Protein: AGO3
Protein argonaute-3 (Argonaute3) (hAgo3) (EC 3.1.26.n2) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3)

Gene: AGO3
Organism: Homo sapiens
Interactions: 151
UniProt ID: Q9H9G7

Gene Ontology (top 5):
GO:0000794 - condensed nuclear chromosome
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0003725 - double-stranded RNA binding
GO:0003727 - single-stranded RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1334286

AGO2
Protein argonaute-2

5

12

High-throughput

0.919

High

1334275

AGO4
Protein argonaute-4

3

12

High-throughput

0.861

High

1334291

DICER
Endoribonuclease Dicer

3

20

Small-scale

0.847

High

1334288

AGO1
Protein argonaute-1

2

12

High-throughput

0.789

High

1242656

TNR6A
Trinucleotide repeat-containing gene 6A protein

8

19

Small-scale

0.750

High

1334290

TNR6B
Trinucleotide repeat-containing gene 6B protein

7

18

Small-scale

0.748

High

1334274

TNR6C
Trinucleotide repeat-containing gene 6C protein

4

20

Small-scale

0.696

High

1035002

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

4

16

High-throughput

0.694

High

432271

HS90A
Heat shock protein HSP 90-alpha

4

20

High-throughput

0.691

High

120036

AP3B1
AP-3 complex subunit beta-1

3

2

High-throughput

0.667

High

150269

AP3D1
AP-3 complex subunit delta-1

3

3

High-throughput

0.667

High

1115486

LONF3
LON peptidase N-terminal domain and RING finger protein 3

3

20

High-throughput

0.667

High

1217274

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

3

6

High-throughput

0.667

High

966647

OTUD4
OTU domain-containing protein 4

2

1

High-throughput

0.611

High

1267491

AP3S1
AP-3 complex subunit sigma-1

3

2

High-throughput

0.609

High

178273

IPO8
Importin-8

1

5

High-throughput

0.586

High

1334276

MOG1
Ran guanine nucleotide release factor

2

0

High-throughput

0.585

High

858668

PPP5
Serine/threonine-protein phosphatase 5

1

6

High-throughput

0.554

High

1123440

H90B4
Putative heat shock protein HSP 90-beta 4

2

20

High-throughput

0.552

High

1123504

HS905
Putative heat shock protein HSP 90-alpha A5

2

20

High-throughput

0.552

High

529735

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.541

High

153793

ANM5
Protein arginine N-methyltransferase 5

1

3

High-throughput

0.536

High

381305

TBB4A
Tubulin beta-4A chain

1

7

High-throughput

0.536

High

428441

TBB5
Tubulin beta chain

1

7

High-throughput

0.536

High

438537

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.536

High

506060

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

4

High-throughput

0.536

High

585070

RO52
E3 ubiquitin-protein ligase TRIM21

1

3

High-throughput

0.536

High

598327

FLNA
Filamin-A

1

1

High-throughput

0.536

High

618714

IF4B
Eukaryotic translation initiation factor 4B

1

14

High-throughput

0.536

High

681603

DNJA1
DnaJ homolog subfamily A member 1

1

8

High-throughput

0.536

High

725025

MYH9
Myosin-9

1

5

High-throughput

0.536

High

725563

COPB2
Coatomer subunit beta'

