Protein: RBM22
Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16)

Gene: RBM22
Organism: Homo sapiens
Interactions: 175
UniProt ID: Q9NW64

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1451085

PPIE
Peptidyl-prolyl cis-trans isomerase E

4

5

High-throughput

0.895

High

1286225

RALYL
RNA-binding Raly-like protein

3

20

High-throughput

0.861

High

471934

RU2B
U2 small nuclear ribonucleoprotein B''

2

20

High-throughput

0.811

High

1090307

ELAV2
ELAV-like protein 2

2

18

High-throughput

0.811

High

478227

SNRPA
U1 small nuclear ribonucleoprotein A

2

20

High-throughput

0.793

High

1111314

SNW1
SNW domain-containing protein 1

2

7

High-throughput

0.793

High

1127193

RBM39
RNA-binding protein 39

2

18

High-throughput

0.789

High

485745

RU2A
U2 small nuclear ribonucleoprotein A'

2

7

High-throughput

0.776

High

974062

RUXF
Small nuclear ribonucleoprotein F

4

12

High-throughput

0.697

High

256695

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

13

High-throughput

0.691

High

286090

SF3B1
Splicing factor 3B subunit 1

1

4

High-throughput

0.691

High

462676

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

19

High-throughput

0.691

High

685751

U2AF2
Splicing factor U2AF 65 kDa subunit

1

20

High-throughput

0.691

High

775336

FUS
RNA-binding protein FUS

1

19

High-throughput

0.691

High

1016644

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.691

High

1051524

SRS11
Serine/arginine-rich splicing factor 11

1

5

High-throughput

0.691

High

1099572

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.691

High

1101058

G3BP1
Ras GTPase-activating protein-binding protein 1

1

14

High-throughput

0.691

High

1109226

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

15

High-throughput

0.691

High

1148658

SF3A2
Splicing factor 3A subunit 2

1

8

High-throughput

0.691

High

1160106

SRSF7
Serine/arginine-rich splicing factor 7

1

19

High-throughput

0.691

High

1160320

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

14

High-throughput

0.691

High

1413393

RBM42
RNA-binding protein 42

1

16

High-throughput

0.691

High

1450687

DJC17
DnaJ homolog subfamily C member 17

1

4

High-throughput

0.691

High

1451089

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

1

High-throughput

0.691

High

1198537

CEP55
Centrosomal protein of 55 kDa

4

0

High-throughput

0.670

High

1322360

ZN444
Zinc finger protein 444

3

2

High-throughput

0.667

High

1346952

SNIP1
Smad nuclear-interacting protein 1

4

0

High-throughput

0.664

High

351361

SYF2
Pre-mRNA-splicing factor SYF2

3

1

High-throughput

0.662

High

973830

RUXE
Small nuclear ribonucleoprotein E

3

3

High-throughput

0.662

High

1451090

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

4

0

High-throughput

0.661

High

211436

RFOX2
RNA binding protein fox-1 homolog 2

1

17

High-throughput

0.656

High

1416133

RBM4
RNA-binding protein 4

1

19

High-throughput

0.656

High

1410078

USB1
U6 snRNA phosphodiesterase 1

3

0

High-throughput

0.638

High

1432367

PININ
Pinin

2

1

High-throughput

0.628

High

1451084

PRP19
Pre-mRNA-processing factor 19

2

7

High-throughput

0.628

High

1372100

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.621

High

1451086

YBOX2
Y-box-binding protein 2

1

11

High-throughput

0.621

High

134885

SAP18
Histone deacetylase complex subunit SAP18

1

3

High-throughput

0.618

High

485456

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

17

High-throughput

0.618

High

986764

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

6

High-throughput

0.618

High

1404451

CDC5L
Cell division cycle 5-like protein

1

7

High-throughput

0.618

High

1451080

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.618

High

298100

SPF27
Pre-mRNA-splicing factor SPF27

2

2

High-throughput

0.614

High

1114441

CUL3
Cullin-3

2

20

High-throughput

0.611

High

1387594

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

2

5

High-throughput

0.611

High

1449317

HOME3
Homer protein homolog 3

2

2

High-throughput

0.606

High

569276

YJU2B
Probable splicing factor YJU2B

2

3

High-throughput

0.601

High

1013975

TXN4A
Thioredoxin-like protein 4A

1

0

High-throughput

0.589

High

913815

ZN131
Zinc finger protein 131

1

0

High-throughput

0.586

High

961112

MGN
Protein mago nashi homolog

1

0

High-throughput

0.586

High

243102

PRKN
E3 ubiquitin-protein ligase parkin

2

13

High-throughput

0.584

High

373293

MYC
Myc proto-oncogene protein

2

11

High-throughput

0.584

High

1241815

PRP8
Pre-mRNA-processing-splicing factor 8

2

7

High-throughput

0.584

High

1451075

