High-throughput

0.640

High

352718

TNFA
Tumor necrosis factor

3

0

High-throughput

0.638

High

430727

CD3E
T-cell surface glycoprotein CD3 epsilon chain

3

0

High-throughput

0.638

High

623018

EDNRB
Endothelin receptor type B

2

4

High-throughput

0.628

High

1167706

SG1D4
Secretoglobin family 1D member 4

2

2

High-throughput

0.628

High

1328238

LMA2L
VIP36-like protein

2

2

High-throughput

0.628

High

545059

AMPN
Aminopeptidase N

1

6

High-throughput

0.618

High

1334826

SIAE
Sialate O-acetylesterase

2

1

High-throughput

0.611

High

426884

ASGR2
Asialoglycoprotein receptor 2

2

1

High-throughput

0.606

High

646337

STOM
Stomatin

2

3

High-throughput

0.606

High

945758

NGAL
Neutrophil gelatinase-associated lipocalin

2

1

High-throughput

0.606

High

1346065

S39A9
Zinc transporter ZIP9

2

1

High-throughput

0.606

High

1355875

UBQL1
Ubiquilin-1

2

1

High-throughput

0.606

High

1012547

TM267
Transmembrane protein 267

2

0

High-throughput

0.602

High

1204361

DYR2
Dihydrofolate reductase 2, mitochondrial

2

0

High-throughput

0.585

High

1303072

GPHA2
Glycoprotein hormone alpha-2

2

0

High-throughput

0.585

High

206137

TGON2
Trans-Golgi network integral membrane protein 2

2

2

High-throughput

0.584

High

348991

RASN
GTPase NRas

2

5

High-throughput

0.584

High

349715

RASH
GTPase HRas

2

3

High-throughput

0.584

High

592052

RAB4A
Ras-related protein Rab-4A

2

3

High-throughput

0.584

High

592564

RAB5A
Ras-related protein Rab-5A

2

2

High-throughput

0.584

High

845797

RAB9A
Ras-related protein Rab-9A

2

4

High-throughput

0.584

High

914437

RB11A
Ras-related protein Rab-11A

2

2

High-throughput

0.584

High

916055

RHOB
Rho-related GTP-binding protein RhoB

2

9

High-throughput

0.584

High

1344598

FBX6
F-box only protein 6

2

6

High-throughput

0.584

High

886956

T2R19
Taste receptor type 2 member 19

2

0

High-throughput

0.580

High

942578

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.580

High

1037768

AQP6
Aquaporin-6

2

0

High-throughput

0.580

High

1192438

S35E3
Solute carrier family 35 member E3

2

0

High-throughput

0.580

High

1203125

UN93A
Protein unc-93 homolog A

2

0

High-throughput

0.580

High

1233995

EMC5
ER membrane protein complex subunit 5

2

0

High-throughput

0.580

High

1251301

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.580

High

1256215

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.580

High

1262505

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.580

High

1296526

F210B
Protein FAM210B, mitochondrial

2

0

High-throughput

0.580

High

1298183

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.580

High

1355870

GGT7
Glutathione hydrolase 7

2

0

High-throughput

0.580

High

981774

REL
Proto-oncogene c-Rel

1

1

High-throughput

0.573

High

370659

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

328185

SG1D1
Secretoglobin family 1D member 1

1

2

High-throughput

0.536

High

328410

S1PR4
Sphingosine 1-phosphate receptor 4

1

3

High-throughput

0.536

High

344835

CYTC
Cystatin-C

1

1

High-throughput

0.536

High

354904

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

8

High-throughput

0.536

High

449378

LEG1
Galectin-1

1

5

High-throughput

0.536

High

656981

5HT1B
5-hydroxytryptamine receptor 1B

1

1

High-throughput

0.536

High

946073

DLK1
Protein delta homolog 1

1

2

High-throughput

0.536

High

1107987

LEG9B
Galectin-9B

1

5

High-throughput

0.536

High

1139008

GP107
Protein GPR107

1

1

High-throughput

0.536

High

1266058

AQP3
Aquaporin-3

1

1

High-throughput

0.536

High

1304434

DNJC2
DnaJ homolog subfamily C member 2

1

4

High-throughput

0.536

High

1336435

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.536

High

1345030

RNC
Ribonuclease 3

1

1

High-throughput

0.536

High

1354275

DNJB9
DnaJ homolog subfamily B member 9

1

6

High-throughput

0.536

High

1355871

FBX2
F-box only protein 2

1

6

High-throughput

0.536

High

1355877

HYOU1
Hypoxia up-regulated protein 1

1

3

High-throughput

0.536

High

1355878

ST14
Suppressor of tumorigenicity 14 protein

1

3

High-throughput

0.536

High

178036

TMPS2
Transmembrane protease serine 2

1

3

High-throughput

0.515

High

364472

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.515

High

1198217

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.515

High

1345086

TMPS4
Transmembrane protease serine 4

1

3

High-throughput

0.515

High

182051

GPR42
G-protein coupled receptor 42

1

8

High-throughput

0.515

High

64074

AQ12B
Aquaporin-12B

1

0

High-throughput

0.513

High

134756

CCL22
C-C motif chemokine 22

1

0

High-throughput

0.513

High

321362

STR3N
STARD3 N-terminal-like protein

1

0

High-throughput

0.513

High

351200

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.513

High

514499

PSPC
Surfactant protein C

1

0

High-throughput

0.513

High

616646

GLRA2
Glycine receptor subunit alpha-2

1

0

High-throughput

0.513

High

847955

CP2J2
Cytochrome P450 2J2

1

0

High-throughput

0.513

High

1037565

PNOC
Prepronociceptin [Cleaved into: Nocistatin; Nociceptin

1

0

High-throughput

0.513

High

1092780

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

1167769

PNCB
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.513

High

1190901

TAFA5
Chemokine-like protein TAFA-5

1

0

High-throughput

0.513

High

1260164

TM263
Transmembrane protein 263

1

0

High-throughput

0.513

High

1286980

GCC1
GRIP and coiled-coil domain-containing protein 1

1

0

High-throughput

0.513

High

1349571

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.513

High

648919

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.493

High

161165

CLGN
Calmegin

1

3

High-throughput

0.489

High

335573

NB5R3
NADH-cytochrome b5 reductase 3

1

2

High-throughput

0.481

High

1355879

FHOD1
FH1/FH2 domain-containing protein 1

1

1

Small-scale

0.481

High

344387

ANGT
Angiotensinogen

1

0

Small-scale

0.480

High

120702

RHOD
Rho-related GTP-binding protein RhoD

1

12

High-throughput

0.479

High

169660

BET1
BET1 homolog

1

1

High-throughput

0.479

High

178851

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

213051

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

318243

DIRA3
GTP-binding protein Di-Ras3

1

1

High-throughput

0.479

High

391244

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

434063

