Protein: CAF17
Iron-sulfur cluster assembly factor IBA57, mitochondrial (Iron-sulfur cluster assembly factor homolog)

Gene: CAF17, IBA57
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q5T440

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006783 - heme biosynthetic process
GO:0016226 - iron-sulfur cluster assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1212515

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

3

5

Small-scale

0.662

High

532648

CH60
60 kDa heat shock protein, mitochondrial

4

0

High-throughput

0.661

High

635327

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

3

0

High-throughput

0.634

High

953908

IF4A1
Eukaryotic initiation factor 4A-I

3

0

High-throughput

0.634

High

1212522

RRFM
Ribosome-recycling factor, mitochondrial

3

0

High-throughput

0.628

High

708978

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.602

High

1203440

OXLD1
Oxidoreductase-like domain-containing protein 1

2

0

High-throughput

0.585

High

1212533

HINT2
Adenosine 5'-monophosphoramidase HINT2

2

0

High-throughput

0.585

High

279787

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

1162362

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

1212532

TR61B
tRNA

2

0

High-throughput

0.547

High

1212531

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

5

High-throughput

0.536

High

1212518

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

281973

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.479

High

350892

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

1

High-throughput

0.479

High

471071

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

856282

IF2M
Translation initiation factor IF-2, mitochondrial

1

2

High-throughput

0.479

High

882713

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

1083634

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.479

High

1117753

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

1138298

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1212517

ECHD2
Enoyl-CoA hydratase domain-containing protein 2, mitochondrial

1

1

High-throughput

0.479

High

1212519

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

2

High-throughput

0.479

High

1212520

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

1212525

EFGM
Elongation factor G, mitochondrial

1

2

High-throughput

0.479

High

1212537

MTRFR
Mitochondrial translation release factor in rescue

1

1

High-throughput

0.479

High

1212539

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.479

High

1212549

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

1

High-throughput

0.479

High

1212551

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

1

High-throughput

0.479

High

66214

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

241926

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

519132

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

559982

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

786123

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

828801

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

841775

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

851912

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

927020

ATX3
Ataxin-3

1

0

Small-scale

0.458

High

1024066

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1048549

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1058065

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1087413

GRSF1
G-rich sequence factor 1

1

0

High-throughput

0.458

High

1090428

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1123311

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.458

High

1142565

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1207034

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1212509

MIC10
MICOS complex subunit MIC10

1

0

Small-scale

0.458

High

1212511

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1212516

NIT1
Deaminated glutathione amidase

1

0

High-throughput

0.458

High

1212521

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.458

High

1212523

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1212526

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

1212527

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1212528

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

1212530

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1212534

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1212535

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1212536

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1212540

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1212546

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1212548

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1212550

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1212554

KAD3
GTP:AMP phosphotransferase AK3, mitochondrial

1

0

High-throughput

0.458

High

1212556

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

1212538

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

430016

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

653367

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

777614

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

0

High-throughput

0.426

High

1212524

MCEE
Methylmalonyl-CoA epimerase, mitochondrial

1

0

High-throughput

0.426

High

1212543

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.426

High

1212553

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.426

High

1212557

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

0

High-throughput

0.426

High

1212512

T184A
Transmembrane protein 184A

2

0

High-throughput

0.328

High

1212514

RHG22
Rho GTPase-activating protein 22

2

0

High-throughput

0.328

High

1212544

LUC7L
Putative RNA-binding protein Luc7-like 1

2

0

High-throughput

0.318

High

946420

MTPN
Myotrophin

1

0

High-throughput

0.279

Low

1158815

CART

1

0

High-throughput

0.279

Low

1212529

SPXN
Spexin

1

0

High-throughput

0.279

Low

370204

CYTN
Cystatin-SN

1

0

Small-scale

0.249

Low

588877

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

630424

RAB3A
Ras-related protein Rab-3A

1

0

High-throughput

0.249

Low

695657

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

883260

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.249

Low

970630

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1096564

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.249

Low

1113321

CUL3
Cullin-3

1

0

High-throughput

0.249

Low

1137760

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.249

Low

1212510

OTUD1
OTU domain-containing protein 1

1

0

High-throughput

0.249

Low

1212513

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1212541

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3

1

0

High-throughput

0.249

Low

1212542

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.249

Low

1212545

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

0

Small-scale

0.249

Low

1212547

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1212552

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1212555

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025