Protein: B3A4
Anion exchange protein 4 (AE 4) (Anion exchanger 4) (Sodium bicarbonate cotransporter 5) (Solute carrier family 4 member 9)

Gene: B3A4, SLC4A9
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q96Q91

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0008510 - sodium:bicarbonate symporter activity
GO:0015701 - bicarbonate transport
GO:0016323 - basolateral plasma membrane
GO:0035725 - sodium ion transmembrane transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1047707

NOTC2
Neurogenic locus notch homolog protein 2

1

3

High-throughput

0.575

High

243823

ADCY3
Adenylate cyclase type 3

1

3

High-throughput

0.445

High

321337

ERLN2
Erlin-2

1

10

High-throughput

0.445

High

541645

FGFR1
Fibroblast growth factor receptor 1

1

12

High-throughput

0.445

High

600904

HSP76
Heat shock 70 kDa protein 6

1

1

High-throughput

0.445

High

761490

HS71L
Heat shock 70 kDa protein 1-like

1

1

High-throughput

0.445

High

787335

ACV1B
Activin receptor type-1B

1

7

High-throughput

0.445

High

870451

SC6A9
Sodium- and chloride-dependent glycine transporter 1

1

1

High-throughput

0.445

High

1386179

ASTRA
Protein Aster-A

1

2

High-throughput

0.445

High

1400629

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.445

High

1400632

AT131
Endoplasmic reticulum transmembrane helix translocase

1

6

High-throughput

0.445

High

1400633

WDR6
tRNA

1

6

High-throughput

0.445

High

1400644

LRP12
Low-density lipoprotein receptor-related protein 12

1

3

High-throughput

0.445

High

888965

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.426

High

1154818

KCNJ8
ATP-sensitive inward rectifier potassium channel 8

1

0

High-throughput

0.426

High

1326215

PNKD
Probable thioesterase PNKD

1

0

High-throughput

0.426

High

1356275

ABHD3
Phospholipase ABHD3

1

0

High-throughput

0.426

High

72675

UPK3L
Uroplakin-3b-like protein 1

1

1

High-throughput

0.407

High

170927

CLGN
Calmegin

1

6

High-throughput

0.407

High

175477

AREL1
Apoptosis-resistant E3 ubiquitin protein ligase 1

1

4

High-throughput

0.407

High

283339

ERLN1
Erlin-1

1

8

High-throughput

0.407

High

322985

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

1

High-throughput

0.407

High

344003

HS74L
Heat shock 70 kDa protein 4L

1

4

High-throughput

0.407

High

347878

BAG3
BAG family molecular chaperone regulator 3

1

3

High-throughput

0.407

High

399729

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

1

High-throughput

0.407

High

643996

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.407

High

761830

HSP74
Heat shock 70 kDa protein 4

1

4

High-throughput

0.407

High

944307

TMM33
Transmembrane protein 33

1

4

High-throughput

0.407

High

1010518

EREP3
Protein ENTREP3

1

1

High-throughput

0.407

High

1097870

STX5
Syntaxin-5

1

5

High-throughput

0.407

High

1105545

OS9
Protein OS-9

1

3

High-throughput

0.407

High

1147826

DHC24
Delta(24)-sterol reductase

1

1

High-throughput

0.407

High

1162330

CEGT
Ceramide glucosyltransferase

1

1

High-throughput

0.407

High

1277279

S46A3
Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3

1

1

High-throughput

0.407

High

1278666

CF120
UPF0669 protein C6orf120

1

1

High-throughput

0.407

High

1287416

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

6

High-throughput

0.407

High

1357312

THEM6
Protein THEM6

1

2

High-throughput

0.407

High

1358340

SCFD1
Sec1 family domain-containing protein 1

1

1

High-throughput

0.407

High

1365213

HS105
Heat shock protein 105 kDa

1

4

High-throughput

0.407

High

1372373

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

4

High-throughput

0.407

High

1388082

ERLEC
Endoplasmic reticulum lectin 1

1

3

High-throughput

0.407

High

1400630

NFIP1
NEDD4 family-interacting protein 1

1

2

High-throughput

0.407

High

1400634

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

1

High-throughput

0.407

High

1400636

FA8A1
Protein FAM8A1

1

1

High-throughput

0.407

High

1400637

SE1L1
Protein sel-1 homolog 1

1

1

High-throughput

0.407

High

1400638

AMFR
E3 ubiquitin-protein ligase AMFR

1

4

High-throughput

0.407

High

1400639

BAG5
BAG family molecular chaperone regulator 5

1

3

High-throughput

0.407

High

1400640

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

High-throughput

0.407

High

1400641

DJC16
DnaJ homolog subfamily C member 16

1

2

High-throughput

0.407

High

1400642

SGT1
Protein SGT1 homolog

1

2

High-throughput

0.407

High

50670

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

60397

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.232

Low

291497

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.232

Low

322452

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.232

Low

469179

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.232

Low

549219

CDK4
Cyclin-dependent kinase 4

1

0

High-throughput

0.232

Low

856875

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.232

Low

921995

COPA
Coatomer subunit alpha

1

0

High-throughput

0.232

Low

1103573

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

0

High-throughput

0.232

Low

1197267

MBRL
Membralin

1

0

High-throughput

0.232

Low

1218458

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

0

High-throughput

0.232

Low

1313221

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

0

High-throughput

0.232

Low

1315475

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.232

Low

1335154

LEMD2
LEM domain-containing protein 2

1

0

High-throughput

0.232

Low

1337637

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.232

Low

1347637

NPL4
Nuclear protein localization protein 4 homolog

1

0

High-throughput

0.232

Low

1351448

BRX1
Ribosome biogenesis protein BRX1 homolog

1

0

High-throughput

0.232

Low

1393609

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.232

Low

1395618

RN170
E3 ubiquitin-protein ligase RNF170

1

0

High-throughput

0.232

Low

1400631

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

0

High-throughput

0.232

Low

1400635

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.232

Low

1400643

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025