Protein: IGJ
Immunoglobulin J chain (Joining chain of multimeric IgA and IgM)

Gene: IGJ, JCHAIN
Organism: Homo sapiens
Interactions: 81
UniProt ID: P01591

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0003094 - glomerular filtration
GO:0003823 - antigen binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

378670

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

3

0

High-throughput

0.816

High

378704

NPB
Neuropeptide B

2

0

High-throughput

0.602

High

378694

HBM
Hemoglobin subunit mu

2

1

High-throughput

0.574

High

141971

FCN1
Ficolin-1

1

1

High-throughput

0.536

High

210644

KLK10
Kallikrein-10

1

0

High-throughput

0.513

High

253265

JAK2
Tyrosine-protein kinase JAK2

1

0

High-throughput

0.513

High

378669

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

378676

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.513

High

378687

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.513

High

378702

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.513

High

378706

ITLN2
Intelectin-2

1

0

High-throughput

0.513

High

378710

HVCN1
Voltage-gated hydrogen channel 1

1

0

High-throughput

0.513

High

378712

SNF8
Vacuolar-sorting protein SNF8

1

0

High-throughput

0.513

High

378665

HBAT
Hemoglobin subunit theta-1

1

1

High-throughput

0.489

High

302298

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

High-throughput

0.458

High

378664

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

378666

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

229255

ANGL7
Angiopoietin-related protein 7

1

1

High-throughput

0.445

High

378686

OASL
2'-5'-oligoadenylate synthase-like protein

1

1

High-throughput

0.437

High

378667

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.426

High

378668

CRHBP
Corticotropin-releasing factor-binding protein

1

0

High-throughput

0.426

High

378677

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.426

High

378678

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.426

High

378682

STK4
Serine/threonine-protein kinase 4

1

0

High-throughput

0.426

High

378729

PRG3
Proteoglycan 3

1

0

High-throughput

0.426

High

378714

TM237
Transmembrane protein 237

3

0

High-throughput

0.347

High

225159

TRIA1
TP53-regulated inhibitor of apoptosis 1

2

0

High-throughput

0.328

High

318562

RHBT1
Rho-related BTB domain-containing protein 1

2

0

High-throughput

0.328

High

378679

TF2B
Transcription initiation factor IIB

2

0

High-throughput

0.328

High

378689

PKHG6
Pleckstrin homology domain-containing family G member 6

2

0

High-throughput

0.328

High

378692

ICE2
Little elongation complex subunit 2

2

0

High-throughput

0.328

High

378698

APCD1
Protein APCDD1

2

0

High-throughput

0.328

High

378700

FRMD1
FERM domain-containing protein 1

2

0

High-throughput

0.328

High

378701

ZN491
Zinc finger protein 491

2

0

High-throughput

0.328

High

378713

SNX27
Sorting nexin-27

2

0

High-throughput

0.328

High

378718

DDX31
ATP-dependent DNA helicase DDX31

2

0

High-throughput

0.328

High

378721

WDR6
tRNA

2

0

High-throughput

0.328

High

378722

ZCC17
Zinc finger CCHC domain-containing protein 17

2

0

High-throughput

0.328

High

378731

ORNT1
Mitochondrial ornithine transporter 1

2

0

High-throughput

0.328

High

67413

GOG8A
Golgin subfamily A member 8A

1

0

High-throughput

0.279

Low

133833

FOXN3
Forkhead box protein N3

1

0

High-throughput

0.279

Low

335215

CXB5
Gap junction beta-5 protein

1

0

High-throughput

0.279

Low

354007

CX001
Putative transmembrane protein CXorf1

1

0

High-throughput

0.279

Low

378673

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.279

Low

378674

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

0

High-throughput

0.279

Low

378681

TWF1
Twinfilin-1

1

0

High-throughput

0.279

Low

378683

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

378684

RUNX2
Runt-related transcription factor 2

1

0

High-throughput

0.279

Low

378685

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.279

Low

378690

T176B
Transmembrane protein 176B

1

0

High-throughput

0.279

Low

378691

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.279

Low

378695

SFXN4
Sideroflexin-4

1

0

High-throughput

0.279

Low

378696

PBIR3
PABIR family member 1

1

0

High-throughput

0.279

Low

378697

ELOA2
Elongin-A2

1

0

High-throughput

0.279

Low

378699

RIBC1
RIB43A-like with coiled-coils protein 1

1

0

High-throughput

0.279

Low

378703

AT11C
Phospholipid-transporting ATPase IG

1

0

High-throughput

0.279

Low

378705

O13C3
Olfactory receptor 13C3

1

0

High-throughput

0.279

Low

378707

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.279

Low

378709

PMEPA
Protein TMEPAI

1

0

High-throughput

0.279

Low

378711

DISP1
Protein dispatched homolog 1

1

0

High-throughput

0.279

Low

378715

USB1
U6 snRNA phosphodiesterase 1

1

0

High-throughput

0.279

Low

378717

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.279

Low

378719

COE2
Transcription factor COE2

1

0

High-throughput

0.279

Low

378720

CP343
Cytochrome P450 3A43

1

0

High-throughput

0.279

Low

378723

NOX4
NADPH oxidase 4

1

0

High-throughput

0.279

Low

378724

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

0

High-throughput

0.279

Low

378726

ARMX3
Armadillo repeat-containing X-linked protein 3

1

0

High-throughput

0.279

Low

378727

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.279

Low

378730

SF3B6
Splicing factor 3B subunit 6

1

0

High-throughput

0.279

Low

277227

PITX3
Pituitary homeobox 3

1

0

Small-scale

0.249

Low

378671

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.249

Low

378672

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

378675

EFNA3
Ephrin-A3

1

0

High-throughput

0.249

Low

378680

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.249

Low

378725

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.249

Low

378728

NINL
Ninein-like protein

1

0

High-throughput

0.249

Low

261046

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

378688

TR16L
Tripartite motif-containing protein 16-like protein

1

0

High-throughput

0.232

Low

378693

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

378708

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

0

High-throughput

0.232

Low

378716

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025