1

4

High-throughput

0.536

High

751835

GRP75
Stress-70 protein, mitochondrial

1

9

High-throughput

0.536

High

763099

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

2

High-throughput

0.536

High

826893

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.536

High

867469

ICLN
Methylosome subunit pICln

1

1

High-throughput

0.536

High

932872

EF1A1
Elongation factor 1-alpha 1

1

3

High-throughput

0.536

High

933979

TBB4B
Tubulin beta-4B chain

1

7

High-throughput

0.536

High

963420

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

3

High-throughput

0.536

High

1042564

CUL3
Cullin-3

1

6

High-throughput

0.536

High

1045524

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

3

High-throughput

0.536

High

1046585

TBB2A
Tubulin beta-2A chain

1

7

High-throughput

0.536

High

1069514

TEBP
Prostaglandin E synthase 3

1

10

High-throughput

0.536

High

1077960

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

1

High-throughput

0.536

High

1175187

TBA1A
Tubulin alpha-1A chain

1

6

High-throughput

0.536

High

1202127

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.536

High

1263022

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

2

High-throughput

0.536

High

1263541

PSPC1
Paraspeckle component 1

1

13

High-throughput

0.536

High

1274052

CUL5
Cullin-5

1

6

High-throughput

0.536

High

1283461

SPSB4
SPRY domain-containing SOCS box protein 4

1

6

High-throughput

0.536

High

1305269

PHB2
Prohibitin-2

1

4

High-throughput

0.536

High

1309285

MEP50
Methylosome protein WDR77

1

6

High-throughput

0.536

High

1334280

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

1

High-throughput

0.536

High

1334292

RUVB2
RuvB-like 2

1

3

High-throughput

0.536

High

1334297

SF3B6
Splicing factor 3B subunit 6

1

9

High-throughput

0.536

High

173311

S22A2
Solute carrier family 22 member 2

1

0

High-throughput

0.518

High

618304

BDNF
Brain-derived neurotrophic factor

1

0

High-throughput

0.518

High

1237959

VA0D2
V-type proton ATPase subunit d 2

1

0

High-throughput

0.518

High

149746

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

1069653

STK38
Serine/threonine-protein kinase 38

1

0

High-throughput

0.513

High

1204206

CIR1
Corepressor interacting with RBPJ 1

1

0

High-throughput

0.513

High

1334284

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.513

High

1334287

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

1334293

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.513

High

1334298

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

1334300

SPIN1
Spindlin-1

1

0

High-throughput

0.513

High

1135336

ATD3B
ATPase family AAA domain-containing protein 3B

1

3

High-throughput

0.489

High

63211

WTIP
Wilms tumor protein 1-interacting protein

1

7

Small-scale

0.479

High

163297

XPO1
Exportin-1

1

2

High-throughput

0.479

High

166314

GRRE1
Granule associated Rac and RHOG effector protein 1

1

2

High-throughput

0.479

High

170478

TIF1A
Transcription intermediary factor 1-alpha

1

12

Small-scale

0.479

High

182913

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

200905

CTIF
CBP80/20-dependent translation initiation factor

1

4

High-throughput

0.479

High

257701

ANR17
Ankyrin repeat domain-containing protein 17

1

3

High-throughput

0.479

High

309075

KI20A
Kinesin-like protein KIF20A

1

9

High-throughput

0.479

High

323159

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

16

High-throughput

0.479

High

347920

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

374893

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

379879

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.479

High

476398

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

6

High-throughput

0.479

High

498353

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

1

High-throughput

0.479

High

516695

PABP1
Polyadenylate-binding protein 1

1

10

High-throughput

0.479

High

615844

GCSP
Glycine dehydrogenase

1

2

High-throughput

0.479

High

640626

DDX6
Probable ATP-dependent RNA helicase DDX6

1

20

High-throughput

0.479

High

644327

TTP
mRNA decay activator protein ZFP36

1

5

High-throughput

0.479

High

647963

MARK3
MAP/microtubule affinity-regulating kinase 3

1

11

High-throughput

0.479

High

652283

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

668428

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

18

High-throughput

0.479

High

721475

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

749862

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.479

High

821041

PRC2A
Protein PRRC2A

1

5

High-throughput

0.479

High

844248

FXR2
RNA-binding protein FXR2

1

17

High-throughput

0.479

High

962377

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

5