SPN90
NCK-interacting protein with SH3 domain

2

0

High-throughput

0.580

High

1209721

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.575

High

397060

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

281433

GGYF1
GRB10-interacting GYF protein 1

2

1

High-throughput

0.553

High

1063650

GOGA2
Golgin subfamily A member 2

2

6

High-throughput

0.553

High

938139

ANM2
Protein arginine N-methyltransferase 2

1

6

High-throughput

0.541

High

212824

ZN264
Zinc finger protein 264

1

1

High-throughput

0.536

High

335921

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

1

High-throughput

0.536

High

480322

RU1C
U1 small nuclear ribonucleoprotein C

1

3

High-throughput

0.536

High

542249

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

574490

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

7

High-throughput

0.536

High

807598

IF4A3
Eukaryotic initiation factor 4A-III

1

20

High-throughput

0.536

High

848185

MAGA1
Melanoma-associated antigen 1

1

5

High-throughput

0.536

High

1065464

SSRP1
FACT complex subunit SSRP1

1

5

High-throughput

0.536

High

1118173

DX39B
Spliceosome RNA helicase DDX39B

1

17

High-throughput

0.536

High

1128690

ZN460
Zinc finger protein 460

1

1

High-throughput

0.536

High

1138689

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

8

High-throughput

0.536

High

1149204

SF3A1
Splicing factor 3A subunit 1

1

8

High-throughput

0.536

High

1387279

HDA11
Histone deacetylase 11

1

6

High-throughput

0.536

High

1451070

ARGL1
Arginine and glutamate-rich protein 1

1

1

High-throughput

0.536

High

1451077

FOXJ2
Forkhead box protein J2

1

1

High-throughput

0.536

High

1451083

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

2

High-throughput

0.536

High

887265

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.527

High

1309676

ARHGJ
Rho guanine nucleotide exchange factor 19

2

7

High-throughput

0.521

High

1448059

ARHG4
Rho guanine nucleotide exchange factor 4

2

3

High-throughput

0.521

High

1036694

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

0

High-throughput

0.513

High

1356575

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.513

High

245163

AQR
RNA helicase aquarius

1

9

High-throughput

0.508

High

1414346

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

5

High-throughput

0.508

High

186067

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

8

High-throughput

0.501

High

1390979

THOC1
THO complex subunit 1

1

0

High-throughput

0.493

High

1369538

KIFA3
Kinesin-associated protein 3

1

4

High-throughput

0.489

High

223371

PRC1
Protein regulator of cytokinesis 1

1

8

High-throughput

0.481

High

286502

WBP4
WW domain-binding protein 4

1

8

High-throughput

0.481

High

321678

PRP6
Pre-mRNA-processing factor 6

1

14

High-throughput

0.481

High

336788

BAG4
BAG family molecular chaperone regulator 4

1

3

High-throughput

0.481

High

475024

VIME
Vimentin

1

2

High-throughput

0.481

High

765933

BMI1
Polycomb complex protein BMI-1

1

14

High-throughput

0.481

High

1103408

CTBP1
C-terminal-binding protein 1

1

4

High-throughput

0.481

High

1137678

EXOS7
Exosome complex component RRP42

1

3

High-throughput

0.481

High

1280756

YTHD3
YTH domain-containing family protein 3

1

11

High-throughput

0.481

High

1350467

BICD2
Protein bicaudal D homolog 2

1

5

High-throughput

0.481

High

1384039

EXOS8
Exosome complex component RRP43

1

3

High-throughput

0.481

High

1387409

ESS2
Splicing factor ESS-2 homolog

1

1

High-throughput

0.481

High

1397925

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

1

High-throughput

0.481

High

1418741

YTHD1
YTH domain-containing family protein 1

1

11

High-throughput

0.481

High

1448108

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.481

High

1451078

TFP11
Tuftelin-interacting protein 11

1

4

High-throughput

0.481

High

1451079

NXF1
Nuclear RNA export factor 1

1

2

High-throughput

0.481

High

404929

PRIO
Major prion protein

1

0

Small-scale

0.480

High

227686

SPOP
Speckle-type POZ protein

1

4

High-throughput

0.479

High

294414

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.479

High

316068

RECQ4
ATP-dependent DNA helicase Q4

1

13

High-throughput

0.479

High

346411

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

386290

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.479

High

404474

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

406714

MYCN
N-myc proto-oncogene protein

1

11

High-throughput

0.479

High

414720

P53
Cellular tumor antigen p53

1

4

High-throughput

0.479

High

589847

