Protein: I27L1
Interferon alpha-inducible protein 27-like protein 1 (Interferon-stimulated gene 12c protein) (ISG12(c)) (ISG12C)

Gene: I27L1, IFI27L1
Organism: Homo sapiens
Interactions: 64
UniProt ID: Q96BM0

Gene Ontology (top 5):
GO:0006915 - apoptotic process
GO:0031966 - mitochondrial membrane
GO:0060090 - molecular adaptor activity
GO:0097193 - intrinsic apoptotic signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1384728

SLTM
SAFB-like transcription modulator

1

2

High-throughput

0.536

High

238933

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

0

High-throughput

0.513

High

1121720

SAFB2
Scaffold attachment factor B2

1

2

High-throughput

0.489

High

1148456

SAFB1
Scaffold attachment factor B1

1

2

High-throughput

0.489

High

1212014

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

1

High-throughput

0.489

High

1327435

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

1

High-throughput

0.489

High

1360227

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

1

High-throughput

0.489

High

1384717

RMXL1
RNA binding motif protein, X-linked-like-1

1

1

High-throughput

0.489

High

1384721

DIDO1
Death-inducer obliterator 1

1

2

High-throughput

0.489

High

1384734

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.489

High

1238178

RHBD2
Rhomboid domain-containing protein 2

2

0

High-throughput

0.316

High

230557

KIF1C
Kinesin-like protein KIF1C

1

0

High-throughput

0.279

Low

280761

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.279

Low

321867

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

0

High-throughput

0.279

Low

569130

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.279

Low

675617

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.279

Low

875748

PRC2A
Protein PRRC2A

1

0

High-throughput

0.279

Low

889170

RBM25
RNA-binding protein 25

1

0

High-throughput

0.279

Low

928513

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.279

Low

935589

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.279

Low

940163

RRP1
Ribosomal RNA processing protein 1 homolog A

1

0

High-throughput

0.279

Low

1086801

BPTF
Nucleosome-remodeling factor subunit BPTF

1

0

High-throughput

0.279

Low

1088279

SFSWA
Splicing factor, suppressor of white-apricot homolog

1

0

High-throughput

0.279

Low

1095160

RED
Protein Red

1

0

High-throughput

0.279

Low

1111175

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

1124388

ELOA1
Elongin-A

1

0

High-throughput

0.279

Low

1193659

MAP9
Microtubule-associated protein 9

1

0

High-throughput

0.279

Low

1207418

HABP4
Intracellular hyaluronan-binding protein 4

1

0

High-throughput

0.279

Low

1208793

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

0

High-throughput

0.279

Low

1217828

PR38B
Pre-mRNA-splicing factor 38B

1

0

High-throughput

0.279

Low

1256710

NKAP1
Uncharacterized protein NKAPD1

1

0

High-throughput

0.279

Low

1259006

CENPU
Centromere protein U

1

0

High-throughput

0.279

Low

1270762

DDX46
Probable ATP-dependent RNA helicase DDX46

1

0

High-throughput

0.279

Low

1272108

RSRC2
Arginine/serine-rich coiled-coil protein 2

1

0

High-throughput

0.279

Low

1288220

LYRIC
Protein LYRIC

1

0

High-throughput

0.279

Low

1332831

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.279

Low

1336268

LS14A
Protein LSM14 homolog A

1

0

High-throughput

0.279

Low

1336747

RB15B
Putative RNA-binding protein 15B

1

0

High-throughput

0.279

Low

1346554

RP9
Retinitis pigmentosa 9 protein

1

0

High-throughput

0.279

Low

1346880

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.279

Low

1357078

CATIN
Splicing factor Cactin

1

0

High-throughput

0.279

Low

1358171

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.279

Low

1384718

RRP36
Ribosomal RNA processing protein 36 homolog

1

0

High-throughput

0.279

Low

1384719

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.279

Low

1384720

SCAFB
Protein SCAF11

1

0

High-throughput

0.279

Low

1384722

DCNL5
DCN1-like protein 5

1

0

High-throughput

0.279

Low

1384723

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.279

Low

1384724

ESF1
ESF1 homolog

1

0

High-throughput

0.279

Low

1384725

NCOA5
Nuclear receptor coactivator 5

1

0

High-throughput

0.279

Low

1384726

DCA13
DDB1- and CUL4-associated factor 13

1

0

High-throughput

0.279

Low

1384727

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.279

Low

1384729

CWC25
Pre-mRNA-splicing factor CWC25 homolog

1

0

High-throughput

0.279

Low

1384730

CDK12
Cyclin-dependent kinase 12

1

0

High-throughput

0.279

Low

1384731

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.279

Low

1384732

TAP26
Thyroid transcription factor 1-associated protein 26

1

0

High-throughput

0.279

Low

1384733

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.279

Low

1384735

ZO2
Tight junction protein 2

1

0

High-throughput

0.279

Low

1384736

DACH1
Dachshund homolog 1

1

0

High-throughput

0.279

Low

1384737

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

0

High-throughput

0.279

Low

1384738

WBP11
WW domain-binding protein 11

1

0

High-throughput

0.279

Low

1384739

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.279

Low

1384740

PAXB1
PAX3- and PAX7-binding protein 1

1

0

High-throughput

0.279

Low

1384741

ORC6
Origin recognition complex subunit 6

1

0

High-throughput

0.279

Low

1384742

5MP1
eIF5-mimic protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025