Protein: CMBL
Carboxymethylenebutenolidase homolog (EC 3.1.-.-)

Gene: CMBL
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q96DG6

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006805 - xenobiotic metabolic process
GO:0016787 - hydrolase activity
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

791623

SYUA
Alpha-synuclein

2

0

High-throughput

0.585

High

180893

TIF1A
Transcription intermediary factor 1-alpha

1

1

High-throughput

0.536

High

1387452

TPPC4
Trafficking protein particle complex subunit 4

1

1

High-throughput

0.536

High

1387458

TPPC1
Trafficking protein particle complex subunit 1

1

1

High-throughput

0.536

High

63867

TPC13
Trafficking protein particle complex subunit 13

1

0

High-throughput

0.513

High

591779

H2AX
Histone H2AX

1

0

High-throughput

0.513

High

914061

SPSY
Spermine synthase

1

0

High-throughput

0.513

High

1162732

QPCT
Glutaminyl-peptide cyclotransferase

1

0

High-throughput

0.513

High

1276035

TPC11
Trafficking protein particle complex subunit 11

1

0

High-throughput

0.513

High

1358524

TPC12
Trafficking protein particle complex subunit 12

1

0

High-throughput

0.513

High

1387436

KI20B
Kinesin-like protein KIF20B

1

0

High-throughput

0.513

High

1387451

TPC2L
Trafficking protein particle complex subunit 2-like protein

1

0

High-throughput

0.513

High

1387453

ST38L
Serine/threonine-protein kinase 38-like

1

0

High-throughput

0.513

High

1387454

TPPC8
Trafficking protein particle complex subunit 8

1

0

High-throughput

0.513

High

335894

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.493

High

728965

PUR9
Bifunctional purine biosynthesis protein ATIC

1

0

High-throughput

0.493

High

831220

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

882543

ARRB1
Beta-arrestin-1

1

0

High-throughput

0.493

High

903231

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

0

High-throughput

0.493

High

1112950

CUL2
Cullin-2

1

0

High-throughput

0.493

High

1124287

IF4A2
Eukaryotic initiation factor 4A-II

1

0

High-throughput

0.493

High

1387434

NP1L5
Nucleosome assembly protein 1-like 5

1

2

High-throughput

0.489

High

1387450

TSYL4
Testis-specific Y-encoded-like protein 4

1

2

High-throughput

0.489

High

242543

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

321112

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.458

High

347863

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

401277

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

520272

ANDR
Androgen receptor

1

0

High-throughput

0.458

High

900083

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.458

High

930011

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

957471

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

970899

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1138498

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1151614

TRIP6
Thyroid receptor-interacting protein 6

1

0

High-throughput

0.458

High

1194270

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

1197538

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.458

High

1229620

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1288557

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

1334753

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1387438

CRBN
Protein cereblon

1

0

Small-scale

0.458

High

1387441

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1387444

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

High-throughput

0.458

High

1387446

SMYD2
N-lysine methyltransferase SMYD2

1

0

High-throughput

0.458

High

1387448

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

988180

TRA2B
Transformer-2 protein homolog beta

1

1

High-throughput

0.437

High

1387447

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.437

High

449771

H2B1J
Histone H2B type 1-J

1

0

High-throughput

0.426

High

999396

HBB
Hemoglobin subunit beta

1

0

High-throughput

0.426

High

1039325

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.426

High

1092616

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.426

High

1228770

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

0

High-throughput

0.426

High

1258300

MOB2
MOB kinase activator 2

1

0

High-throughput

0.426

High

1387437

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

0

High-throughput

0.426

High

1387440

INP5K
Inositol polyphosphate 5-phosphatase K

1

0

High-throughput

0.426

High

1387443

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.426

High

1387445

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.426

High

936832

NP1L1
Nucleosome assembly protein 1-like 1

1

2

High-throughput

0.407

High

1111833

TRA2A
Transformer-2 protein homolog alpha

1

1

High-throughput

0.407

High

1387439

NP1L4
Nucleosome assembly protein 1-like 4

1

3

High-throughput

0.407

High

282287

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.279

Low

886552

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.279

Low

1387433

ZN514
Zinc finger protein 514

1

0

High-throughput

0.279

Low

1387457

PPME1
Protein phosphatase methylesterase 1

1

0

High-throughput

0.279

Low

257489

PAGE4
P antigen family member 4

1

0

High-throughput

0.249

Low

294155

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

325043

HEXI1
Protein HEXIM1

1

0

High-throughput

0.249

Low

353488

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

589378

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

643021

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.249

Low

696179

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768859

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1061085

SRSF1
Serine/arginine-rich splicing factor 1

1

0

High-throughput

0.249

Low

1205467

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

1255003

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1271783

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.249

Low

1364200

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.249

Low

1387432

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1387442

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1387449

PUF60
Poly(U)-binding-splicing factor PUF60

1

0

High-throughput

0.249

Low

1387455

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

270041

XYLK
Glycosaminoglycan xylosylkinase

1

0

High-throughput

0.232

Low

923666

RCAN1
Calcipressin-1

1

0

High-throughput

0.232

Low

1352487

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.232

Low

1387435

F111A
Serine protease FAM111A

1

0

High-throughput

0.232

Low

1387456

NOP16
Nucleolar protein 16

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025