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

436562

RHOC
Rho-related GTP-binding protein RhoC

1

7

High-throughput

0.479

High

507300

LAMP1
Lysosome-associated membrane glycoprotein 1

1

2

High-throughput

0.479

High

526089

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

527870

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

545689

RAC2
Ras-related C3 botulinum toxin substrate 2

1

7

High-throughput

0.479

High

564727

RHOQ
Rho-related GTP-binding protein RhoQ

1

9

High-throughput

0.479

High

567319

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

591711

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.479

High

815047

LEG7
Galectin-7

1

5

High-throughput

0.479

High

825591

LMAN1
Protein ERGIC-53

1

2

High-throughput

0.479

High

844786

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.479

High

845333

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.479

High

852668

RND2
Rho-related GTP-binding protein RhoN

1

12

High-throughput

0.479

High

884611

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.479

High

890501

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

892669

RAC3
Ras-related C3 botulinum toxin substrate 3

1

8

High-throughput

0.479

High

894566

CDC42
Cell division control protein 42 homolog

1

9

High-throughput

0.479

High

895314

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.479

High

901030

RHOA
Transforming protein RhoA

1

8

High-throughput

0.479

High

913170

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

925713

RAC1
Ras-related C3 botulinum toxin substrate 1

1

8

High-throughput

0.479

High

951445

RHOG
Rho-related GTP-binding protein RhoG

1

7

High-throughput

0.479

High

965887

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

975099

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

1017842

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

1044242

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

2

High-throughput

0.479

High

1070444

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.479

High

1076807

RHOH
Rho-related GTP-binding protein RhoH

1

9

High-throughput

0.479

High

1084231

OCLN
Occludin

1

1

High-throughput

0.479

High

1087996

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

1

High-throughput

0.479

High

1146938

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1172175

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1183599

RHOU
Rho-related GTP-binding protein RhoU

1

11

High-throughput

0.479

High

1230418

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.479

High

1269246

RND1
Rho-related GTP-binding protein Rho6

1

13

High-throughput

0.479

High

1284152

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.479

High

1296113

DNJC1
DnaJ homolog subfamily C member 1

1

9

High-throughput

0.479

High

1330431

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

1330977

RHOJ
Rho-related GTP-binding protein RhoJ

1

9

High-throughput

0.479

High

1335380

RHOF
Rho-related GTP-binding protein RhoF

1

11

High-throughput

0.479

High

1346084

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

1350522

ANFY1
Rabankyrin-5

1

2

High-throughput

0.479

High

1354777

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1355873

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

1355874

MYO6
Unconventional myosin-VI

1

2

High-throughput

0.479

High

1355876

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

516169

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.460

High

673009

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.460

High

1060736

NTCP
Hepatic sodium/bile acid cotransporter

1

0

High-throughput

0.460

High

146063

CLD4
Claudin-4

1

0

Small-scale

0.458

High

164029

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

168071

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

305673

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

670272

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

795332

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

926046

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.458

High

967502

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1148855

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1152171

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1188437

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1303625

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1333615

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1346204

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

1348611

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

1349716

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1355872

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.458

High

602293

CD9
CD9 antigen

1

3

High-throughput

0.445

High

1355880

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

1

High-throughput

0.439

High

721724

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1328886

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.437

High

1329319

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.437

High

302617

CE152
Centrosomal protein of 152 kDa

1

0

High-throughput

0.426

High

1233253

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

1281125

FATE1
Fetal and adult testis-expressed transcript protein

3

0

High-throughput

0.352

High

1265358

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

0

High-throughput

0.328

High

1120705

NACHO
Novel acetylcholine receptor chaperone

2

0

High-throughput

0.316

High

1305541

CGRF1
Cell growth regulator with RING finger domain protein 1

2

0

High-throughput

0.316

High

1332308

REEP4
Receptor expression-enhancing protein 4

2

0

High-throughput

0.316

High

551309

ITF2
Transcription factor 4

1

0

High-throughput

0.299

High

1125848

NMS
Neuromedin-S

1

0

High-throughput

0.279

Low

1190578

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

1193276

B3GN8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

1

0

High-throughput

0.279

Low

1254678

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1270287

TF2H4
General transcription factor IIH subunit 4

1

0

High-throughput

0.279

Low

1031808

BIK
Bcl-2-interacting killer

1

0

High-throughput

0.251

Low

132628

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

1203894

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1283091

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024