Protein: HJURP
Holliday junction recognition protein (14-3-3-associated AKT substrate) (Fetal liver-expressing gene 1 protein) (Up-regulated in lung cancer 9)

Gene: HJURP
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q8NCD3

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

883615

CENPA
Histone H3-like centromeric protein A

13

0

Small-scale

0.937

High

980003

H4
Histone H4

4

0

Small-scale

0.853

High

1066403

RBBP4
Histone-binding protein RBBP4

5

1

Small-scale

0.720

High

447232

NPM
Nucleophosmin

4

1

Small-scale

0.699

High

1335462

MS18A
Protein Mis18-alpha

4

0

Small-scale

0.667

High

217156

MS18B
Protein Mis18-beta

2

0

Small-scale

0.609

High

1335441

HJURP
Holliday junction recognition protein

1

0

Small-scale

0.561

High

288706

NPM3
Nucleoplasmin-3

1

1

High-throughput

0.536

High

457560

TBB5
Tubulin beta chain

1

1

High-throughput

0.536

High

1158925

RBBP7
Histone-binding protein RBBP7

1

1

Small-scale

0.536

High

1335463

KLH14
Kelch-like protein 14

1

1

High-throughput

0.536

High

1335472

RUVB2
RuvB-like 2

1

1

Small-scale

0.536

High

1335473

RUVB1
RuvB-like 1

1

1

Small-scale

0.536

High

258990

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.513

High

317347

ACL6B
Actin-like protein 6B

1

0

High-throughput

0.513

High

347178

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

586788

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

686281

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

809731

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

975811

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

1061060

SRSF1
Serine/arginine-rich splicing factor 1

1

0

High-throughput

0.513

High

1144080

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1147963

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.513

High

1335451

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

1335456

RBM4B
RNA-binding protein 4B

1

0

High-throughput

0.513

High

1335461

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.513

High

1335469

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

1108615

TBB3
Tubulin beta-3 chain

1

1

High-throughput

0.489

High

1323912

KLH34
Kelch-like protein 34

1

1

High-throughput

0.489

High

443444

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

210314

PHF1
PHD finger protein 1

1

1

High-throughput

0.479

High

285370

EED
Polycomb protein EED

1

1

High-throughput

0.479

High

316918

MTA2
Metastasis-associated protein MTA2

1

2

High-throughput

0.479

High

352190

MBD3
Methyl-CpG-binding domain protein 3

1

1

High-throughput

0.479

High

691255

1433T
14-3-3 protein theta

1

5

High-throughput

0.479

High

703353

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

1

High-throughput

0.479

High

730061

1433B
14-3-3 protein beta/alpha

1

5

High-throughput

0.479

High

966626

1433G
14-3-3 protein gamma

1

5

High-throughput

0.479

High

990506

1433Z
14-3-3 protein zeta/delta

1

5

High-throughput

0.479

High

1049568

1433F
14-3-3 protein eta

1

5

High-throughput

0.479

High

1088458

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

1102602

MTA1
Metastasis-associated protein MTA1

1

2

High-throughput

0.479

High

1295265

P66A
Transcriptional repressor p66-alpha

1

1

High-throughput

0.479

High

1335443

P66B
Transcriptional repressor p66-beta

1

1

High-throughput

0.479

High

1335457

MTA3
Metastasis-associated protein MTA3

1

2

High-throughput

0.479

High

1335464

MBD2
Methyl-CpG-binding domain protein 2

1

1

High-throughput

0.479

High

1335466

HMGX4
HMG domain-containing protein 4

1

1

High-throughput

0.479

High

1335475

MTF2
Metal-response element-binding transcription factor 2

1

1

High-throughput

0.479

High

155327

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.458

High

282275

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.458

High

332017

KAT7
Histone acetyltransferase KAT7

1

0

Small-scale

0.458

High

519528

MYBB
Myb-related protein B

1

0

High-throughput

0.458

High

695966

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

810227

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

872538

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

888194

MCM2
DNA replication licensing factor MCM2

1

0

Small-scale

0.458

High

971790

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

1004843

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1045534

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1086792

BPTF
Nucleosome-remodeling factor subunit BPTF

1

0

High-throughput

0.458

High

1140577

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1197995

LIN52
Protein lin-52 homolog

1

0

High-throughput

0.458

High

1216610

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.458

High

1240388

M18BP
Mis18-binding protein 1

1

0

Small-scale

0.458

High

1312672

BAP18
BPTF-associated chromatin complex component 1

1

0

High-throughput

0.458

High

1335444

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1335445

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.458

High

1335448

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.458

High

1335450

Z512B
Zinc finger protein 512B

1

0

High-throughput

0.458

High

1335452

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1335453

PWP2A
PWWP domain-containing protein 2A

1

0

High-throughput

0.458

High

1335454

PASK
PAS domain-containing serine/threonine-protein kinase

1

0

High-throughput

0.458

High

1335458

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1335459

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1335460

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1335467

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.458

High

1335468

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.458

High

1335471

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

0

High-throughput

0.458

High

1239880

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.426

High

142585

IMA3
Importin subunit alpha-3

1

0

High-throughput

0.391

High

1335447

LRC46
Leucine-rich repeat-containing protein 46

4

0

High-throughput

0.360

High

1241190

DUS1L
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like

2

0

High-throughput

0.318

High

1335474

WASC3
WASH complex subunit 3

2

0

High-throughput

0.313

High

1164471

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.282

High

848681

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.279

Low

1335446

HDA11
Histone deacetylase 11

1

0

High-throughput

0.279

Low

1335449

ZN333
Zinc finger protein 333

1

0

High-throughput

0.279

Low

1335455

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.279

Low

1335476

NGN3
Neurogenin-3

1

0

High-throughput

0.279

Low

1335477

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.279

Low

294039

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1208618

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

0

High-throughput

0.249

Low

1254686

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1276495

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1335442

ZN296
Zinc finger protein 296

1

0

High-throughput

0.249

Low

1335470

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

863516

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

0

High-throughput

0.238

Low

844834

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.232

Low

1335465

TRI10
Tripartite motif-containing protein 10

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025