Protein: EXOC5
Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10)

Gene: EXOC5
Organism: Homo sapiens
Interactions: 159
UniProt ID: O00471

Gene Ontology (top 5):
GO:0000145 - exocyst
GO:0000281 - mitotic cytokinesis
GO:0001736 - establishment of planar polarity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

137259

EXOC4
Exocyst complex component 4

2

2

Small-scale

0.789

High

137254

EXOC6
Exocyst complex component 6

5

3

High-throughput

0.721

High

137157

EXOC3
Exocyst complex component 3

5

2

Small-scale

0.716

High

137248

EXOC8
Exocyst complex component 8

4

1

High-throughput

0.699

High

137295

EXC6B
Exocyst complex component 6B

4

3

High-throughput

0.698

High

137165

OAS1
2'-5'-oligoadenylate synthase 1

4

0

High-throughput

0.679

High

137180

RAB4A
Ras-related protein Rab-4A

3

5

High-throughput

0.675

High

137209

RAB4B
Ras-related protein Rab-4B

3

5

High-throughput

0.675

High

137210

RAB14
Ras-related protein Rab-14

3

5

High-throughput

0.675

High

137227

PTK6
Protein-tyrosine kinase 6

3

1

High-throughput

0.675

High

137279

EXOC1
Exocyst complex component 1

4

0

High-throughput

0.667

High

137220

DEUP1
Deuterosome assembly protein 1

3

0

High-throughput

0.646

High

137229

SETB1
Histone-lysine N-methyltransferase SETDB1

3

0

High-throughput

0.638

High

137261

DTBP1
Dysbindin

3

0

High-throughput

0.638

High

137275

DSN1
Kinetochore-associated protein DSN1 homolog

3

0

High-throughput

0.638

High

137158

SCN2B
Sodium channel regulatory subunit beta-2

4

1

High-throughput

0.630

High

137161

STX11
Syntaxin-11

2

1

High-throughput

0.628

High

137198

MAGA6
Melanoma-associated antigen 6

3

1

High-throughput

0.616

High

137148

TNPO2
Transportin-2

2

0

High-throughput

0.613

High

137187

IL1R2
Interleukin-1 receptor type 2

2

0

High-throughput

0.602

High

137296

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.602

High

137250

TXLNB
Beta-taxilin

2

0

High-throughput

0.601

High

137212

RB11A
Ras-related protein Rab-11A

2

3

High-throughput

0.584

High

137162

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

0

High-throughput

0.580

High

137262

THOC1
THO complex subunit 1

2

0

High-throughput

0.580

High

137280

IFT57
Intraflagellar transport protein 57 homolog

2

0

High-throughput

0.580

High

137168

GLPA
Glycophorin-A

2

0

High-throughput

0.576

High

137193

SYUA
Alpha-synuclein

2

0

High-throughput

0.575

High

137184

EDNRB
Endothelin receptor type B

2

2

High-throughput

0.574

High

137192

OPRM
Mu-type opioid receptor

2

1

High-throughput

0.574

High

137201

NPY2R
Neuropeptide Y receptor type 2

2

1

High-throughput

0.574

High

137267

BARD1
BRCA1-associated RING domain protein 1

1

1

High-throughput

0.573

High

137197

MAGA3
Melanoma-associated antigen 3

2

1

High-throughput

0.553

High

137211

ARF6
ADP-ribosylation factor 6

1

0

Small-scale

0.549

High

137153

GP182
G-protein coupled receptor 182

2

3

High-throughput

0.549

High

137214

TXN4A
Thioredoxin-like protein 4A

1

0

High-throughput

0.549

High

137237

C102B
Coiled-coil domain-containing protein 102B

1

0

High-throughput

0.549

High

137240

TT23L
Tetratricopeptide repeat protein 23-like

1

0

High-throughput

0.549

High

137265

FRMD6
FERM domain-containing protein 6

1

0

High-throughput

0.549

High

137291

ASC
Apoptosis-associated speck-like protein containing a CARD

1

0

High-throughput

0.549

High

137236

A16L1
Autophagy-related protein 16-1

2

0

High-throughput

0.547

High

137146

EXOC5
Exocyst complex component 5

1

3

High-throughput

0.541

High

137150

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

1

High-throughput

0.541

High

137284

ARP3B
Actin-related protein 3B

1

1

High-throughput

0.541

High

137208

RAB8A
Ras-related protein Rab-8A

1

1

High-throughput

0.536

High

137213

1433Z
14-3-3 protein zeta/delta

1

1

High-throughput

0.536

High

137230

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

High-throughput

0.536

High

137244

EX3L1
Exocyst complex component 3-like protein

1

2

High-throughput

0.536

High

137263

EXOC2
Exocyst complex component 2

1

2

High-throughput

0.536

High

137286

GGA1
ADP-ribosylation factor-binding protein GGA1

1

1

High-throughput

0.536

High

137293

EXOC7
Exocyst complex component 7

1

1

High-throughput

0.536

High

137179

CADH2
Cadherin-2

1

0

High-throughput

0.518

High

137218

ICA69
Islet cell autoantigen 1

1

0

High-throughput

0.518

High

137238

Q6FHV6
phosphopyruvate hydratase

1

1

High-throughput

0.515

High

137160

MTX2
Metaxin-2

1

0

High-throughput

0.513

High

137175

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

137199

NSF
Vesicle-fusing ATPase

1

0

High-throughput

0.513

High

137216

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

137247

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.513

High

137264

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

137266

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

137166

CRYAB
Alpha-crystallin B chain

1

0

High-throughput

0.493

High

137169

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.493

High

137183

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.493

High

137196

HD
Huntingtin

1

0

High-throughput

0.493

High

137242

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

137292

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

High-throughput

0.493

High

137200

GLR
Glucagon receptor

1

1

High-throughput

0.489

High

137223

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.489

High

137249

KT222
Keratin-like protein KRT222

1

1

High-throughput

0.489

High

137268

CML1
Chemerin-like receptor 1

1

3

High-throughput

0.489

High

137171

KPCG
Protein kinase C gamma type

1

0

High-throughput

0.486

High

137155

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

1

High-throughput

0.481

High

137174

ENOG
Gamma-enolase

1

1

High-throughput

0.481

High

137164

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