High-throughput

0.479

High

969999

KIF23
Kinesin-like protein KIF23

1

5

High-throughput

0.479

High

1030489

G3BP1
Ras GTPase-activating protein-binding protein 1

1

7

High-throughput

0.479

High

1048232

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

15

Small-scale

0.479

High

1049892

UBP2L
Ubiquitin-associated protein 2-like

1

2

High-throughput

0.479

High

1056749

PUM1
Pumilio homolog 1

1

4

High-throughput

0.479

High

1061623

CUL7
Cullin-7

1

3

High-throughput

0.479

High

1066718

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1075637

TRBP2
RISC-loading complex subunit TARBP2

1

15

High-throughput

0.479

High

1089566

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

17

High-throughput

0.479

High

1136298

RC3H1
Roquin-1

1

4

High-throughput

0.479

High

1159007

EDC4
Enhancer of mRNA-decapping protein 4

1

2

Small-scale

0.479

High

1159094

CEP85
Centrosomal protein of 85 kDa

1

6

High-throughput

0.479

High

1168839

MEX3B
RNA-binding protein MEX3B

1

6

High-throughput

0.479

High

1171758

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1183124

MARK2
Serine/threonine-protein kinase MARK2

1

11

High-throughput

0.479

High

1187785

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

4

High-throughput

0.479

High

1192379

YTHD3
YTH domain-containing family protein 3

1

9

High-throughput

0.479

High

1198390

PATL1
Protein PAT1 homolog 1

1

6

High-throughput

0.479

High

1219242

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

20

High-throughput

0.479

High

1242132

LS14A
Protein LSM14 homolog A

1

5

High-throughput

0.479

High

1262820

PHIP
PH-interacting protein

1

1

High-throughput

0.479

High

1267871

CNOT9
CCR4-NOT transcription complex subunit 9

1

2

High-throughput

0.479

High

1271850

ATOH1
Transcription factor ATOH1

1

2

Small-scale

0.479

High

1272103

CELF1
CUGBP Elav-like family member 1

1

13

High-throughput

0.479

High

1272483

DAZL
Deleted in azoospermia-like

1

18

High-throughput

0.479

High

1291703

BICD1
Protein bicaudal D homolog 1

1

6

High-throughput

0.479

High

1294256

FUBP3
Far upstream element-binding protein 3

1

17

High-throughput

0.479

High

1297128

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

8

High-throughput

0.479

High

1305693

ATX2
Ataxin-2

1

3

High-throughput

0.479

High

1310149

LZTS2
Leucine zipper putative tumor suppressor 2

1

6

High-throughput

0.479

High

1317021

YTHD1
YTH domain-containing family protein 1

1

9

High-throughput

0.479

High

1317740

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

11

High-throughput

0.479

High

1326987

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

3

High-throughput

0.479

High

1334273

MOV10
Helicase MOV-10

1

10

High-throughput

0.479

High

1334277

DCP1A
mRNA-decapping enzyme 1A

1

2

High-throughput

0.479

High

1334278

4ET
Eukaryotic translation initiation factor 4E transporter

1

2

High-throughput

0.479

High

1334279

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

4

High-throughput

0.479

High

1334281

CNOT2
CCR4-NOT transcription complex subunit 2

1

4

High-throughput

0.479

High

1334282

MARK1
Serine/threonine-protein kinase MARK1

1

11

High-throughput

0.479

High

1334283

LIMD1
LIM domain-containing protein 1

1

7

Small-scale

0.479

High

1334285

CNOT7
CCR4-NOT transcription complex subunit 7

1

6

High-throughput

0.479

High

1334289

ZN346
Zinc finger protein 346

1

1

High-throughput

0.479

High

1334294

NINL
Ninein-like protein

1

5

High-throughput

0.479

High

1334295

R3HD2
R3H domain-containing protein 2

1

5

High-throughput

0.479

High

1334299

YTHD2
YTH domain-containing family protein 2

1

9

High-throughput

0.479

High

553744

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

267450

ECI2
Enoyl-CoA delta isomerase 2

1

2

High-throughput

0.445

High

882577

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

6

High-throughput

0.445

High

892039

ACTB
Actin, cytoplasmic 1

1

2

High-throughput

0.445

High

958129

RBM10
RNA-binding protein 10

1

14

High-throughput

0.445

High

959311

S25A3
Solute carrier family 25 member 3

1

12

High-throughput

0.445

High

1022601

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

2

High-throughput

0.445

High

1123461

H90B3
Putative heat shock protein HSP 90-beta-3

1

20

High-throughput

0.445

High

1330628

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

6

High-throughput

0.445

High

1072827

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

2

High-throughput

0.437

High

1334296

AP3M1
AP-3 complex subunit mu-1

3

0

High-throughput

0.347

High

845969

ATP4B
Potassium-transporting ATPase subunit beta

1

0

High-throughput

0.282

High

434671

TSP1
Thrombospondin-1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024