Protein: CSTF1
Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50)

Gene: CSTF1
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q05048

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005848 - mRNA cleavage stimulating factor complex
GO:0031124 - mRNA 3'-end processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1050303

BARD1
BRCA1-associated RING domain protein 1

7

8

Small-scale

0.748

High

1050281

CSTF3
Cleavage stimulation factor subunit 3

2

20

Small-scale

0.737

High

1050316

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

10

High-throughput

0.691

High

1050291

A16L1
Autophagy-related protein 16-1

2

17

High-throughput

0.659

High

667278

RPB1
DNA-directed RNA polymerase II subunit RPB1

3

5

Small-scale

0.651

High

799022

BRCA1
Breast cancer type 1 susceptibility protein

3

11

Small-scale

0.646

High

991169

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

10

High-throughput

0.628

High

1050308

CSTFT
Cleavage stimulation factor subunit 2 tau variant

2

7

High-throughput

0.628

High

1050306

TOLIP
Toll-interacting protein

3

1

High-throughput

0.619

High

1006985

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.618

High

854831

RECQ1
ATP-dependent DNA helicase Q1

1

20

High-throughput

0.618

High

1042850

ERCC6
DNA excision repair protein ERCC-6

1

20

Small-scale

0.618

High

1050305

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

8

High-throughput

0.618

High

354220

ZBED1
E3 SUMO-protein ligase ZBED1

2

0

High-throughput

0.602

High

1050288

H2A2C
Histone H2A type 2-C

1

8

Small-scale

0.579

High

395966

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

934505

TERA
Transitional endoplasmic reticulum ATPase

1

6

Small-scale

0.561

High

995550

ACTC
Actin, alpha cardiac muscle 1

1

7

High-throughput

0.553

High

1050293

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.553

High

1050309

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.553

High

478005

SNRPA
U1 small nuclear ribonucleoprotein A

1

12

High-throughput

0.536

High

541963

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.536

High

574227

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

8

High-throughput

0.536

High

681795

RBTN2
Rhombotin-2

1

3

High-throughput

0.536

High

708952

T2EB
Transcription initiation factor IIE subunit beta

1

1

High-throughput

0.536

High

775026

FUS
RNA-binding protein FUS

1

19

High-throughput

0.536

High

1050287

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

15

High-throughput

0.536

High

1050292

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

1

High-throughput

0.536

High

1050301

RBM14
RNA-binding protein 14

1

11

High-throughput

0.536

High

1050307

RGAP1
Rac GTPase-activating protein 1

1

3

High-throughput

0.536

High

1050314

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

1

5

High-throughput

0.536

High

241466

PRKN
E3 ubiquitin-protein ligase parkin

2

13

High-throughput

0.533

High

935719

MFAP4
Microfibril-associated glycoprotein 4

1

1

High-throughput

0.489

High

939894

DLX6
Homeobox protein DLX-6

1

8

High-throughput

0.489

High

1050304

FEM1A
Protein fem-1 homolog A

1

4

High-throughput

0.489

High

128999

MEN1
Menin

1

6

High-throughput

0.479

High

247844

NUPR1
Nuclear protein 1

1

5

High-throughput

0.479

High

259837

BRD4
Bromodomain-containing protein 4

1

19

High-throughput

0.479

High

320664

UBXN7
UBX domain-containing protein 7

1

3

High-throughput

0.479

High

337339

PARN
Poly(A)-specific ribonuclease PARN

1

2

Small-scale

0.479

High

339971

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

5

Small-scale

0.479

High

371828

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

472668

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

13

High-throughput

0.479

High

485087

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

Small-scale

0.479

High

550999

PCNA
Proliferating cell nuclear antigen

1

1

Small-scale

0.479

High

590409

GATA1
Erythroid transcription factor

1

13

High-throughput

0.479

High

750407

CSTF2
Cleavage stimulation factor subunit 2

1

7

Small-scale

0.479

High

765428

BMI1
Polycomb complex protein BMI-1

1

17

High-throughput

0.479

High

862061

YAP1
Transcriptional coactivator YAP1

1

10

High-throughput

0.479

High

904629

MECP2
Methyl-CpG-binding protein 2

1

12

High-throughput

0.479

High

1050282

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

High-throughput

0.479

High

1050283

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

5

High-throughput

0.479

High

1050284

BIRC3
Baculoviral IAP repeat-containing protein 3

1

7

High-throughput

0.479

High

1050294

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1050296

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1050297

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

1050298

OPTN
Optineurin

1

20

High-throughput

0.479

High

1050299

ZBT10
Zinc finger and BTB domain-containing protein 10

1

4

Small-scale

0.479

High

1050302

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1050312

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1050315

FAF1
FAS-associated factor 1

1

3

High-throughput

0.479

High

288297

GCM2
Chorion-specific transcription factor GCMb

1

1

High-throughput

0.470

High

711629

3MG
DNA-3-methyladenine glycosylase

1

0

Small-scale

0.458

High

1050289

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.445

High

105796

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

416012

CP1A1
Cytochrome P450 1A1

1

2

High-throughput

0.437

High

880091

AL9A1
4-trimethylaminobutyraldehyde dehydrogenase

1

3

High-throughput

0.437

High

1050285

NFIX
Nuclear factor 1 X-type

1

17

High-throughput

0.437

High

1050286

KIF14
Kinesin-like protein KIF14

1

12

High-throughput

0.437

High

1050290

TENS2
Tensin-2

1

6

High-throughput

0.437

High

1050295

TIP
T-cell immunomodulatory protein

1

1

High-throughput

0.437

High

1050300

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.437

High

1050311

PLK2
Serine/threonine-protein kinase PLK2

1

5

High-throughput

0.437

High

1050313

UBQL2
Ubiquilin-2

1

3

High-throughput

0.437

High

563663

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.407

High

1050310

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.407

High

562716

BMP1
Bone morphogenetic protein 1

2

0

High-throughput

0.328

High


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Last updated: 11Aug2025