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

607157

CEBPB
CCAAT/enhancer-binding protein beta

1

9

High-throughput

0.479

High

696666

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

714460

PML
Protein PML

1

13

High-throughput

0.479

High

769333

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

854943

RECQ1
ATP-dependent DNA helicase Q1

1

10

High-throughput

0.479

High

879527

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

905196

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.479

High

942920

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

10

High-throughput

0.479

High

971172

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

974206

RUXG
Small nuclear ribonucleoprotein G

1

17

High-throughput

0.479

High

980429

H4
Histone H4

1

3

High-throughput

0.479

High

1048111

TLE3
Transducin-like enhancer protein 3

1

3

High-throughput

0.479

High

1107268

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1115459

CUL4B
Cullin-4B

1

20

High-throughput

0.479

High

1137546

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1140933

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

1255790

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.479

High

1290766

ZCH18
Zinc finger CCCH domain-containing protein 18

1

7

High-throughput

0.479

High

1314444

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.479

High

1339731

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1364278

TOPB1
DNA topoisomerase 2-binding protein 1

1

6

High-throughput

0.479

High

1367407

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1385641

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

1402323

RANB9
Ran-binding protein 9

1

4

High-throughput

0.479

High

1406784

BARD1
BRCA1-associated RING domain protein 1

1

4

High-throughput

0.479

High

1434043

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.479

High

1447335

ANLN
Anillin

1

4

High-throughput

0.479

High

1448774

RNC
Ribonuclease 3

1

5

High-throughput

0.479

High

1451071

AATF
Protein AATF

1

1

High-throughput

0.479

High

1451072

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1451073

WWOX
WW domain-containing oxidoreductase

1

4

High-throughput

0.479

High

1451074

ITSN2
Intersectin-2

1

2

High-throughput

0.479

High

1451076

CWC15
Spliceosome-associated protein CWC15 homolog

1

1

High-throughput

0.479

High

1451087

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

8

High-throughput

0.479

High

1451088

LC7L2
Putative RNA-binding protein Luc7-like 2

1

6

High-throughput

0.479

High

257276

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.460

High

1335190

NOA1
Nitric oxide-associated protein 1

1

0

High-throughput

0.460

High

1451081

HOOK1
Protein Hook homolog 1

1

0

High-throughput

0.460

High

446062

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

1326555

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.458

High

1339202

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

106733

APRIO
Alternative prion protein

1

2

Small-scale

0.457

High

64408

A6H8W8
Intersectin 2

1

2

High-throughput

0.445

High

71620

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

17

High-throughput

0.445

High

430426

JUN
Transcription factor Jun

1

8

High-throughput

0.445

High

1119330

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.445

High

1198672

NCBP3
Nuclear cap-binding protein subunit 3

1

3

High-throughput

0.445

High

1203271

ODFP2
Outer dense fiber protein 2

1

3

High-throughput

0.445

High

1451082

DDX41
Probable ATP-dependent RNA helicase DDX41

1

10

High-throughput

0.445

High

1146189

K1H1
Keratin, type I cuticular Ha1

1

1

High-throughput

0.439

High

1288051

PRP39
Pre-mRNA-processing factor 39

1

13

High-throughput

0.439

High

1406748

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

0

High-throughput

0.426

High

1445845

S40A1
Ferroportin

1

0

High-throughput

0.426

High

618428

TSN8
Tetraspanin-8

1

3

High-throughput

0.407

High

1433214

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

20

High-throughput

0.407

High

1256745

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.328

High

1383604

K1143
Uncharacterized protein KIAA1143

2

0

High-throughput

0.328

High

70507

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

377119

GLHA
Glycoprotein hormones alpha chain

1

0

High-throughput

0.279

Low

591383

CD44
CD44 antigen

1

0

High-throughput

0.279

Low

1437612

AGRL3
Adhesion G protein-coupled receptor L3

1

0

High-throughput

0.249

Low

1449622

CBLN4
Cerebellin-4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025