Protein: KCNJ8
ATP-sensitive inward rectifier potassium channel 8 (Inward rectifier K(+) channel Kir6.1) (Potassium channel, inwardly rectifying subfamily J member 8) (uKATP-1)

Gene: KCNJ8
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q15842

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0001774 - microglial cell activation
GO:0001822 - kidney development
GO:0002027 - regulation of heart rate
GO:0002250 - adaptive immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

705956

CD1B
T-cell surface glycoprotein CD1b

3

4

High-throughput

0.667

High

380429

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

3

2

High-throughput

0.656

High

1154812

MCLN3
Mucolipin-3

3

0

High-throughput

0.638

High

1154820

P2RX4
P2X purinoceptor 4

3

0

High-throughput

0.638

High

586181

CD1E
T-cell surface glycoprotein CD1e, membrane-associated

2

3

High-throughput

0.628

High

749776

CADH5
Cadherin-5

2

2

High-throughput

0.628

High

1154821

GPR21
Probable G-protein coupled receptor 21

2

3

High-throughput

0.628

High

1129206

KCJ11
ATP-sensitive inward rectifier potassium channel 11

1

15

Small-scale

0.618

High

139217

UPK2
Uroplakin-2

2

0

High-throughput

0.576

High

1154817

TECT2
Tectonic-2

2

1

High-throughput

0.574

High

894770

EMD
Emerin

2

2

High-throughput

0.553

High

438886

CD1A
T-cell surface glycoprotein CD1a

1

4

High-throughput

0.536

High

1154799

HFE
Hereditary hemochromatosis protein

1

1

High-throughput

0.536

High

1154803

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.536

High

1154804

TECT3
Tectonic-3

1

1

High-throughput

0.536

High

1154825

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

1154827

KCMB3
Calcium-activated potassium channel subunit beta-3

1

1

High-throughput

0.536

High

183932

S22A2
Solute carrier family 22 member 2

1

0

High-throughput

0.513

High

407175

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.513

High

688666

NKG2C
NKG2-C type II integral membrane protein

1

0

High-throughput

0.513

High

1154800

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.513

High

1154806

LRC55
Leucine-rich repeat-containing protein 55

1

0

High-throughput

0.513

High

1154811

TM130
Transmembrane protein 130

1

0

High-throughput

0.513

High

1154826

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.513

High

1154829

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.513

High

380631

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

2

High-throughput

0.479

High

1154816

TSN17
Tetraspanin-17

1

1

High-throughput

0.479

High

568062

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

0

High-throughput

0.458

High

1042745

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

0

High-throughput

0.458

High

1154809

TEFF1
Tomoregulin-1

1

0

High-throughput

0.458

High

1154831

AT1B4
Protein ATP1B4

1

0

High-throughput

0.458

High

97106

E9PMV2
Major histocompatibility complex, class II, DQ alpha 1

1

3

High-throughput

0.445

High

379799

IGHD
Immunoglobulin heavy constant delta

1

1

High-throughput

0.445

High

877670

SL9A3
Sodium/hydrogen exchanger 3

1

1

High-throughput

0.445

High

1154801

CTL4
Choline transporter-like protein 4

1

2

High-throughput

0.445

High

1154808

CTL2
Choline transporter-like protein 2

1

2

High-throughput

0.445

High

1154810

AGRG5
Adhesion G-protein coupled receptor G5

1

1

High-throughput

0.445

High

1154814

CTL1
Choline transporter-like protein 1

1

2

High-throughput

0.445

High

1154819

SL9A7
Sodium/hydrogen exchanger 7

1

1

High-throughput

0.445

High

1154807

S13A5
Na(+)/citrate cotransporter

1

0

High-throughput

0.426

High

1154818

B3A4
Anion exchange protein 4

1

0

High-throughput

0.426

High

1154822

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

0

High-throughput

0.426

High

1154830

SO3A1
Solute carrier organic anion transporter family member 3A1

1

0

High-throughput

0.426

High

1154802

NADL2
Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2

3

0

High-throughput

0.347

High

1154813

TMED6
Transmembrane emp24 domain-containing protein 6

2

0

High-throughput

0.328

High

1154823

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

0

High-throughput

0.328

High

1154815

TMM54
Transmembrane protein 54

2

0

High-throughput

0.316

High

1154828

TM140
Transmembrane protein 140

2

0

High-throughput

0.316

High

1154805

PXDC2
Plexin domain-containing protein 2

1

0

High-throughput

0.279

Low

1154824

WNT8A
Protein Wnt-8a

1

0

High-throughput

0.279

Low

1005540

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025