137172

LCK
Tyrosine-protein kinase Lck

1

1

High-throughput

0.479

High

137177

TPR
Nucleoprotein TPR

1

1

High-throughput

0.479

High

137194

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

137205

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.479

High

137226

CUL3
Cullin-3

1

1

High-throughput

0.479

High

48307

A0AVN2
BRCA1-associated RING domain protein 1

1

1

High-throughput

0.470

High

137222

TADBP
TAR DNA-binding protein 43

1

2

High-throughput

0.470

High

137255

DAAF4
Dynein axonemal assembly factor 4

1

0

High-throughput

0.460

High

137258

CBP
CREB-binding protein

1

0

Small-scale

0.460

High

137147

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

137156

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

137206

SC61B
Protein transport protein Sec61 subunit beta

1

0

Small-scale

0.458

High

137207

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

137217

K1C17
Keratin, type I cytoskeletal 17

1

0

High-throughput

0.458

High

137228

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.458

High

137233

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

137241

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

137274

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.458

High

137276

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

137282

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

137285

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

3368

A0A0S2Z4Q4
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.457

High

137181

FPR1
fMet-Leu-Phe receptor

1

3

High-throughput

0.445

High

137202

CXCR3
C-X-C chemokine receptor type 3

1

2

High-throughput

0.445

High

137256

LPAR1
Lysophosphatidic acid receptor 1

1

1

High-throughput

0.445

High

137221

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.438

High

137149

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.426

High

137151

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.426

High

137176

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.426

High

137239

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.426

High

3433

A0A0S2Z528
Proline-serine-threonine phosphatase interacting protein 1 isoform 3

1

1

High-throughput

0.417

High

137195

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

1

High-throughput

0.407

High

137231

CD226
CD226 antigen

1

2

High-throughput

0.407

High

137290

CAH14
Carbonic anhydrase 14

3

0

High-throughput

0.347

High

137269

KXDL1
KxDL motif-containing protein 1

2

0

High-throughput

0.335

High

137234

EDRF1
Erythroid differentiation-related factor 1

2

0

High-throughput

0.330

High

137182

EPHA1
Ephrin type-A receptor 1

2

0

High-throughput

0.328

High

137251

PNKD
Probable thioesterase PNKD

2

0

High-throughput

0.318

High

137167

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

2

0

High-throughput

0.316

High

137203

CRBB1
Beta-crystallin B1

2

0

High-throughput

0.316

High

137253

CA216
UPF0500 protein C1orf216

2

0

High-throughput

0.316

High

137270

KIFC3
Kinesin-like protein KIFC3

2

0

High-throughput

0.316

High

137185

TNR5
Tumor necrosis factor receptor superfamily member 5

2

0

High-throughput

0.313

High

137298

NPTN
Neuroplastin

2

0

High-throughput

0.313

High

137289

HECD1
E3 ubiquitin-protein ligase HECTD1

2

0

High-throughput

0.305

High

137235

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

0

High-throughput

0.299

High

137252

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.299

High

137260

SACA9
Sperm acrosome-associated protein 9

1

0

High-throughput

0.299

High

137204

SOX10
Transcription factor SOX-10

1

0

High-throughput

0.282

High

137243

ADCK1
AarF domain-containing protein kinase 1

1

0

High-throughput

0.282

High

137288

TBX21
T-box transcription factor TBX21

1

0

High-throughput

0.282

High

137152

ZN609
Zinc finger protein 609

1

0

High-throughput

0.279

Low

137188

ERP29
Endoplasmic reticulum resident protein 29

1

0

High-throughput

0.279

Low

137189

CD70
CD70 antigen

1

0

High-throughput

0.279

Low

137215

CBX1
Chromobox protein homolog 1

1

0

High-throughput

0.279

Low

137219

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.279

Low

137224

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

137225

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.279

Low

137271

SEM4C
Semaphorin-4C

1

0

High-throughput

0.279

Low

137272

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

137273

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

137281

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.279

Low

137287

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

137297

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

47284

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

137163

WFS1
Wolframin

1

0

High-throughput

0.268

Low

137245

Q86WV8
TSC complex subunit 1

1

0

High-throughput

0.268

Low

137154

STX7
Syntaxin-7

1

0

High-throughput

0.249

Low

137170

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

137178

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

137186

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

137191

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

137257

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

137283

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.249

Low

835

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

137159

XYLK
Glycosaminoglycan xylosylkinase

1

0

High-throughput

0.232

Low

137173

ACM4
Muscarinic acetylcholine receptor M4

1

0

High-throughput

0.232

Low

137190

CD68
Macrosialin

1

0

High-throughput

0.232

Low

137232

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low

137246

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

0

High-throughput

0.232

Low

137277

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.232

Low

137278

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.232

Low

137294

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025